| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nagano K et al. | A novel phospholipase C delta4 (PLCdelta4) splice variant as a negative regulator of PLC. | 1999 | J. Biol. Chem. | pmid:9915823 |
| Hinchliffe KA et al. | PIPkins1, their substrates and their products: new functions for old enzymes. | 1998 | Biochim. Biophys. Acta | pmid:9838059 |
| Cooke FT et al. | The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. | 1998 | Curr. Biol. | pmid:9811604 |
| Baukrowitz T et al. | PIP2 and PIP as determinants for ATP inhibition of KATP channels. | 1998 | Science | pmid:9804555 |
| Shyng SL and Nichols CG | Membrane phospholipid control of nucleotide sensitivity of KATP channels. | 1998 | Science | pmid:9804554 |
| Ryningen A et al. | Elevation of cyclic AMP decreases phosphoinositide turnover and inhibits thrombin-induced secretion in human platelets. | 1998 | Biochim. Biophys. Acta | pmid:9795233 |
| Guilherme A et al. | A novel phosphorylated lipid counteracts activation of the renal plasma membrane (Ca2+ + Mg2+)ATPase by endogenous phosphatidylinositol-4-phosphate. | 1998 | Biosci. Rep. | pmid:9743476 |
| Wang PY et al. | Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide. | 1998 | J. Biol. Chem. | pmid:9733716 |
| Stevenson JM et al. | A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. | 1998 | J. Biol. Chem. | pmid:9712908 |
| Lukowski S et al. | Fodrin inhibits phospholipases A2, C, and D by decreasing polyphosphoinositide cell content. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9675127 |
| Waugh MG et al. | Phosphatidylinositol 4-phosphate synthesis in immunoisolated caveolae-like vesicles and low buoyant density non-caveolar membranes. | 1998 | J. Biol. Chem. | pmid:9642278 |
| Linseman DA et al. | Cytoskeletal and phosphoinositide requirements for muscarinic receptor signaling to focal adhesion kinase and paxillin. | 1998 | J. Neurochem. | pmid:9489713 |
| Willars GB et al. | Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells. | 1998 | J. Biol. Chem. | pmid:9478953 |
| Hollenback D and Glomset JA | On the relation between a stearoyl-specific transacylase from bovine testis membranes and a copurifying acyltransferase. | 1998 | Biochemistry | pmid:9425058 |
| Rameh LE et al. | A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. | 1997 | Nature | pmid:9367159 |
| Cheng CH | In vitro and in vivo inhibitory actions of morin on rat brain phosphatidylinositolphosphate kinase activity. | 1997 | Life Sci. | pmid:9366511 |
| Müller E et al. | Dependence on intracellular Ca2+ on mass and turnover of phosphoinositides and phosphatidate in human erythrocytes. | 1997 | Biol. Chem. | pmid:9348118 |
| Miyazawa A et al. | Immunohistochemical analysis of signal transduction system in developing rat Purkinje cell by using antibodies for signaling molecules. | 1993 | Ann. N. Y. Acad. Sci. | pmid:9137614 |
| Sun SH et al. | Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells. | 1997 | Lipids | pmid:9076664 |
| Mani I et al. | Increased formation of phosphatidylinositol-4-phosphate in human platelets stimulated with lysophosphatidic acid. | 1996 | Lipids | pmid:8972459 |
| Isenberg G et al. | Probing phosphatidylinositolphosphates and adenosinenucleotides on talin nucleated actin polymerization. | 1996 | FEBS Lett. | pmid:8955371 |
| Santavenere E et al. | Sensitivity of Daudi cells to tumor necrosis factor alpha: early changes in polyphosphoinositide metabolism. | 1996 | Cell Biol. Int. | pmid:8948126 |
| Tong W and Sun GY | Effects of ethanol on phosphorylation of lipids in rat synaptic plasma membranes. | 1996 | Alcohol. Clin. Exp. Res. | pmid:8947307 |
| Salim K et al. | Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. | 1996 | EMBO J. | pmid:8947047 |
| Filtz TM et al. | Purification and G protein subunit regulation of a phospholipase C-beta from Xenopus laevis oocytes. | 1996 | J. Biol. Chem. | pmid:8940109 |
| Loijens JC et al. | The phosphatidylinositol 4-phosphate 5-kinase family. | 1996 | Adv. Enzyme Regul. | pmid:8869744 |
| DebBurman SK et al. | G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. | 1996 | J. Biol. Chem. | pmid:8798423 |
| Molz L et al. | Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain. | 1996 | J. Biol. Chem. | pmid:8662856 |
| Ivanenkov VV et al. | Interaction of S100a0 protein with the actin capping protein, CapZ: characterization of a putative S100a0 binding site in CapZ alpha-subunit. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8660341 |
| Brearley CA and Hanke DE | Pathway of synthesis of 3,4- and 4,5-phosphorylated phosphatidylinositols in the duckweed Spirodela polyrhiza L. | 1993 | Biochem. J. | pmid:8382475 |
| Tran D et al. | Cellular distribution of polyphosphoinositides in rat hepatocytes. | 1993 | Cell. Signal. | pmid:8312134 |
| Flanagan CA et al. | Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. | 1993 | Science | pmid:8248783 |
| Björk J and Backman L | Sodium selenite as modulator of red cell shape. | 1994 | Biochim. Biophys. Acta | pmid:8155668 |
| James SR et al. | Interfacial hydrolysis of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate by turkey erythrocyte phospholipase C. | 1994 | Biochem. J. | pmid:8135761 |
| Ohnuma M and Mabuchi I | 45K actin filament-severing protein from sea urchin eggs: interaction with phosphatidylinositol-4,5-bisphosphate. | 1993 | J. Biochem. | pmid:8113226 |
| Tong W and Sun GY | Phosphorylation of lipids in rat primary glial cells and immortalized astrocytes (DITNC). | 1994 | Lipids | pmid:8090058 |
| Zeng XT et al. | Electrogenic and phosphatidylinositol-4-monophosphate-stimulated Cl- transport by Cl- pump in the rat brain. | 1994 | Brain Res. | pmid:8019845 |
| Girton RA et al. | 15-HETE: selective incorporation into inositol phospholipids of MDCK cells. | 1994 | Kidney Int. | pmid:8007600 |
| Roldan ER et al. | Exocytosis in spermatozoa in response to progesterone and zona pellucida. | 1994 | Science | pmid:7985030 |
| Pacini L et al. | Effects of perphenazine on the metabolism of inositol phospholipids in SK-N-BE(2) human neuroblastoma cells. | 1994 | Biochem. Pharmacol. | pmid:7980631 |
| Starling AP et al. | Phosphatidylinositol 4-phosphate increases the rate of dephosphorylation of the phosphorylated Ca(2+)-ATPase. | 1995 | J. Biol. Chem. | pmid:7782308 |
| Martelli AM et al. | Inositides in nuclei of Friend cells: changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation. | 1995 | Cell. Signal. | pmid:7756111 |
| Apgar JR | Activation of protein kinase C in rat basophilic leukemia cells stimulates increased production of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: correlation with actin polymerization. | 1995 | Mol. Biol. Cell | pmid:7749199 |
| Stack JH et al. | Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. | 1995 | J. Cell Biol. | pmid:7721937 |
| Vickers JD | Extraction of polyphosphoinositides from platelets: comparison of a two-step procedure with a common single-step extraction procedure. | 1995 | Anal. Biochem. | pmid:7710110 |
| Ding KH and Liang NC | Inhibition of 5'-chloro-5'-deoxyadenosine on phosphoinositide and protein phosphorylation in swine platelets. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7660821 |
| Tooke NE et al. | Ca2+-sensitive phosphatidylinositol 4-phosphate metabolism in a rat beta-cell tumour. | 1984 | Biochem. J. | pmid:6331389 |
| Seyfred MA and Wells WW | Subcellular incorporation of 32P into phosphoinositides and other phospholipids in isolated hepatocytes. | 1984 | J. Biol. Chem. | pmid:6330069 |
| Vickers JD et al. | Changes in the platelet phosphoinositides during the first minute after stimulation of washed rabbit platelets with thrombin. | 1984 | Biochem. J. | pmid:6326756 |
| Hawkins PT et al. | Analysis of the metabolic turnover of the individual phosphate groups of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate. Validation of novel analytical techniques by using 32P-labelled lipids from erythrocytes. | 1984 | Biochem. J. | pmid:6326746 |
| Wassef NM et al. | Suppression of phagocytic function and phospholipid metabolism in macrophages by phosphatidylinositol liposomes. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6326135 |
| Graff G et al. | Possible regulation of phospholipase C activity in human platelets by phosphatidylinositol 4',5'-bisphosphate. | 1984 | Arch. Biochem. Biophys. | pmid:6320736 |
| Creba JA et al. | Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones. | 1983 | Biochem. J. | pmid:6309153 |
| Volpi M et al. | Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6303343 |
| Downes P and Michell RH | Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: lipids in search of a function. | 1982 | Cell Calcium | pmid:6297743 |
| Deshmukh DS et al. | Mutual stimulation by phosphatidylinositol-4-phosphate and myelin basic protein of their phosphorylation by the kinases solubilized from rat brain myelin. | 1984 | Life Sci. | pmid:6198580 |
| Smith CD and Wells WW | Characterization of a phosphatidylinositol 4-phosphate-specific phosphomonoesterase in rat liver nuclear envelopes. | 1984 | Arch. Biochem. Biophys. | pmid:6097190 |
| Farkas G et al. | Cyclic AMP-dependent protein kinase stimulates the phosphorylation of phosphatidylinositol to phosphatidylinositol-4-monophosphate in a plasma membrane preparation from pig granulocytes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6095827 |
| Halenda SP and Feinstein MB | Phorbol myristate acetate stimulates formation of phosphatidyl inositol 4-phosphate and phosphatidyl inositol 4,5-bisphosphate in human platelets. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6093804 |
| Enyedi A et al. | Cyclic AMP-dependent protein kinase and Ca2+-calmodulin stimulate the formation of polyphosphoinositides in a sarcoplasmic reticulum preparation of rabbit heart. | 1984 | FEBS Lett. | pmid:6092135 |
| Ishizuka Y et al. | Polyphosphoinositide turnover in rat mast cells stimulated by antigen: rapid and preferential breakdown of phosphatidylinositol 4-phosphate (DPI). | 1984 | Biochem. Biophys. Res. Commun. | pmid:6091652 |
| de Chaffoy de Courcelles D et al. | 1-Oleoyl-2-acetyl-glycerol (OAG) stimulates the formation of phosphatidylinositol 4-phosphate in intact human platelets. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6091634 |
| Kolesnick RN and Gershengorn MC | Ca2+ ionophores affect phosphoinositide metabolism differently than thyrotropin-releasing hormone in GH3 pituitary cells. | 1984 | J. Biol. Chem. | pmid:6086636 |
| Ahaley SS | Synaptojanin regulates Hedgehog signalling by modulating phosphatidylinositol 4-phosphate levels. | 2018 | J. Biosci. | pmid:30541947 |
| Weber S et al. | -Containing Vacuoles Capture PtdIns(4)-Rich Vesicles Derived from the Golgi Apparatus. | 2018 | MBio | pmid:30538188 |
| Riozzi A et al. | Erythrocyte phosphoinositide metabolism in essential hypertensive patients and their normotensive offspring. | 1987 | Clin. Sci. | pmid:3038455 |
| English D et al. | Relationship of phosphatidylinositol bisphosphate hydrolysis to calcium mobilization and functional activation in fluoride-treated neutrophils. | 1987 | J. Clin. Invest. | pmid:3036911 |
| Verhoeven AJ et al. | Turnover of the phosphomonoester groups of polyphosphoinositol lipids in unstimulated human platelets. | 1987 | Eur. J. Biochem. | pmid:3036523 |
| Whipps DE et al. | Effects of glucagon and Ca2+ on the metabolism of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in isolated rat hepatocytes and plasma membranes. | 1987 | Biochem. J. | pmid:3036077 |
| Verhoeven AJ et al. | Stimulation of phosphate uptake in human platelets by thrombin and collagen. Changes in specific 32P labeling of metabolic ATP and polyphosphoinositides. | 1987 | J. Biol. Chem. | pmid:3034877 |
| Enyedi A et al. | The maximal velocity and the calcium affinity of the red cell calcium pump may be regulated independently. | 1987 | J. Biol. Chem. | pmid:3032968 |
| O'Brian CA et al. | The activation of protein kinase C by the polyphosphoinositides phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-monophosphate. | 1987 | FEBS Lett. | pmid:3032687 |
| Bonvini E et al. | Interleukin 2 rapidly stimulates synthesis and breakdown of polyphosphoinositides in interleukin 2-dependent, murine T-cell lines. | 1987 | J. Biol. Chem. | pmid:3031064 |
| Stokes CE and Hawthorne JN | Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains. | 1987 | J. Neurochem. | pmid:3029323 |
| Imai A et al. | Differential regulation by phosphatidylinositol 4,5-bisphosphate of pituitary plasma-membrane and cytosolic phosphoinositide kinases. | 1986 | Biochem. J. | pmid:3028374 |
| MacDonald ML et al. | Regulation of phosphoinositide phosphorylation in Swiss 3T3 cells stimulated by platelet-derived growth factor. | 1987 | J. Biol. Chem. | pmid:3027078 |
| Palmer S et al. | The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytes. | 1986 | Biochem. J. | pmid:3026353 |
| Vickers JD and Mustard JF | The phosphoinositides exist in multiple metabolic pools in rabbit platelets. | 1986 | Biochem. J. | pmid:3026351 |
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| Tysnes OB et al. | Phosphate turnover of phosphatidylinositol in resting and thrombin-stimulated platelets. | 1986 | Biochim. Biophys. Acta | pmid:3022825 |
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phosphatidylinositol-4-phosphate
phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phosphatidylinositol-4-phosphate?
phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phosphatidylinositol-4-phosphate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phosphatidylinositol-4-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phosphatidylinositol-4-phosphate?
There are no associated biomedical information in the current reference collection.