| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gagne JM and Clark SE | The Arabidopsis stem cell factor POLTERGEIST is membrane localized and phospholipid stimulated. | 2010 | Plant Cell | pmid:20348433 |
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| Wuttke A et al. | Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P2 dynamics in secretagogue-stimulated beta-cells. | 2010 | J. Cell. Sci. | pmid:20375060 |
| Carvou N et al. | Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum. | 2010 | J. Cell. Sci. | pmid:20332109 |
| Lenoir M et al. | Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains. | 2010 | EMBO Rep. | pmid:20300118 |
| Moorhead AM et al. | Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion. | 2010 | Infect. Immun. | pmid:20231409 |
| Minogue S et al. | Relationship between phosphatidylinositol 4-phosphate synthesis, membrane organization, and lateral diffusion of PI4KIIalpha at the trans-Golgi network. | 2010 | J. Lipid Res. | pmid:20388919 |
| Levine TP | Lipid traffic: Osh4p makes an unexpected exchange. | 2011 | J. Cell Biol. | pmid:22162132 |
| Tai AW and Salloum S | The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement. | 2011 | PLoS ONE | pmid:22022594 |
| MartÃn-Acebes MA et al. | West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipids. | 2011 | PLoS ONE | pmid:21949814 |
| Zakharian E et al. | Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5) Pâ‚‚. | 2011 | FASEB J. | pmid:21810903 |
| Santiago-Tirado FH and Bretscher A | Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network. | 2011 | Trends Cell Biol. | pmid:21764313 |
| Berger KL et al. | Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication. | 2011 | J. Virol. | pmid:21697487 |
| He J et al. | Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. | 2011 | J. Biol. Chem. | pmid:21454700 |
| Malhotra V and Campelo F | PKD regulates membrane fission to generate TGN to cell surface transport carriers. | 2011 | Cold Spring Harb Perspect Biol | pmid:21421913 |
| Shen B et al. | Protein targeting to exosomes/microvesicles by plasma membrane anchors. | 2011 | J. Biol. Chem. | pmid:21300796 |
| Reiss S et al. | Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. | 2011 | Cell Host Microbe | pmid:21238945 |
| Santiago-Tirado FH et al. | PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast. | 2011 | Dev. Cell | pmid:21238924 |
| Lorente-RodrÃguez A and Barlowe C | Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments. | 2011 | Mol. Biol. Cell | pmid:21119004 |
| Waugh MG et al. | Detergent-free isolation and characterization of cholesterol-rich membrane domains from trans-Golgi network vesicles. | 2011 | J. Lipid Res. | pmid:21191144 |
| Matyas GR and Alving CR | Antigen-specific enhancement of natural human IgG antibodies to phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol-4-phosphate, cholesterol, and lipid A by a liposomal vaccine containing lipid A. | 2011 | Vaccine | pmid:21624414 |
| de Saint-Jean M et al. | Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. | 2011 | J. Cell Biol. | pmid:22162133 |
| Lenoir M et al. | Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1. | 2011 | Biomol NMR Assign | pmid:21298564 |
| He J et al. | Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications. | 2011 | Chem. Biol. | pmid:22035800 |
| Nakatsu F et al. | PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity. | 2012 | J. Cell Biol. | pmid:23229899 |
| Bishé B et al. | Phosphoinositides in the hepatitis C virus life cycle. | 2012 | Viruses | pmid:23202467 |
| van der Schaar HM et al. | Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication. | 2012 | Cell Res. | pmid:22945356 |
| Shulga YV et al. | Phosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activator. | 2012 | J. Biol. Chem. | pmid:22942276 |
| Tu L et al. | A conserved N-terminal arginine-motif in GOLPH3-family proteins mediates binding to coatomer. | 2012 | Traffic | pmid:22889169 |
| Piao H et al. | Metabolic activation of the HOG MAP kinase pathway by Snf1/AMPK regulates lipid signaling at the Golgi. | 2012 | Traffic | pmid:22882253 |
| Baird NL et al. | Arenavirus infection induces discrete cytosolic structures for RNA replication. | 2012 | J. Virol. | pmid:22875974 |
| Bishé B et al. | Role of phosphatidylinositol 4-phosphate (PI4P) and its binding protein GOLPH3 in hepatitis C virus secretion. | 2012 | J. Biol. Chem. | pmid:22745132 |
| Hammond GR et al. | PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. | 2012 | Science | pmid:22722250 |
| Jobe O et al. | An anti-phosphoinositide-specific monoclonal antibody that neutralizes HIV-1 infection of human monocyte-derived macrophages. | 2012 | Virology | pmid:22633000 |
| Wood CS et al. | Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase. | 2012 | Mol. Biol. Cell | pmid:22553352 |
| Boggs JM et al. | Effect of phosphorylation of phosphatidylinositol on myelin basic protein-mediated binding of actin filaments to lipid bilayers in vitro. | 2012 | Biochim. Biophys. Acta | pmid:22538354 |
| Lefèbvre F et al. | Secretory pathway-dependent localization of the Saccharomyces cerevisiae Rho GTPase-activating protein Rgd1p at growth sites. | 2012 | Eukaryotic Cell | pmid:22447923 |
| Bianco A et al. | Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity. | 2012 | PLoS Pathog. | pmid:22412376 |
| Mousley CJ et al. | Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate Golgi functionality. | 2012 | Subcell. Biochem. | pmid:22374094 |
| Zhang L et al. | ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication. | 2012 | PLoS ONE | pmid:22359663 |
| Jacquot A et al. | Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate. | 2012 | J. Biol. Chem. | pmid:22351780 |
| Han WQ et al. | Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells. | 2012 | J. Cell. Sci. | pmid:22349696 |
| Daboussi L et al. | Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network. | 2012 | Nat. Cell Biol. | pmid:22344030 |
| Saxena V et al. | Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft. | 2012 | J. Virol. | pmid:22301157 |
| Delang L et al. | The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication. | 2012 | Biochem. Pharmacol. | pmid:22885339 |
| Fairn GD and Grinstein S | Cell biology. Precursor or charge supplier? | 2012 | Science | pmid:22879491 |
| Waugh MG | Phosphatidylinositol 4-kinases, phosphatidylinositol 4-phosphate and cancer. | 2012 | Cancer Lett. | pmid:22750097 |
| Minogue S and Waugh MG | The phosphatidylinositol 4-kinases: don't call it a comeback. | 2012 | Subcell. Biochem. | pmid:22403072 |
| D'Angelo G et al. | Phosphoinositides in Golgi complex function. | 2012 | Subcell. Biochem. | pmid:22374093 |
| Sun Y and Drubin DG | Pik1-ing clathrin adaptors. | 2012 | Nat. Cell Biol. | pmid:22344031 |
| Gonorazky G et al. | Phosphatidylinositol 4-phosphate is associated to extracellular lipoproteic fractions and is detected in tomato apoplastic fluids. | 2012 | Plant Biol (Stuttg) | pmid:21972816 |
| McNamara CW et al. | Targeting Plasmodium PI(4)K to eliminate malaria. | 2013 | Nature | pmid:24284631 |
| Stalder D et al. | Phosphorylation of the Rab exchange factor Sec2p directs a switch in regulatory binding partners. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24248333 |
| Mesmin B et al. | A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP. | 2013 | Cell | pmid:24209621 |
| Wieffer M et al. | PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling. | 2013 | Curr. Biol. | pmid:24206846 |
| Lukacs V et al. | Promiscuous activation of transient receptor potential vanilloid 1 (TRPV1) channels by negatively charged intracellular lipids: the key role of endogenous phosphoinositides in maintaining channel activity. | 2013 | J. Biol. Chem. | pmid:24158445 |
| Zhou X et al. | Auto-inhibition of Drs2p, a yeast phospholipid flippase, by its carboxyl-terminal tail. | 2013 | J. Biol. Chem. | pmid:24045945 |
| Tavoosi N et al. | Factor VII and protein C are phosphatidic acid-binding proteins. | 2013 | Biochemistry | pmid:23879866 |
| Levine TP and Menon AK | A protein pair with PIPs inside. | 2013 | Structure | pmid:23823324 |
| Tong J et al. | Structure of Osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins. | 2013 | Structure | pmid:23791945 |
| Clayton EL et al. | Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks. | 2013 | Prog. Lipid Res. | pmid:23608234 |
| Zhang L et al. | Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy. | 2013 | Cell | pmid:23540699 |
| Forrest S et al. | Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis. | 2013 | Hum. Mol. Genet. | pmid:23492670 |
| Ng MM et al. | GOLPH3L antagonizes GOLPH3 to determine Golgi morphology. | 2013 | Mol. Biol. Cell | pmid:23345592 |
| Munnik T | Analysis of D3-,4-,5-phosphorylated phosphoinositides using HPLC. | 2013 | Methods Mol. Biol. | pmid:23681519 |
| D'Angelo G et al. | Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. | 2013 | Nature | pmid:23913272 |
| Lenoir M and Overduin M | PtdIns(4)P signalling and recognition systems. | 2013 | Adv. Exp. Med. Biol. | pmid:23775691 |
| De Matteis MA et al. | Phosphatidylinositol-4-phosphate: the Golgi and beyond. | 2013 | Bioessays | pmid:23712958 |
| Bayot A et al. | Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies. | 2013 | Hum. Mol. Genet. | pmid:23552101 |
| Niu Y et al. | PtdIns(4)P regulates retromer-motor interaction to facilitate dynein-cargo dissociation at the trans-Golgi network. | 2013 | Nat. Cell Biol. | pmid:23524952 |
| Park J et al. | Deleterious effects of soluble amyloid-β oligomers on multiple steps of synaptic vesicle trafficking. | 2013 | Neurobiol. Dis. | pmid:23523634 |
| Clayton EL et al. | Phosphatidylinositol 4-kinases and PI4P metabolism in the nervous system: roles in psychiatric and neurological diseases. | 2013 | Mol. Neurobiol. | pmid:23054682 |
| Delage E et al. | Signal transduction pathways involving phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: convergences and divergences among eukaryotic kingdoms. | 2013 | Prog. Lipid Res. | pmid:22981911 |
| Tokuda E et al. | Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion and invasive cell migration in human breast cancer. | 2014 | Cancer Res. | pmid:24706697 |
| Ishikawa-Sasaki K et al. | A complex comprising phosphatidylinositol 4-kinase IIIβ, ACBD3, and Aichi virus proteins enhances phosphatidylinositol 4-phosphate synthesis and is critical for formation of the viral replication complex. | 2014 | J. Virol. | pmid:24672044 |
| Li H et al. | Hepatitis C virus NS5A hijacks ARFGAP1 to maintain a phosphatidylinositol 4-phosphate-enriched microenvironment. | 2014 | J. Virol. | pmid:24623438 |
| Del Campo CM et al. | Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM. | 2014 | Structure | pmid:24530282 |
| Klinkenberg D et al. | A cascade of ER exit site assembly that is regulated by p125A and lipid signals. | 2014 | J. Cell. Sci. | pmid:24522181 |
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| Bojjireddy N et al. | Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. | 2014 | J. Biol. Chem. | pmid:24415756 |
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phosphatidylinositol-4-phosphate
phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phosphatidylinositol-4-phosphate?
phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phosphatidylinositol-4-phosphate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phosphatidylinositol-4-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phosphatidylinositol-4-phosphate?
There are no associated biomedical information in the current reference collection.