Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Acne Keloid D000153 1 associated lipids
Alopecia Areata D000506 6 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Erythema D004890 22 associated lipids
Facial Dermatoses D005148 7 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Melnik BC and Schmitz G Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? 2013 Exp. Dermatol. pmid:23800068
Yu K et al. A feedback regulatory loop between G3P and lipid transfer proteins DIR1 and AZI1 mediates azelaic-acid-induced systemic immunity. 2013 Cell Rep pmid:23602565
Pazoki-Toroudi H et al. Therapeutic effects of minoxidil high extra combination therapy in patients with androgenetic alopecia. 2012 Sep-Oct Skinmed pmid:23163069
Sarkar R et al. Newer and upcoming therapies for melasma. 2012 Jul-Aug Indian J Dermatol Venereol Leprol pmid:22772611
Simonart T Newer approaches to the treatment of acne vulgaris. 2012 Am J Clin Dermatol pmid:22920095
Li N et al. Effect of ionization and vehicle on skin absorption and penetration of azelaic acid. 2012 Drug Dev Ind Pharm pmid:22111946
Bhatia ND and Del Rosso JQ Optimal management of papulopustular rosacea: rationale for combination therapy. 2012 J Drugs Dermatol pmid:22777226
Fallen RS and Gooderham M Rosacea: update on management and emerging therapies. 2012 Skin Therapy Lett. pmid:23223767
Shalita AR et al. Inflammatory acne management with a novel prescription dietary supplement. 2012 J Drugs Dermatol pmid:23377512
Matsubara T et al. Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis. 2012 Cell Metab. pmid:23140643