Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Disease Resistance D060467 12 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Hyperpigmentation D017495 11 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Rosacea D012393 13 associated lipids
Rhinophyma D012224 1 associated lipids
Psoriasis D011565 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
May D et al. Clinical inquiries. What is the most effective treatment for acne rosacea? 2011 J Fam Pract pmid:21301648
Pazoki-Toroudi H et al. Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne vulgaris. 2011 Cutan Ocul Toxicol pmid:21612319
Karavelidis V et al. Evaluating the effects of crystallinity in new biocompatible polyester nanocarriers on drug release behavior. 2011 Int J Nanomedicine pmid:22162659
Schnopp C and Mempel M Acne vulgaris in children and adolescents. 2011 Minerva Pediatr. pmid:21909065
Del Rosso JQ and Bhatia N Azelaic acid gel 15% in the management of papulopustular rosacea: a status report on available efficacy data and clinical application. 2011 Cutis pmid:21916272
Sheth VM and Pandya AG Melasma: a comprehensive update: part II. 2011 J. Am. Acad. Dermatol. pmid:21920242
Yu L et al. Metabolomic phenotype of gastric cancer and precancerous stages based on gas chromatography time-of-flight mass spectrometry. 2011 J. Gastroenterol. Hepatol. pmid:21443661
Wang H et al. [Chemical constituents of Halenia elliptica]. 2011 Zhongguo Zhong Yao Za Zhi pmid:22779176
Vinaixa M et al. Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. 2011 PLoS ONE pmid:22194988
Chudasama A et al. Investigation of microemulsion system for transdermal delivery of itraconazole. 2011 J Adv Pharm Technol Res pmid:22171289