phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Monks DE et al. Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol transfer protein homolog through activation of the protein kinases SPK1 and SPK2. 2001 Plant Cell pmid:11340192
Simonsen A et al. The role of phosphoinositides in membrane transport. 2001 Curr. Opin. Cell Biol. pmid:11454456
Foti M et al. Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. 2001 Mol. Biol. Cell pmid:11514624
Zhao X et al. Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and affects membrane trafficking in COS-7 cells. 2001 J. Biol. Chem. pmid:11526106
Ago T et al. The PX domain as a novel phosphoinositide- binding module. 2001 Biochem. Biophys. Res. Commun. pmid:11563857
Kim YW et al. Arabidopsis dynamin-like 2 that binds specifically to phosphatidylinositol 4-phosphate assembles into a high-molecular weight complex in vivo and in vitro. 2001 Plant Physiol. pmid:11706203
Meijer HJ et al. Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monophosphate (PtdIns5P), and its accumulation upon osmotic stress. 2001 Biochem. J. pmid:11716778
Konrad G et al. Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport. 2002 J. Biol. Chem. pmid:11792713
Ishiyama N et al. The effects of deimination of myelin basic protein on structures formed by its interaction with phosphoinositide-containing lipid monolayers. 2001 J. Struct. Biol. pmid:11858705
Audhya A and Emr SD Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. 2002 Dev. Cell pmid:12015967
Nasuhoglu C et al. Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions. 2002 Am. J. Physiol., Cell Physiol. pmid:12055091
Jung JY et al. Phosphatidylinositol 3- and 4-phosphate are required for normal stomatal movements. 2002 Plant Cell pmid:12368494
De Matteis M et al. Phosphoinositides and the golgi complex. 2002 Curr. Opin. Cell Biol. pmid:12383794
Wu B et al. Phosphatidylinositol and PI-4-monophosphate recover amyloid beta protein-induced inhibition of Cl- -ATPase activity. 2002 Life Sci. pmid:12467886
Rajebhosale M et al. Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells. 2003 J. Biol. Chem. pmid:12471042
Hill CM et al. Terminal deletion mutants of myelin basic protein: new insights into self-association and phospholipid interactions. 2003 Micron pmid:12694855
Wang YJ et al. Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. 2003 Cell pmid:12914695
Waugh MG et al. Identification and characterization of differentially active pools of type IIalpha phosphatidylinositol 4-kinase activity in unstimulated A431 cells. 2003 Biochem. J. pmid:12954081
Roldan ER and Harrison RA The role of diacylglycerol in the exocytosis of the sperm acrosome. Studies using diacylglycerol lipase and diacylglycerol kinase inhibitors and exogenous diacylglycerols. 1992 Biochem. J. pmid:1311174
Khalaf LJ and Laychock SG Phosphatidylinositol availability and polyphosphoinositide synthesis in pancreatic islet cell membranes. 1992 Biochem. Pharmacol. pmid:1314058