Itaconic acid

Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.

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Introduction

To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Itaconic acid?

Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Itaconic acid

PubChem Associated disorders and diseases

What pathways are associated with Itaconic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Itaconic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Itaconic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Itaconic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Itaconic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Itaconic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Itaconic acid

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Authors Title Published Journal PubMed Link
LARSEN H and EIMHJELLEN KE The mechanism of itaconic acid formation by Aspergillus terreus. 1. The effect of acidity. 1955 Biochem. J. pmid:14363197
COOPER RA et al. THE UTILIZATION OF ACONATE AND ITACONATE BY MICROCOCCUS SP. 1965 Biochem. J. pmid:14342240
NAGAI J STUDIES ON ITACONATE METABOLISM. II. CITRAMALATE METABOLISM IN PSEUDOMONAS FLUORESCENS GROWN ON ITACONATE. 1963 J. Biochem. pmid:14056350
KATSUKI H et al. Metabolism of methyl succinate in Pseudomonas fluorescens grown on itaconate. 1963 J. Biochem. pmid:13958451
NAGAI J Studies on itaconate metabolism. I. Itaconyl-Co-A synthesizing reaction in cell-free extracts of Pseudomonas fluorescens. 1963 J. Biochem. pmid:13937094
WANG SF et al. The pathway of itaconate metabolism by liver mitochondria. 1961 J. Biol. Chem. pmid:13783048
Kautola H et al. Continuous itaconic acid production by immobilized biocatalysts. 1990 J. Biotechnol. pmid:1366363
ADLER J et al. The metabolism of itaconic acid by liver mitochondria. 1957 J. Biol. Chem. pmid:13502348
BENTLEY R and THIESSEN CP Biosynthesis of itaconic acid in Aspergillus terreus. III. The properties and reaction mechanism of cis-aconitic acid decarboxylase. 1957 J. Biol. Chem. pmid:13438855
BENTLEY R and THIESSEN CP Biosynthesis of itaconic acid in Aspergillus terreus. II. Early stages in glucose dissimilation and the role of citrate. 1957 J. Biol. Chem. pmid:13438854