MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Weight Gain | D015430 | 101 associated lipids |
Hyperplasia | D006965 | 34 associated lipids |
Stomach Neoplasms | D013274 | 24 associated lipids |
Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.
To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Itaconic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Weight Gain | D015430 | 101 associated lipids |
Hyperplasia | D006965 | 34 associated lipids |
Stomach Neoplasms | D013274 | 24 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Boruta T and Bizukojc M | Production of lovastatin and itaconic acid by Aspergillus terreus: a comparative perspective. | 2017 | World J. Microbiol. Biotechnol. | pmid:28102516 |
Yin X et al. | Pgas, a Low-pH-Induced Promoter, as a Tool for Dynamic Control of Gene Expression for Metabolic Engineering of Aspergillus niger. | 2017 | Appl. Environ. Microbiol. | pmid:28087530 |
Shin WS et al. | Enhanced Production of Itaconic Acid through Development of Transformed Fungal Strains of Aspergillus terreus. | 2017 | J. Microbiol. Biotechnol. | pmid:27974733 |
Rau MH et al. | Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals. | 2016 | Microb. Cell Fact. | pmid:27737709 |
Luan HH and Medzhitov R | Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense. | 2016 | Cell Metab. | pmid:27626199 |
Hossain AH et al. | Rewiring a secondary metabolite pathway towards itaconic acid production in Aspergillus niger. | 2016 | Microb. Cell Fact. | pmid:27469970 |
Itaconate and Inflammation, miRs in Zebrafish Embryos, and SHP2 Inhibitor. | 2016 | Cell Chem Biol | pmid:27447041 | |
Lampropoulou V et al. | Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation. | 2016 | Cell Metab. | pmid:27374498 |
Jiménez-Quero A et al. | Itaconic and Fumaric Acid Production from Biomass Hydrolysates by Aspergillus Strains. | 2016 | J. Microbiol. Biotechnol. | pmid:27291673 |
Németh B et al. | Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. | 2016 | FASEB J. | pmid:26358042 |