| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Neoplasms | D013274 | 24 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Total
4
Itaconic acid
Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Itaconic acid?
Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Itaconic acid
PubChem Associated disorders and diseases
What pathways are associated with Itaconic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Itaconic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Itaconic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Itaconic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Itaconic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Itaconic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Itaconic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:27704840 | ||||
| Luan HH and Medzhitov R | Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense. | 2016 | Cell Metab. | pmid:27626199 |
| pmid:27577913 | ||||
| pmid:27543843 | ||||
| Hossain AH et al. | Rewiring a secondary metabolite pathway towards itaconic acid production in Aspergillus niger. | 2016 | Microb. Cell Fact. | pmid:27469970 |
| Itaconate and Inflammation, miRs in Zebrafish Embryos, and SHP2 Inhibitor. | 2016 | Cell Chem Biol | pmid:27447041 | |
| Lampropoulou V et al. | Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation. | 2016 | Cell Metab. | pmid:27374498 |
| Jiménez-Quero A et al. | Itaconic and Fumaric Acid Production from Biomass Hydrolysates by Aspergillus Strains. | 2016 | J. Microbiol. Biotechnol. | pmid:27291673 |
| pmid:27269589 | ||||
| pmid:27262296 | ||||
| pmid:27254798 | ||||
| pmid:27242313 | ||||
| Cordes T et al. | Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels. | 2016 | J. Biol. Chem. | pmid:27189937 |
| pmid:27102125 | ||||
| Ferreira JA et al. | Waste biorefineries using filamentous ascomycetes fungi: Present status and future prospects. | 2016 | Bioresour. Technol. | pmid:26996263 |
| Xie X et al. | "Nanofiltration" Enabled by Super-Absorbent Polymer Beads for Concentrating Microorganisms in Water Samples. | 2016 | Sci Rep | pmid:26876979 |
| pmid:26851896 | ||||
| Naujoks J et al. | IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid. | 2016 | PLoS Pathog. | pmid:26829557 |
| pmid:26704570 | ||||
| Meiser J et al. | Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression. | 2016 | J. Biol. Chem. | pmid:26679997 |
| pmid:26658228 | ||||
| Higuchi A et al. | Long-term xeno-free culture of human pluripotent stem cells on hydrogels with optimal elasticity. | 2015 | Sci Rep | pmid:26656754 |
| Geiser E et al. | Ustilago maydis produces itaconic acid via the unusual intermediate trans-aconitate. | 2016 | Microb Biotechnol | pmid:26639528 |
| pmid:26572824 | ||||
| pmid:26384571 | ||||
| Németh B et al. | Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. | 2016 | FASEB J. | pmid:26358042 |
| Li Z et al. | Copper-Catalyzed Dimerization/Cyclization of Itaconates. | 2015 | Molecules | pmid:26287154 |
| pmid:26275817 | ||||
| pmid:26249213 | ||||
| pmid:26210102 | ||||
| pmid:26208692 | ||||
| Yamamoto K et al. | Challenges in the production of itaconic acid by metabolically engineered Escherichia coli. | 2015 | Bioengineered | pmid:26176321 |
| Farmer TJ et al. | Synthesis of Unsaturated Polyester Resins from Various Bio-Derived Platform Molecules. | 2015 | Int J Mol Sci | pmid:26147423 |
| pmid:26100077 | ||||
| pmid:26086434 | ||||
| pmid:26078111 | ||||
| Kronen M et al. | Mesaconase Activity of Class I Fumarase Contributes to Mesaconate Utilization by Burkholderia xenovorans. | 2015 | Appl. Environ. Microbiol. | pmid:26070669 |
| pmid:25974697 | ||||
| pmid:25683741 | ||||
| pmid:25665779 | ||||
| pmid:25651876 | ||||
| pmid:25557737 | ||||
| pmid:25554635 | ||||
| pmid:25468427 | ||||
| Okamoto S et al. | Production of itaconic acid using metabolically engineered Escherichia coli. | 2014 | J. Gen. Appl. Microbiol. | pmid:25420424 |
| pmid:25277412 | ||||
| pmid:25213913 | ||||
| Huang X et al. | Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain. | 2014 | Microb. Cell Fact. | pmid:25162789 |
| Huang X et al. | Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus. | 2014 | Microb. Cell Fact. | pmid:25162619 |
| pmid:25045161 |