Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Acne Keloid D000153 1 associated lipids
Rhinophyma D012224 1 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Pituitary Apoplexy D010899 1 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Melanosis D008548 4 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Alopecia Areata D000506 6 associated lipids
Facial Dermatoses D005148 7 associated lipids
Keratosis D007642 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Reis CP et al. Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. 2013 Microsc. Microanal. pmid:23673203
Briganti S et al. Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ. 2013 Exp. Dermatol. pmid:23278893
Pazoki-Toroudi H et al. Therapeutic effects of minoxidil high extra combination therapy in patients with androgenetic alopecia. 2012 Sep-Oct Skinmed pmid:23163069
Sarkar R et al. Newer and upcoming therapies for melasma. 2012 Jul-Aug Indian J Dermatol Venereol Leprol pmid:22772611
Simonart T Newer approaches to the treatment of acne vulgaris. 2012 Am J Clin Dermatol pmid:22920095
Li N et al. Effect of ionization and vehicle on skin absorption and penetration of azelaic acid. 2012 Drug Dev Ind Pharm pmid:22111946
Zoeller M et al. Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid. 2012 Plant Physiol. pmid:22822212
Bhatia ND and Del Rosso JQ Optimal management of papulopustular rosacea: rationale for combination therapy. 2012 J Drugs Dermatol pmid:22777226
Shalita AR et al. Inflammatory acne management with a novel prescription dietary supplement. 2012 J Drugs Dermatol pmid:23377512
Matsubara T et al. Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis. 2012 Cell Metab. pmid:23140643