Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Clark AA et al. Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction. 2016 J. Leukoc. Biol. pmid:27154353
Samycia M and Lam JM Infantile acne. 2016 CMAJ pmid:27873756
Lim GH et al. Role of plasmodesmata and plasmodesmata localizing proteins in systemic immunity. 2016 Plant Signal Behav pmid:27645210
Lim GH et al. Plasmodesmata Localizing Proteins Regulate Transport and Signaling during Systemic Acquired Immunity in Plants. 2016 Cell Host Microbe pmid:27078071
Helfrich YR and Maier LM Topical and oral therapeutic approach to rosacea. 2016 Semin Cutan Med Surg pmid:27416312
Asai Y et al. Canadian Clinical Practice Guidelines for Rosacea. 2016 J Cutan Med Surg pmid:27207355
Le Lay C et al. Identification and quantification of antifungal compounds produced by lactic acid bacteria and propionibacteria. 2016 Int. J. Food Microbiol. pmid:27350657
Gupta G et al. Ivermectin 1% cream for rosacea. 2015 Jul-Aug Skin Therapy Lett. pmid:26382711
Gordy JW et al. Comparative Effectiveness of Potential Elicitors of Plant Resistance against Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) in Four Crop Plants. 2015 PLoS ONE pmid:26332833
Karimi AA et al. Improvement of tissue survival of skin flaps by 5α-reductase inhibitors: possible involvement of nitric oxide and inducible nitric oxide synthase. 2015 Iran. Biomed. J. pmid:25864816
van Zuuren EJ et al. Interventions for rosacea. 2015 Cochrane Database Syst Rev pmid:25919144
Ganzetti G et al. Rosacea: could topical azelaic acid and oral tetracyclines modify videocapillaroscopic pattern? 2014 Mar-Apr Skinmed pmid:24933858
Gołębiowski M et al. Antimicrobial activity of untypical lipid compounds in the cuticular and internal lipids of four fly species. 2014 J. Appl. Microbiol. pmid:24238211
Wittek F et al. Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. 2014 J. Exp. Bot. pmid:25114016
Wang C et al. Free radicals mediate systemic acquired resistance. 2014 Cell Rep pmid:24726369
Shariff A et al. Acne vulgaris in the context of complex medical co-morbities: the management of severe acne vulgaris in a female with retinitis pigmentosa - utilizing pulse dye laser in conjunction with medical therapy. 2014 Dermatol. Online J. pmid:24656277
Del Rosso JQ and Kircik LH Update on the management of rosacea: a status report on the current role and new horizons with topical azelaic acid. 2014 J Drugs Dermatol pmid:25607798
Del Rosso JQ et al. Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 5: a guide on the management of rosacea. 2014 Cutis pmid:24738094
Reis CP et al. Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment. 2014 Drug Dev Ind Pharm pmid:23480566
Vargas-Diez E et al. Azelaic acid in the treatment of acne in adult females: case reports. 2014 Skin Pharmacol Physiol pmid:24280645