Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Rhinophyma D012224 1 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Pituitary Apoplexy D010899 1 associated lipids
Acne Keloid D000153 1 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Melanosis D008548 4 associated lipids
Alopecia Areata D000506 6 associated lipids
Facial Dermatoses D005148 7 associated lipids
Keratosis D007642 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Karimi AA et al. Improvement of tissue survival of skin flaps by 5α-reductase inhibitors: possible involvement of nitric oxide and inducible nitric oxide synthase. 2015 Iran. Biomed. J. pmid:25864816
Ganzetti G et al. Rosacea: could topical azelaic acid and oral tetracyclines modify videocapillaroscopic pattern? 2014 Mar-Apr Skinmed pmid:24933858
Gołębiowski M et al. Antimicrobial activity of untypical lipid compounds in the cuticular and internal lipids of four fly species. 2014 J. Appl. Microbiol. pmid:24238211
Wang C et al. Free radicals mediate systemic acquired resistance. 2014 Cell Rep pmid:24726369
Shariff A et al. Acne vulgaris in the context of complex medical co-morbities: the management of severe acne vulgaris in a female with retinitis pigmentosa - utilizing pulse dye laser in conjunction with medical therapy. 2014 Dermatol. Online J. pmid:24656277
Del Rosso JQ and Kircik LH Update on the management of rosacea: a status report on the current role and new horizons with topical azelaic acid. 2014 J Drugs Dermatol pmid:25607798
Del Rosso JQ et al. Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 5: a guide on the management of rosacea. 2014 Cutis pmid:24738094
Han S et al. Identification of unknown impurity of azelaic acid in liposomal formulation assessed by HPLC-ELSD, GC-FID, and GC-MS. 2014 AAPS PharmSciTech pmid:24166667
Sieber MA and Hegel JK Azelaic acid: Properties and mode of action. 2014 Skin Pharmacol Physiol pmid:24280644
Vargas-Diez E et al. Azelaic acid in the treatment of acne in adult females: case reports. 2014 Skin Pharmacol Physiol pmid:24280645