| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Banerjee S et al. | Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. | 2018 | PLoS Pathog. | pmid:29782554 |
| Ahaley SS | Synaptojanin regulates Hedgehog signalling by modulating phosphatidylinositol 4-phosphate levels. | 2018 | J. Biosci. | pmid:30541947 |
| Weber S et al. | -Containing Vacuoles Capture PtdIns(4)-Rich Vesicles Derived from the Golgi Apparatus. | 2018 | MBio | pmid:30538188 |
| Zhang Q et al. | Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth. | 2018 | Plant Cell Physiol. | pmid:30107538 |
| Moriwaki Y et al. | SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes. | 2018 | PLoS ONE | pmid:29953492 |
| Platre MP et al. | A Combinatorial Lipid Code Shapes the Electrostatic Landscape of Plant Endomembranes. | 2018 | Dev. Cell | pmid:29754803 |
| Del Bel LM et al. | The phosphoinositide phosphatase Sac1 regulates cell shape and microtubule stability in the developing eye. | 2018 | Development | pmid:29752385 |
| Lundquist MR et al. | Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. | 2018 | Mol. Cell | pmid:29727621 |
| Oh HS et al. | Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides. | 2018 | PLoS Pathog. | pmid:29702686 |
| Melia CE et al. | The Origin, Dynamic Morphology, and PI4P-Independent Formation of Encephalomyocarditis Virus Replication Organelles. | 2018 | MBio | pmid:29666283 |
| Iwama R et al. | Osh6p, a homologue of the oxysterol-binding protein, is involved in production of functional cytochrome P450 belonging to CYP52 family in n-alkane-assimilating yeast Yarrowia lipolytica. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29621549 |
| Tomioku KN et al. | Nanoscale domain formation of phosphatidylinositol 4-phosphate in the plasma and vacuolar membranes of living yeast cells. | 2018 | Eur. J. Cell Biol. | pmid:29609807 |
| Madukwe JC et al. | G protein βγ subunits directly interact with and activate phospholipase Cϵ. | 2018 | J. Biol. Chem. | pmid:29535186 |
| Minogue S | The Many Roles of Type II Phosphatidylinositol 4-Kinases in Membrane Trafficking: New Tricks for Old Dogs. | 2018 | Bioessays | pmid:29280156 |
| Du X et al. | The role of oxysterol-binding protein and its related proteins in cancer. | 2018 | Semin. Cell Dev. Biol. | pmid:28733164 |
| Mukherjee P et al. | Lipid and membrane recognition by the oxysterol binding protein and its phosphomimetic mutant using dual polarization interferometry. | 2018 | Biochim Biophys Acta Biomembr | pmid:29879417 |
| He K et al. | Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic. | 2017 | Nature | pmid:29236694 |
| Allgood SC et al. | Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner. | 2017 | Front Cell Infect Microbiol | pmid:28944216 |
| Gulyás G et al. | Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins. | 2017 | J. Biol. Chem. | pmid:28939768 |
| Anitei M et al. | Spatiotemporal Control of Lipid Conversion, Actin-Based Mechanical Forces, and Curvature Sensors during Clathrin/AP-1-Coated Vesicle Biogenesis. | 2017 | Cell Rep | pmid:28854360 |
| Zhang JQ et al. | Persistency of Enlarged Autolysosomes Underscores Nanoparticle-Induced Autophagy in Hepatocytes. | 2017 | Small | pmid:27925395 |
| Khadka B and Gupta RS | Identification of a conserved 8 aa insert in the PIP5K protein in the Saccharomycetaceae family of fungi and the molecular dynamics simulations and structural analysis to investigate its potential functional role. | 2017 | Proteins | pmid:28407364 |
| Acosta-Andrade C et al. | Polyamine-RNA-membrane interactions: From the past to the future in biology. | 2017 | Colloids Surf B Biointerfaces | pmid:28456048 |
| Mesmin B et al. | Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP. | 2017 | EMBO J. | pmid:28978670 |
| Banerjee S and Kane PM | Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast. | 2017 | Mol. Biol. Cell | pmid:28720663 |
| Prashek J et al. | Interaction between the PH and START domains of ceramide transfer protein competes with phosphatidylinositol 4-phosphate binding by the PH domain. | 2017 | J. Biol. Chem. | pmid:28652409 |
| Yoshida A et al. | Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membrane. | 2017 | Biochim Biophys Acta Biomembr | pmid:28648675 |
| Hanes CM et al. | Golgi-Associated Protein Kinase C-ε Is Delivered to Phagocytic Cups: Role of Phosphatidylinositol 4-Phosphate. | 2017 | J. Immunol. | pmid:28539432 |
| Manik MK et al. | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction. | 2017 | Structure | pmid:28319008 |
| Azouaoui H et al. | High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions. | 2017 | J. Biol. Chem. | pmid:28302728 |
| Wu F et al. | Hedgehog Signaling: From Basic Biology to Cancer Therapy. | 2017 | Cell Chem Biol | pmid:28286127 |
| Altan-Bonnet N | Lipid Tales of Viral Replication and Transmission. | 2017 | Trends Cell Biol. | pmid:27838086 |
| Rizzo R et al. | GOLPH3 and oncogenesis: What is the molecular link? | 2017 | Tissue Cell | pmid:27378035 |
| Ghai R et al. | ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P ) and regulate its level at the plasma membrane. | 2017 | Nat Commun | pmid:28970484 |
| Zhao K and Ridgway ND | Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System. | 2017 | Cell Rep | pmid:28564600 |
| Charman M et al. | Oxysterol-binding protein recruitment and activity at the endoplasmic reticulum-Golgi interface are independent of Sac1. | 2017 | Traffic | pmid:28471037 |
| Sayyed SG et al. | The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins. | 2017 | Kidney Int. | pmid:28302370 |
| Li L et al. | A phosphoinositide-specific phospholipase C pathway elicits stress-induced Ca signals and confers salt tolerance to rice. | 2017 | New Phytol. | pmid:28157263 |
| Sampaio LS et al. | Bioactive lipids are altered in the kidney of chronic undernourished rats: is there any correlation with the progression of prevalent nephropathies? | 2017 | Lipids Health Dis | pmid:29246161 |
| Hirama T et al. | Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. | 2017 | J. Biol. Chem. | pmid:28698382 |
| De Craene JO et al. | Phosphoinositides, Major Actors in Membrane Trafficking and Lipid Signaling Pathways. | 2017 | Int J Mol Sci | pmid:28294977 |
| Bone LN et al. | The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic. | 2017 | Mol. Biol. Cell | pmid:28035047 |
| Levin R et al. | Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis. | 2017 | Mol. Biol. Cell | pmid:28035045 |
| Marquer C et al. | Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. | 2016 | Nat Commun | pmid:27336679 |
| Tabaei SR et al. | Multistep Compositional Remodeling of Supported Lipid Membranes by Interfacially Active Phosphatidylinositol Kinases. | 2016 | Anal. Chem. | pmid:27118725 |
| Anderson KE et al. | Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells. | 2016 | Adv Biol Regul | pmid:26639089 |
| Moser von Filseck J and Drin G | Running up that hill: How to create cellular lipid gradients by lipid counter-flows. | 2016 | Biochimie | pmid:27519300 |
| Mesmin B and Antonny B | The counterflow transport of sterols and PI4P. | 2016 | Biochim. Biophys. Acta | pmid:26928592 |
| Kentala H et al. | OSBP-Related Protein Family: Mediators of Lipid Transport and Signaling at Membrane Contact Sites. | 2016 | Int Rev Cell Mol Biol | pmid:26811291 |
| Ketel K et al. | A phosphoinositide conversion mechanism for exit from endosomes. | 2016 | Nature | pmid:26760201 |
| Kim E et al. | IPMK: A versatile regulator of nuclear signaling events. | 2016 | Adv Biol Regul | pmid:26682649 |
| Domingues L et al. | The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells. | 2016 | Cell. Microbiol. | pmid:26676327 |
| Dong N et al. | Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector. | 2016 | Nat Microbiol | pmid:27941800 |
| Zhang J et al. | Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy. | 2016 | Int. J. Biochem. Cell Biol. | pmid:26589722 |
| Simon ML et al. | A PtdIns(4)P-driven electrostatic field controls cell membrane identity and signalling in plants. | 2016 | Nat Plants | pmid:27322096 |
| Yin P et al. | A role for retromer in hepatitis C virus replication. | 2016 | Cell. Mol. Life Sci. | pmid:26298293 |
| Alli-Balogun GO et al. | Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype. | 2016 | Mol. Biol. Cell | pmid:27798239 |
| Xing M et al. | GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. | 2016 | Mol. Biol. Cell | pmid:27708138 |
| Baumlova A et al. | The structural basis for calcium inhibition of lipid kinase PI4K IIalpha and comparison with the apo state. | 2016 | Physiol Res | pmid:27539108 |
| Jin MW et al. | [Effect of phosphoinositide 4-phosphate on invasion and migration of human glioma U87 cells]. | 2016 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:27530799 |
| Dong R et al. | Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P. | 2016 | Cell | pmid:27419871 |
| Ijuin T et al. | Regulation of CD44 expression and focal adhesion by Golgi phosphatidylinositol 4-phosphate in breast cancer. | 2016 | Cancer Sci. | pmid:27178239 |
| Tenorio MJ et al. | Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2016 | PLoS ONE | pmid:27123979 |
| Berryman S et al. | Foot-and-mouth disease virus replicates independently of phosphatidylinositol 4-phosphate and type III phosphatidylinositol 4-kinases. | 2016 | J. Gen. Virol. | pmid:27093462 |
| Lopes da Silva M et al. | Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells. | 2016 | J. Cell. Sci. | pmid:27068535 |
| Dickson EJ et al. | Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides. | 2016 | J. Cell Biol. | pmid:27044890 |
| Sohn M et al. | Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27044099 |
| Klima M et al. | Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein. | 2016 | Sci Rep | pmid:27009356 |
| Yoshida A et al. | Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane. | 2016 | Biochim. Biophys. Acta | pmid:26972044 |
| Jiang K et al. | PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail. | 2016 | PLoS Biol. | pmid:26863604 |
| Henmi Y et al. | PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes. | 2016 | Mol. Biol. Cell | pmid:26823017 |
| Stalder D and Novick PJ | The casein kinases Yck1p and Yck2p act in the secretory pathway, in part, by regulating the Rab exchange factor Sec2p. | 2016 | Mol. Biol. Cell | pmid:26700316 |
| Tóth JT et al. | BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation. | 2016 | Biochim. Biophys. Acta | pmid:26692031 |
| Goto A et al. | Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools. | 2016 | J. Biol. Chem. | pmid:26601944 |
| Baskin JM et al. | The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. | 2016 | Nat. Cell Biol. | pmid:26571211 |
| Tsutsui Y et al. | Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src. | 2015 | Biochemistry | pmid:25961473 |
| Stalder D and Novick PJ | Assaying the interaction of the Rab guanine nucleotide exchange protein Sec2 with the upstream Rab, a downstream effector, and a phosphoinositide. | 2015 | Methods Mol. Biol. | pmid:25800834 |
| Nchoutmboube J et al. | Enterovirus replication: go with the (counter)flow. | 2015 | Trends Microbiol. | pmid:25748799 |
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| Hu J et al. | Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled. | 2015 | Nat Commun | pmid:26365782 |
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phosphatidylinositol-4-phosphate
phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phosphatidylinositol-4-phosphate?
phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phosphatidylinositol-4-phosphate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phosphatidylinositol-4-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phosphatidylinositol-4-phosphate?
There are no associated biomedical information in the current reference collection.