Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Disease Resistance D060467 12 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Hyperpigmentation D017495 11 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Rosacea D012393 13 associated lipids
Rhinophyma D012224 1 associated lipids
Psoriasis D011565 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Robins EJ et al. Effectiveness of azelaic acid as a depigmenting and chemotherapeutic agent. 1986 J. Invest. Dermatol. pmid:3734479
Ward BJ et al. Effect of L-carnitine on cultured murine melanoma cells exposed to azelaic acid. 1986 J. Invest. Dermatol. pmid:3745962
Ortonne JP [Depigmenting chemical agents]. 1986 Ann Dermatol Venereol pmid:3800227
Hu F et al. Effects of dicarboxylic acids on normal and malignant melanocytes in culture. 1986 Br. J. Dermatol. pmid:3942687
Rocchiccioli F et al. Medium- and long-chain dicarboxylic aciduria in patients with Zellweger syndrome and neonatal adrenoleukodystrophy. 1986 Pediatr. Res. pmid:3945517
Picardo M et al. Activity of azelaic acid on cultures of lymphoma- and leukemia-derived cell lines, normal resting and stimulated lymphocytes and 3T3 fibroblasts. 1985 Biochem. Pharmacol. pmid:4004885
Robins EJ et al. Effect of dicarboxylic acids on Harding-Passey and Cloudman S91 melanoma cells in tissue culture. 1985 J. Invest. Dermatol. pmid:4031537
Pathak MA et al. An evaluation of the effectiveness of azelaic acid as a depigmenting and chemotherapeutic agent. 1985 J. Invest. Dermatol. pmid:4031538
Leibl H et al. Inhibition of DNA synthesis of melanoma cells by azelaic acid. 1985 J. Invest. Dermatol. pmid:4056455
Robins EJ et al. Ultrastructural observations on the effect of azelaic acid on normal human melanocytes and a human melanoma cell line in tissue culture. 1985 Br. J. Dermatol. pmid:4096883