Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Disease Resistance D060467 12 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Hyperpigmentation D017495 11 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Rosacea D012393 13 associated lipids
Rhinophyma D012224 1 associated lipids
Psoriasis D011565 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Nazzaro-Porro M Azelaic acid. 1987 J. Am. Acad. Dermatol. pmid:2963038
Piquero Martín J et al. [Double-blind clinical study of the treatment of melasma with azelaic acid versus hydroquinone]. 1988 Med Cutan Ibero Lat Am pmid:3073279
Mingrone G et al. Influence of sodium salts of saturated medium chain length (C6, C9, C10 and C12) dicarboxylic acids on the uterine horn of rat in vitro. 1988 Q J Exp Physiol pmid:3164112
Stamatiadis D et al. Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid. 1988 Br. J. Dermatol. pmid:3207614
Sowden J et al. Malignant melanoma arising in the scar of lupus vulgaris and response to treatment with topical azelaic acid. 1988 Clin. Exp. Dermatol. pmid:3256454
Azelaic acid in lentigo maligna. 1987 Br. J. Dermatol. pmid:3580294
Schallreuter KU and Wood JM Azelaic acid as a competitive inhibitor of thioredoxin reductase in human melanoma cells. 1987 Cancer Lett. pmid:3652030
Grosshans E and Chartier C [Therapeutic depigmentation agents]. 1987 Schweiz. Rundsch. Med. Prax. pmid:3671942
Geier G et al. [Effect of azelaic acid on the growth of melanoma cell cultures in comparison with fibroblast cultures]. 1986 Hautarzt pmid:3700102
McLean DI and Peter KK Apparent progression of lentigo maligna to invasive melanoma during treatment with topical azelaic acid. 1986 Br. J. Dermatol. pmid:3718862