Itaconic acid

Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.

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Introduction

To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Itaconic acid?

Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Itaconic acid

PubChem Associated disorders and diseases

What pathways are associated with Itaconic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Itaconic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Itaconic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Itaconic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Itaconic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Itaconic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Itaconic acid

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Authors Title Published Journal PubMed Link
Hillier S and Charnetzky WT Glyoxylate bypass enzymes in Yersinia species and multiple forms of isocitrate lyase in Yersinia pestis. 1981 J. Bacteriol. pmid:7462147
Bonnarme P et al. Itaconate biosynthesis in Aspergillus terreus. 1995 J. Bacteriol. pmid:7768868
Dolle RE et al. Synthesis of novel thiol-containing citric acid analogues. Kinetic evaluation of these and other potential active-site-directed and mechanism-based inhibitors of ATP citrate lyase. 1995 J. Med. Chem. pmid:7853346
Lee YS and Jang JJ Potent promoting activity of dimethylitaconate on gastric carcinogenesis induced by N-methylnitrosourea. 1994 Cancer Lett. pmid:7954334
Lyngstad M and Grasdalen H A new NMR airlift bioreactor used in 31P-NMR studies of itaconic acid producing Aspergillus terreus. 1993 J. Biochem. Biophys. Methods pmid:8227940
Miyazaki K et al. Polymeric calcium phosphate cements: analysis of reaction products and properties. 1993 Dent Mater pmid:8299869
Maloney AP and Attwood MM The production of itaconic acid and tetronic acids with respect to the growth cycle of Penicillium charlesii. 1976 J. Gen. Microbiol. pmid:8588
Kao EC et al. Preparation of glass ionomer cement using N-acryloyl-substituted amino acid monomers--evaluation of physical properties. 1996 Dent Mater pmid:8598250
Blanco MD et al. 5-Fluorouracil release from copolymeric hydrogels of itaconic acid monoester. I. Acrylamide-co-monomethyl itaconate. 1996 Biomaterials pmid:8718965
Blanco MD et al. Release of 5-fluorouracil from poly(acrylamide-co-monopropyl itaconate) hydrogels. 1996 J. Chromatogr. B, Biomed. Appl. pmid:8798904
KaradaÄŸ E et al. In vitro swelling studies and preliminary biocompatibility evaluation of acrylamide-based hydrogels. 1996 Biomaterials pmid:8962950