Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Drug Eruptions D003875 30 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Alopecia Areata D000506 6 associated lipids
Acne Keloid D000153 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Parodi A et al. Treatment of rosacea. 2011 Ann Dermatol Venereol pmid:22183101
Kircik LH Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study. 2011 J Drugs Dermatol pmid:21637899
Wheeland RG and Dhawan S Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. 2011 J Drugs Dermatol pmid:21637900
van Zuuren EJ et al. Interventions for rosacea. 2011 Cochrane Database Syst Rev pmid:21412882
Sato C et al. Cellulase applied to the leaves of sweet pepper (Capsicum annuum L. var. grossum) upregulates the production of salicylic and azelaic acids. 2011 Biosci. Biotechnol. Biochem. pmid:21512237
Castellucci N et al. Formation of gels in the presence of metal ions. 2011 Amino Acids pmid:21487726
McFalda WL and Roebuck HL Rational management of papulopustular rosacea with concomitant facial seborrheic dermatitis: a case report. 2011 J Clin Aesthet Dermatol pmid:21278898
Cuevas P et al. Long-term effectiveness of dobesilate in the treatment of papulopustular rosacea. 2011 BMJ Case Rep pmid:22675033
Fabbrocini G et al. Skin needling to enhance depigmenting serum penetration in the treatment of melasma. 2011 Plast Surg Int pmid:22567235
Schauber J [Antimicrobial peptides, Vitamin D₃ and more. How rosacea may develop]. 2011 Hautarzt pmid:22002717