Itaconic acid

Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.

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Introduction

To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Itaconic acid?

Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Itaconic acid

PubChem Associated disorders and diseases

What pathways are associated with Itaconic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Itaconic acid?

Related references are published most in these journals:

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What functions are associated with Itaconic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Itaconic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Itaconic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Itaconic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Itaconic acid

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Authors Title Published Journal PubMed Link
pmid:
Itoh T et al. Effect of contamination and etching on enamel bond strength of new light-cured glass ionomer cements. 1999 Angle Orthod pmid:10515143
Tsao GT et al. Production of multifunctional organic acids from renewable resources. 1999 Adv. Biochem. Eng. Biotechnol. pmid:10533437
Cehreli ZC and Altay N Effects of a nonrinse conditioner and 17% ethylenediaminetetraacetic acid on the etch pattern of intact human permanent enamel. 2000 Angle Orthod pmid:10730672
Li W et al. Synthesis of chiral hydroxyl phospholanes from D-mannitol and their use in asymmetric catalytic reactions. 2000 J. Org. Chem. pmid:10843636
Stahmann KP et al. Three biotechnical processes using Ashbya gossypii, Candida famata, or Bacillus subtilis compete with chemical riboflavin production. 2000 Appl. Microbiol. Biotechnol. pmid:10855708
Chen D [Physical properties of apatite bone cement]. 2000 Sheng Wu Yi Xue Gong Cheng Xue Za Zhi pmid:10879182
Baures PW et al. Hydrogen bonding isosteres: bimolecular carboxylic acid and amine-N-oxide interactions mediated via CH...O hydrogen bonds. 2000 Bioorg. Med. Chem. pmid:10976507
Riscaldati E et al. Effect of pH and stirring rate on itaconate production by Aspergillus terreus. 2000 J. Biotechnol. pmid:11051419
Vaidya AA et al. Thermoprecipitation of lysozyme from egg white using copolymers of N-isopropylacrylamide and acidic monomers. 2001 J. Biotechnol. pmid:11278034
Iványi I et al. The effect of acid etching on vascular diameter of pulp-vessels in rat incisor (vitalmicroscopic study). 2001 May-Jun Oper Dent pmid:11357566
pmid:11442049
Pashley DH and Tay FR Aggressiveness of contemporary self-etching adhesives. Part II: etching effects on unground enamel. 2001 Dent Mater pmid:11445211
Willke T and Vorlop KD Biotechnological production of itaconic acid. 2001 Appl. Microbiol. Biotechnol. pmid:11548996
Sen M and Yakar A Controlled release of antifungal drug terbinafine hydrochloride from poly(N-vinyl 2-pyrrolidone/itaconic acid) hydrogels. 2001 Int J Pharm pmid:11576766
pmid:11695919
Wallach JA and Huang SJ Copolymers of itaconic anhydride and methacrylate-terminated poly(lactic acid) macromonomers. 2000 Biomacromolecules pmid:11710097
del Río JC et al. Identification of a novel series of alkylitaconic acids in wood cultures of Ceriporiopsis subvermispora by gas chromatography/mass spectrometry. 2002 Rapid Commun. Mass Spectrom. pmid:11754248
pmid:11791342
pmid:11888209
pmid:12054265
Reddy CS and Singh RP Enhanced production of itaconic acid from corn starch and market refuse fruits by genetically manipulated Aspergillus terreus SKR10. 2002 Bioresour. Technol. pmid:12146646
Bashir W et al. Retention of alkali, alkaline earth and transition metals on an itaconic acid cation-exchange column. Eluent pH, ionic strength and temperature effects upon selectivity. 2002 J Chromatogr A pmid:12198839
Watanabe T et al. A selective lignin-degrading fungus, Ceriporiopsis subvermispora, produces alkylitaconates that inhibit the production of a cellulolytic active oxygen species, hydroxyl radical in the presence of iron and H(2)O(2). 2002 Biochem. Biophys. Res. Commun. pmid:12359241
pmid:12361251
Berg IA et al. Inhibition of acetate and propionate assimilation by itaconate via propionyl-CoA carboxylase in isocitrate lyase-negative purple bacterium Rhodospirillum rubrum. 2002 FEMS Microbiol. Lett. pmid:12423751
Enoki M et al. Chemical synthesis, iron redox interactions and charge transfer complex formation of alkylitaconic acids from Ceriporiopsis subvermispora. 2002 Chem. Phys. Lipids pmid:12426072
pmid:12465915
Tang W et al. Asymmetric hydrogenation of itaconic acid and enol acetate derivatives with the Rh-TangPhos catalyst. 2003 Org. Lett. pmid:12529141
Lizos DE and Murphy JA Concise synthesis of (+/-)-horsfiline and (+/-)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides. 2003 Org. Biomol. Chem. pmid:12929397
BENTLEY R and THIESSEN CP Biosynthesis of itaconic acid in Aspergillus terreus. I. Tracer studies with C14-labeled substrates. 1957 J. Biol. Chem. pmid:13438853
BENTLEY R and THIESSEN CP Biosynthesis of itaconic acid in Aspergillus terreus. II. Early stages in glucose dissimilation and the role of citrate. 1957 J. Biol. Chem. pmid:13438854
BENTLEY R and THIESSEN CP Biosynthesis of itaconic acid in Aspergillus terreus. III. The properties and reaction mechanism of cis-aconitic acid decarboxylase. 1957 J. Biol. Chem. pmid:13438855
ADLER J et al. The metabolism of itaconic acid by liver mitochondria. 1957 J. Biol. Chem. pmid:13502348
Kautola H et al. Continuous itaconic acid production by immobilized biocatalysts. 1990 J. Biotechnol. pmid:1366363
WANG SF et al. The pathway of itaconate metabolism by liver mitochondria. 1961 J. Biol. Chem. pmid:13783048
NAGAI J Studies on itaconate metabolism. I. Itaconyl-Co-A synthesizing reaction in cell-free extracts of Pseudomonas fluorescens. 1963 J. Biochem. pmid:13937094
KATSUKI H et al. Metabolism of methyl succinate in Pseudomonas fluorescens grown on itaconate. 1963 J. Biochem. pmid:13958451
NAGAI J STUDIES ON ITACONATE METABOLISM. II. CITRAMALATE METABOLISM IN PSEUDOMONAS FLUORESCENS GROWN ON ITACONATE. 1963 J. Biochem. pmid:14056350
COOPER RA et al. THE UTILIZATION OF ACONATE AND ITACONATE BY MICROCOCCUS SP. 1965 Biochem. J. pmid:14342240
LARSEN H and EIMHJELLEN KE The mechanism of itaconic acid formation by Aspergillus terreus. 1. The effect of acidity. 1955 Biochem. J. pmid:14363197
EIMHJELLEN KE and LARSEN H The mechanism of itaconic acid formation by Aspergillus terreus. 2. The effect of substrates and inhibitors. 1955 Biochem. J. pmid:14363198
MARTIN WR et al. Noninductive metabolism of itaconic acid by Pseudomonas and Salmonella species. 1961 J. Bacteriol. pmid:14470458
Amirta R et al. Ceriporic acid C, a hexadecenylitaconate produced by a lignin-degrading fungus, Ceriporiopsis subvermispora. 2003 Chem. Phys. Lipids pmid:14623447
Wood J and Turner PH Monitoring of itaconic acid hydrogenation in a trickle bed reactor using fiber-optic coupled near-infrared spectroscopy. 2003 Appl Spectrosc pmid:14658621
Katime I et al. Specific interactions study in complexes of poly(mono-n-alkyl itaconates) with tertiary polyamides. 2003 Appl Spectrosc pmid:14658662
BOOTH AN et al. The inhibitory effects of itaconic acid in vitro and in vivo. 1952 J. Biol. Chem. pmid:14946179
Nordon A et al. Monitoring of a heterogeneous reaction by acoustic emission. 2004 Analyst pmid:15116241
TaÅŸdelen B et al. Preparation of poly(N-isopropylacrylamide/itaconic acid) copolymeric hydrogels and their drug release behavior. 2004 Int J Pharm pmid:15196639
Lin YH et al. Intracellular expression of Vitreoscilla hemoglobin in Aspergillus terreus to alleviate the effect of a short break in aeration during culture. 2004 Biotechnol. Lett. pmid:15218381
pmid:15289678
pmid:15387549
Zhang X et al. Multi-maleimides bearing electron-donating chromophores: reversible fluorescence and aggregation behavior. 2004 J. Am. Chem. Soc. pmid:15453717
pmid:15556350
Sakai A et al. Itaconate reduces visceral fat by inhibiting fructose 2,6-bisphosphate synthesis in rat liver. 2004 Nov-Dec Nutrition pmid:15561490
Meng Z and Sode K The molecular reaction vessels for a transesterification process created by molecular imprinting technique. 2005 May-Jun J. Mol. Recognit. pmid:15593236
Iqbal M and Saeed A Novel method for cell immobilization and its application for production of organic acid. 2005 Lett. Appl. Microbiol. pmid:15715641
Stanojević M et al. Swelling behavior and mechanical properties of poly(acrylamide-co-itaconic acid) hydrogels and their semi-IPNS with poly(ethylene glycol). 2005 J Control Release pmid:15719500
pmid:15730312
De TK et al. Polycarboxylic acid nanoparticles for ophthalmic drug delivery: an ex vivo evaluation with human cornea. 2004 J Microencapsul pmid:15799540
Stanojević M et al. Swelling and paracetamol release studies of poly(acrylamide-co-itaconic acid) hydrogels. 2005 J Control Release pmid:15832461
Brenna O Itaconic acid carrier ampholytes for isoelectric focusing. 1977 J. Chromatogr. pmid:16028
Warnecke T and Gill RT Organic acid toxicity, tolerance, and production in Escherichia coli biorefining applications. 2005 Microb. Cell Fact. pmid:16122392
Shekhawat D et al. Process model and economic analysis of itaconic acid production from dimethyl succinate and formaldehyde. 2006 Bioresour. Technol. pmid:16171691
He BF et al. Efficient conversion of itaconic acid to (S)-(+)-citramalic acid by Alcaligenes xylosoxydans IL142. 2000 J. Biosci. Bioeng. pmid:16232765
pmid:16233265
Tsukamoto S et al. Hexylitaconic acid: a new inhibitor of p53-HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp. 2006 Bioorg. Med. Chem. Lett. pmid:16246554
Stanojević M et al. An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media. 2006 Jan-Feb Drug Deliv pmid:16401587
Nordon A et al. Factors affecting broadband acoustic emission measurements of a heterogeneous reaction. 2006 Analyst pmid:16440100
pmid:16477123
Serrano I et al. Catalytic ability of a cationic Ru(II) monochloro complex for the asymmetric hydrogenation of dimethyl itaconate and enamides. 2006 Inorg Chem pmid:16529487
North R et al. Synthesis of UV-absorbing and fluorescent carrier ampholyte mixtures and their application for the determination of the operational pH values of buffering membranes used in isoelectric trapping separations. 2006 J Chromatogr A pmid:16626722
Khan FR and McFadden BA Enzyme Profiles in Seedling Development and the Effect of Itaconate, an Isocitrate Lyase-directed Reagent. 1979 Plant Physiol. pmid:16660938
Friedmann S et al. Properties of succinyl-coenzyme A:D-citramalate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus. 2006 J. Bacteriol. pmid:16952935
pmid:16996731
pmid:17014142
Cakir T et al. Integration of metabolome data with metabolic networks reveals reporter reactions. 2006 Mol. Syst. Biol. pmid:17016516
Daniel J et al. AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis. 2007 J. Bacteriol. pmid:17114269
Zhang W and Zhang X Highly enantioselective hydrogenation of alpha-dehydroamino esters and itaconates with triphosphorous bidentate ligands and the unprecedented solvent effect thereof. 2007 J. Org. Chem. pmid:17253827
pmid:17295365
Ohashi Y et al. Redox silencing of the Fenton reaction system by an alkylitaconic acid, ceriporic acid B produced by a selective lignin-degrading fungus, Ceriporiopsis subvermispora. 2007 Org. Biomol. Chem. pmid:17315072
Aliverdieva DA et al. Topography of the active site of the Saccharomyces cerevisiae plasmalemmal dicarboxylate transporter studied using lipophilic derivatives of its substrates. 2007 Biochemistry Mosc. pmid:17447879
Dwiarti L et al. Itaconic acid production using sago starch hydrolysate by Aspergillus terreus TN484-M1. 2007 Bioresour. Technol. pmid:17451943
Park EY et al. Isolation of Ashbya gossypii mutant for an improved riboflavin production targeting for biorefinery technology. 2007 J. Appl. Microbiol. pmid:17650208
Lai LS et al. Effects of lactose and glucose on production of itaconic acid and lovastatin by Aspergillus terreus ATCC 20542. 2007 J. Biosci. Bioeng. pmid:17697977
pmid:17705446
Xi Y et al. [The drug release properties of poly (acrylamide-co-itaconate-vinylbenzylglycosylallylamide) hydrogels]. 2007 Sheng Wu Yi Xue Gong Cheng Xue Za Zhi pmid:17713271
Fox ME et al. Bis-(2,5-diphenylphospholanes) with sp2 carbon linkers: synthesis and application in asymmetric hydrogenation. 2008 J. Org. Chem. pmid:17949042
pmid:18031047
Miller WG et al. The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri. 2007 PLoS ONE pmid:18159241
Pulat M et al. Fluconazole release from hydrogels including acrylamide-acrylic acid-itaconic acid, and their microbiological interactions. 2008 J Biomater Sci Polym Ed pmid:18237492
Pascale M et al. Use of itaconic acid-based polymers for solid-phase extraction of deoxynivalenol and application to pasta analysis. 2008 Anal. Chim. Acta pmid:18261508
Wang N et al. Sesterterpenoids from the sponge Sarcotragus sp. 2008 J. Nat. Prod. pmid:18341287
Chang YH et al. Dihydroxystyrene metabolites from an association of the sponges Poecillastra wondoensis and Jaspis sp. 2008 J. Nat. Prod. pmid:18407691
Moshaverinia A et al. Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties. 2008 Dent Mater pmid:18433855
van Beilen JB and Poirier Y Production of renewable polymers from crop plants. 2008 Plant J. pmid:18476872
Ko YH et al. Substrate-decreased modification by diethyl pyrocarbonate of two histidines in isocitrate lyase from Escherichia coli. 1991 Biochemistry pmid:1854747
Kanamasa S et al. Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus. 2008 Appl. Microbiol. Biotechnol. pmid:18584171
pmid:18640084
Uysal A et al. Hemoglobin recognition of molecularly imprinted hydrogels prepared at different pHs. 2008 Anal. Chim. Acta pmid:18721547