Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Webster G Combination azelaic acid therapy for acne vulgaris. 2000 J. Am. Acad. Dermatol. pmid:10898830
Hermanns JF et al. Unraveling the patterns of subclinical pheomelanin-enriched facial hyperpigmentation: effect of depigmenting agents. 2000 Dermatology (Basel) pmid:11053913
Gutheil WG Application of hierarchical thermodynamic interactions to the protonation equilibria of organic polyprotic acids. 2000 Biophys. Chem. pmid:11152269
Malaisse WJ et al. Effects of aliphatic dioic acids and glycerol-1,2,3-tris(dodecanedioate) on D-glucose-stimulated insulin release in rat pancreatic islets. 2000 Br. J. Nutr. pmid:11177188
pmid:11333444
pmid:11451041
Koczorek M ["Cleansing, topical treatment, oral administration". Controlling acne]. 2001 MMW Fortschr Med pmid:11524979
Gollnick HP et al. Comparison of combined azelaic acid cream plus oral minocycline with oral isotretinoin in severe acne. 2001 Nov-Dec Eur J Dermatol pmid:11701404
Pérez-Bernal A et al. Management of facial hyperpigmentation. 2000 Sep-Oct Am J Clin Dermatol pmid:11702317
Vereecken P and Heenen M Recurrent lentigo maligna melanoma: regression associated with local azelaic acid 20%. 2002 Jan-Feb Int. J. Clin. Pract. pmid:11831841