| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Iraji F et al. | Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial. | 2010 | J Drugs Dermatol | pmid:20684146 |
| Kircik LH | Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study. | 2011 | J Drugs Dermatol | pmid:21637899 |
| Wheeland RG and Dhawan S | Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. | 2011 | J Drugs Dermatol | pmid:21637900 |
| Que SK and Bergstrom KG | Hyperpigmentation: old problem, new therapies. | 2009 | J Drugs Dermatol | pmid:19746682 |
| Thiboutot DM et al. | A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. | 2009 | J Drugs Dermatol | pmid:19588640 |
| Del Rosso JQ et al. | Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea. | 2010 | J Drugs Dermatol | pmid:20645521 |
| Conde JF et al. | Managing rosacea: a review of the use of metronidazole alone and in combination with oral antibiotics. | 2007 | J Drugs Dermatol | pmid:17679183 |
| Thiboutot D | Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris. | 2008 | J Drugs Dermatol | pmid:18246693 |
| Ziel K et al. | Cumulative irritation potential of metronidazole gel compared to azelaic acid gel after repeated applications to healthy skin. | 2005 Nov-Dec | J Drugs Dermatol | pmid:16302558 |
| Nally JB and Berson DS | Topical therapies for rosacea. | 2006 | J Drugs Dermatol | pmid:16468288 |
| Fleischer A and Suephy C | The face and mind evaluation study: an examination of the efficacy of rosacea treatment using physician ratings and patients' self-reported quality of life. | 2005 Sep-Oct | J Drugs Dermatol | pmid:16167417 |
| Thiboutot DM et al. | Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. | 2008 | J Drugs Dermatol | pmid:18561584 |
| Bhatia ND and Del Rosso JQ | Optimal management of papulopustular rosacea: rationale for combination therapy. | 2012 | J Drugs Dermatol | pmid:22777226 |
| Del Rosso JQ and Kircik LH | Update on the management of rosacea: a status report on the current role and new horizons with topical azelaic acid. | 2014 | J Drugs Dermatol | pmid:25607798 |
| Woolery-Lloyd HC et al. | Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color. | 2013 | J Drugs Dermatol | pmid:23652891 |
| Jackson JM et al. | Efficacy of extended-release 45 mg oral minocycline and extended-release 45 mg oral minocycline plus 15% azelaic acid in the treatment of acne rosacea. | 2013 | J Drugs Dermatol | pmid:23545911 |
| Shalita AR et al. | Inflammatory acne management with a novel prescription dietary supplement. | 2012 | J Drugs Dermatol | pmid:23377512 |
| Fluhr JW and Degitz K | [Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy]. | 2010 | J Dtsch Dermatol Ges | pmid:20482689 |
| Gollnick HP et al. | [Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies]. | 2004 | J Dtsch Dermatol Ges | pmid:16281587 |
| Worret WI and Fluhr JW | [Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid]. | 2006 | J Dtsch Dermatol Ges | pmid:16638058 |
| Shemer A et al. | Azelaic acid (20%) cream in the treatment of acne vulgaris. | 2002 | J Eur Acad Dermatol Venereol | pmid:12046832 |
| Korting HC and Schöllmann C | Current topical and systemic approaches to treatment of rosacea. | 2009 | J Eur Acad Dermatol Venereol | pmid:19508315 |
| Elewski BE et al. | Rosacea - global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group. | 2011 | J Eur Acad Dermatol Venereol | pmid:20586834 |
| Stinco G et al. | Relationship between sebostatic activity, tolerability and efficacy of three topical drugs to treat mild to moderate acne. | 2007 | J Eur Acad Dermatol Venereol | pmid:17309452 |
| Mostafa FF et al. | Comparative study of some treatment modalities of rosacea. | 2009 | J Eur Acad Dermatol Venereol | pmid:18705632 |
| Kanitakis J | Linea fusca in a male adolescent successfully treated with azelaic acid. | 2008 | J Eur Acad Dermatol Venereol | pmid:18331308 |
| Gollnick H and Schramm M | Topical therapy in acne. | 1998 | J Eur Acad Dermatol Venereol | pmid:9891903 |
| Liao DC | Management of acne. | 2003 | J Fam Pract | pmid:12540312 |
| May D et al. | Clinical inquiries. What is the most effective treatment for acne rosacea? | 2011 | J Fam Pract | pmid:21301648 |
| Alevizos A et al. | Acne treatments: consider these options--and issues. | 2007 | J Fam Pract | pmid:17475157 |
| Punsalan T and Usatine RP | Red facial rash with "granitos". | 2005 | J Fam Pract | pmid:16144591 |
| Stewart JJ | Application of the PM6 method to modeling the solid state. | 2008 | J Mol Model | pmid:18449579 |
| Fujitani K et al. | Preparation of polycarboxylic acids by oxidative cleavage with oxygen / Co-Mn-Br system. | 2009 | J Oleo Sci | pmid:19915320 |
| Maru U et al. | [In vitro diffusion and skin penetration of azelaic preparations: study of correlations]. | 1982 May-Jun | J Pharm Belg | pmid:7131228 |
| Hinz DC | Efficiency improvement for sulfated ash determination by usage of a microwave muffle furnace. | 2007 | J Pharm Biomed Anal | pmid:17280812 |
| Gatti R et al. | Analysis of aliphatic dicarboxylic acids in pharmaceuticals and cosmetics by liquid chromatography (HPLC) with fluorescence detection. | 1995 | J Pharm Biomed Anal | pmid:9696574 |
| Solo AJ and Gardner JO | Agents for alkylating steroid hormone receptors. 3. Omega-substituted esters of 17-alpha-hydroxyprogesterone. | 1971 | J Pharm Sci | pmid:5115254 |
| Liu C et al. | Heterogeneous reaction of suspended phosmet particles with NO3 radicals. | 2011 | J Phys Chem A | pmid:21870875 |
| Hung HM et al. | Products and mechanisms of the reaction of oleic acid with ozone and nitrate radical. | 2005 | J Phys Chem A | pmid:16833788 |
| Page MM et al. | Ion chromatographic analysis of amines, alkanolamines, and associated anions in concrete. | 2005 | J Sep Sci | pmid:15835735 |
| Alzweiri M et al. | Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker. | 2013 | J Sep Sci | pmid:23893928 |
| Wu YH et al. | Effects of Chinese herbal medicine combined with He-Ne laser on lipoperoxide and superoxide dismutase in chloasma patients. | 2009 | J Tradit Chin Med | pmid:19894376 |
| Thiboutot D et al. | Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies. | 2003 | J. Am. Acad. Dermatol. | pmid:12789172 |
| Webster G | Combination azelaic acid therapy for acne vulgaris. | 2000 | J. Am. Acad. Dermatol. | pmid:10898830 |
| Sheth VM and Pandya AG | Melasma: a comprehensive update: part II. | 2011 | J. Am. Acad. Dermatol. | pmid:21920242 |
| Kameyama K et al. | Treatment of reticulate acropigmentation of Kitamura with azelaic acid. An immunohistochemical and electron microscopic study. | 1992 | J. Am. Acad. Dermatol. | pmid:1613143 |
| van Zuuren EJ et al. | Systematic review of rosacea treatments. | 2007 | J. Am. Acad. Dermatol. | pmid:17190628 |
| Nazzaro-Porro M | Azelaic acid. | 1987 | J. Am. Acad. Dermatol. | pmid:2963038 |
| Gatti S and Nini G | Treatment of reticulate acropigmentation of Kitamura with azelaic acid. | 1993 | J. Am. Acad. Dermatol. | pmid:8408814 |
| Maddin S | A comparison of topical azelaic acid 20% cream and topical metronidazole 0.75% cream in the treatment of patients with papulopustular rosacea. | 1999 | J. Am. Acad. Dermatol. | pmid:10365928 |