Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Drug Eruptions D003875 30 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Alopecia Areata D000506 6 associated lipids
Acne Keloid D000153 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Khanna N and Rasool S Facial melanoses: Indian perspective. 2011 Sep-Oct Indian J Dermatol Venereol Leprol pmid:21860153
Rozema E et al. Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. 2012 Evid Based Complement Alternat Med pmid:22675394
Zhao H et al. Metabolomics-based study of clinical and animal plasma samples in coronary heart disease with blood stasis syndrome. 2012 Evid Based Complement Alternat Med pmid:22675387
Simonart T Newer approaches to the treatment of acne vulgaris. 2012 Am J Clin Dermatol pmid:22920095
Li N et al. Effect of ionization and vehicle on skin absorption and penetration of azelaic acid. 2012 Drug Dev Ind Pharm pmid:22111946
Zoeller M et al. Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid. 2012 Plant Physiol. pmid:22822212
Bhatia ND and Del Rosso JQ Optimal management of papulopustular rosacea: rationale for combination therapy. 2012 J Drugs Dermatol pmid:22777226
Hsieh PW et al. The co-drug of conjugated hydroquinone and azelaic acid to enhance topical skin targeting and decrease penetration through the skin. 2012 Eur J Pharm Biopharm pmid:22469554
Shalita AR et al. Inflammatory acne management with a novel prescription dietary supplement. 2012 J Drugs Dermatol pmid:23377512
Matsubara T et al. Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis. 2012 Cell Metab. pmid:23140643