Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
pmid:20017486
Sobottka A and Lehmann P [Rosacea 2009 : new advances in pathophysiology, clinical staging and therapeutic strategies]. 2009 Hautarzt pmid:19957073
Fujitani K et al. Preparation of polycarboxylic acids by oxidative cleavage with oxygen / Co-Mn-Br system. 2009 J Oleo Sci pmid:19915320
pmid:19907406
Wu YH et al. Effects of Chinese herbal medicine combined with He-Ne laser on lipoperoxide and superoxide dismutase in chloasma patients. 2009 J Tradit Chin Med pmid:19894376
Litvinov D et al. Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. 2010 Atherosclerosis pmid:19880116
Ebanks JP et al. Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration. 2009 Int J Mol Sci pmid:19865532
Elsaie ML and Choudhary S Updates on the pathophysiology and management of acne rosacea. 2009 Postgrad Med pmid:19820288
Jansen T et al. Steroid-induced periorificial dermatitis in children--clinical features and response to azelaic acid. 2010 Mar-Apr Pediatr Dermatol pmid:19804495
Panyosak A et al. Safety assessment of azelaic acid and its derivatives entrapped in nanovesicles. 2009 Hum Exp Toxicol pmid:19755450
Del Rosso JQ The use of moisturizers as an integral component of topical therapy for rosacea: clinical results based on the Assessment of Skin Characteristics Study. 2009 Cutis pmid:19746764
Que SK and Bergstrom KG Hyperpigmentation: old problem, new therapies. 2009 J Drugs Dermatol pmid:19746682
Goldgar C et al. Treatment options for acne rosacea. 2009 Am Fam Physician pmid:19725487
pmid:19643540
Lanz C et al. Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. 2009 Radiat. Res. pmid:19630524
Shah J Plants under attack: systemic signals in defence. 2009 Curr. Opin. Plant Biol. pmid:19608451
pmid:19608057
Thiboutot DM et al. A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. 2009 J Drugs Dermatol pmid:19588640
Culp B and Scheinfeld N Rosacea: a review. 2009 P T pmid:19562004
Korting HC and Schöllmann C Current topical and systemic approaches to treatment of rosacea. 2009 J Eur Acad Dermatol Venereol pmid:19508315
Bowler PJ Impact on facial rejuvenation with dermatological preparations. 2009 Clin Interv Aging pmid:19503770
pmid:19465852
Purdy S and Deberker D Acne vulgaris. 2008 BMJ Clin Evid pmid:19450306
Parker JE The quest for long-distance signals in plant systemic immunity. 2009 Sci Signal pmid:19436056
pmid:19433342
Del Rosso JQ et al. Impact of order of application of moisturizers on percutaneous absorption kinetics: evaluation of sequential application of moisturizer lotions and azelaic acid gel 15% using a human skin model. 2009 Cutis pmid:19363903
Jung HW et al. Priming in systemic plant immunity. 2009 Science pmid:19342588
Gooderham M Rosacea and its topical management. 2009 Skin Therapy Lett. pmid:19330270
Melnik BC et al. Anti-acne agents attenuate FGFR2 signal transduction in acne. 2009 J. Invest. Dermatol. pmid:19225542
pmid:19160531
pmid:19126734
Bertuzzi A et al. Pharmacokinetic analysis of azelaic acid disodium salt. A proposed substrate for total parenteral nutrition. 1991 Clin Pharmacokinet pmid:1908756
pmid:19055345
pmid:19022456
Lee GS Intravenous vitamin C in the treatment of post-laser hyperpigmentation for melasma: a short report. 2008 J Cosmet Laser Ther pmid:18830869
Gollnick H and Layton A Azelaic acid 15% gel in the treatment of rosacea. 2008 Expert Opin Pharmacother pmid:18803456
Rup S et al. The ultrasound-assisted oxidative scission of monoenic fatty acids by ruthenium tetroxide catalysis: influence of the mixture of solvents. 2009 Ultrason Sonochem pmid:18799341
pmid:18728922
Mostafa FF et al. Comparative study of some treatment modalities of rosacea. 2009 J Eur Acad Dermatol Venereol pmid:18705632
Akamatsu H et al. Inhibitory effect of azelaic acid on neutrophil functions: a possible cause for its efficacy in treating pathogenetically unrelated diseases. 1991 Arch. Dermatol. Res. pmid:1867478
pmid:18641447
Crea F et al. Sequestering ability of polycarboxylic ligands towards dioxouranium(VI). 2008 Talanta pmid:18585146
Thiboutot DM et al. Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. 2008 J Drugs Dermatol pmid:18561584
pmid:18535811
Piskin S and Uzunali E A review of the use of adapalene for the treatment of acne vulgaris. 2007 Ther Clin Risk Manag pmid:18472984
Stewart JJ Application of the PM6 method to modeling the solid state. 2008 J Mol Model pmid:18449579
De Filippis D et al. Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats. 2009 J. Cell. Mol. Med. pmid:18429935
pmid:18394082
Gollnick H [Azelaic acid for keratinization disorders?]. 1991 Med Monatsschr Pharm pmid:1838401
pmid:18377339