phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Fairn GD et al. The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17881569
Wang J et al. PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. 2007 Mol. Biol. Cell pmid:17494868
Jeganathan S and Lee JM Binding of elongation factor eEF1A2 to phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation. 2007 J. Biol. Chem. pmid:17088255
D'Angelo G et al. Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. 2007 Nature pmid:17687330
Posada V et al. Maximal Ca2+i stimulation of cardiac Na+/Ca2+ exchange requires simultaneous alkalinization and binding of PtdIns-4,5-P2 to the exchanger. 2007 Biol. Chem. pmid:17338635
König S et al. Stress-inducible and constitutive phosphoinositide pools have distinctive fatty acid patterns in Arabidopsis thaliana. 2007 FASEB J. pmid:17327357
Beck Z et al. Calcium modulation of monoclonal antibody binding to phosphatidylinositol phosphate. 2007 Biochem. Biophys. Res. Commun. pmid:17257584
Jarquin-Pardo M et al. Phosphatidic acid regulates the affinity of the murine phosphatidylinositol 4-phosphate 5-kinase-Ibeta for phosphatidylinositol-4-phosphate. 2007 J. Cell. Biochem. pmid:16888807
Blumental-Perry A et al. Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER export. 2006 Dev. Cell pmid:17084359
Jeynov B et al. Phosphoinositide synthesis and degradation in isolated rat liver peroxisomes. 2006 FEBS Lett. pmid:17045591
Shiozawa K et al. The common phospholipid-binding activity of the N-terminal domains of PEX1 and VCP/p97. 2006 FEBS J. pmid:17018057
Cameroni E et al. Phosphatidylinositol 4-phosphate is required for translation initiation in Saccharomyces cerevisiae. 2006 J. Biol. Chem. pmid:17005563
Yamashita S et al. PI4P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy. 2006 J. Cell Biol. pmid:16754956
Weber SS et al. Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole. 2006 PLoS Pathog. pmid:16710455
Baust T et al. Proteomic analysis of adaptor protein 1A coats selectively assembled on liposomes. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16492770
Hilbi H Modulation of phosphoinositide metabolism by pathogenic bacteria. 2006 Cell. Microbiol. pmid:16939534
Balla A and Balla T Phosphatidylinositol 4-kinases: old enzymes with emerging functions. 2006 Trends Cell Biol. pmid:16793271
Andersen JF and Ribeiro JM A secreted salivary inositol polyphosphate 5-phosphatase from a blood-feeding insect: allosteric activation by soluble phosphoinositides and phosphatidylserine. 2006 Biochemistry pmid:16634626
Olas B et al. Resveratrol inhibits polyphosphoinositide metabolism in activated platelets. 2005 Biochim. Biophys. Acta pmid:16051184
Waselle L et al. Role of phosphoinositide signaling in the control of insulin exocytosis. 2005 Mol. Endocrinol. pmid:16081518