Itaconic acid

Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.

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Introduction

To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Itaconic acid?

Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Itaconic acid

PubChem Associated disorders and diseases

What pathways are associated with Itaconic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Itaconic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Itaconic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Itaconic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Itaconic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Itaconic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Itaconic acid

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Authors Title Published Journal PubMed Link
Kyzas GZ et al. Poly(itaconic acid)-grafted chitosan adsorbents with different cross-linking for Pb(II) and Cd(II) uptake. 2014 Langmuir pmid:24011255
Moynihan MM and Murkin AS Cysteine is the general base that serves in catalysis by isocitrate lyase and in mechanism-based inhibition by 3-nitropropionate. 2014 Biochemistry pmid:24354272
Zhang M et al. The preparation of magnetic molecularly imprinted nanoparticles for the recognition of bovine hemoglobin. 2014 Talanta pmid:24468385
Sasikaran J et al. Bacterial itaconate degradation promotes pathogenicity. 2014 Nat. Chem. Biol. pmid:24657929
Cheah HL et al. Inhibitors of the glyoxylate cycle enzyme ICL1 in Candida albicans for potential use as antifungal agents. 2014 PLoS ONE pmid:24781056
Milašinović N et al. Catalyzed ester synthesis using Candida rugosa lipase entrapped by poly(N-isopropylacrylamide-co-itaconic acid) hydrogel. 2014 ScientificWorldJournal pmid:24701136
Gao Q et al. Relationship between morphology and itaconic acid production by Aspergillus terreus. 2014 J. Microbiol. Biotechnol. pmid:24169454
Blumhoff M et al. Six novel constitutive promoters for metabolic engineering of Aspergillus niger. 2013 Appl. Microbiol. Biotechnol. pmid:22707054
Calles JA et al. Novel bioadhesive hyaluronan-itaconic acid crosslinked films for ocular therapy. 2013 Int J Pharm pmid:23911915
Li A et al. A systems biology approach for the identification of target genes for the improvement of itaconic acid production in Aspergillus species. 2013 BMC Res Notes pmid:24304666