Itaconic acid

Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.

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Introduction

To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Itaconic acid?

Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Itaconic acid

PubChem Associated disorders and diseases

What pathways are associated with Itaconic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Itaconic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Itaconic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Itaconic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Itaconic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Itaconic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Itaconic acid

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Authors Title Published Journal PubMed Link
Hillier S and Charnetzky WT Glyoxylate bypass enzymes in Yersinia species and multiple forms of isocitrate lyase in Yersinia pestis. 1981 J. Bacteriol. pmid:7462147
O'Connell BT and Paznokas JL Glyoxylate cycle in Mucor racemosus. 1980 J. Bacteriol. pmid:7400097
Schloss JV and Cleland WW Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue. 1982 Biochemistry pmid:7126549
Leskovar P et al. [Contribution to the problem of preventing recurrences of oxalate and phosphate urinary caluli: active modification of citrate excretion and Ca++-binding capacity in the urine of Wistar rats]. 1982 Z Urol Nephrol pmid:7102130
Crisp S et al. Glass-ionomer cement formulations. II. The synthesis of novel polycarobxylic acids. 1980 J. Dent. Res. pmid:6929290
Shimamoto G and Berk RS Taurine catabolism. III. Evidence for the participation of the glyoxylate cycle. 1980 Biochim. Biophys. Acta pmid:6774766
Patel TR and McFadden BA Caenorhabditis elegans and Ascaris suum: inhibition of isocitrate lyase by itaconate. 1978 Exp. Parasitol. pmid:658222
Rittenhouse JW and McFadden BA Inhibition of isocitrate lyase from Pseudomonas indigofera by itaconate. 1974 Arch. Biochem. Biophys. pmid:4852477
Jakubowska J and Metodiewa D Studies on the metabolic pathway for itatartaric acid formation by Aspergillus terreus. II. Use of (-)citramalate, citraconate and itaconate by cell-free extracts. 1974 Acta Microbiol Pol B pmid:4836927
Watts DC 13C NMR spectroscopic analysis of poly(electrolyte) cement liquids. 1979 J. Biomed. Mater. Res. pmid:438227