| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Suer S et al. | Human phosphatidylinositol 4-kinase isoform PI4K92. Expression of the recombinant enzyme and determination of multiple phosphorylation sites. | 2001 | Eur. J. Biochem. | pmid:11277933 |
| Carricaburu V and Fournier B | Phosphoinositide fatty acids regulate phosphatidylinositol 5-kinase, phospholipase C and protein kinase C activities. | 2001 | Eur. J. Biochem. | pmid:11231275 |
| Hsu FF and Turk J | Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study. | 2000 | J. Am. Soc. Mass Spectrom. | pmid:11073262 |
| Arcaro A et al. | Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors. | 2000 | Mol. Cell. Biol. | pmid:10805725 |
| Frohman MA et al. | Regulation of phospholipase D1 activity by Rho GTPases. | 2000 | Meth. Enzymol. | pmid:11036603 |
| Tharmapathy P et al. | The stimulatory effects of cationic amphiphilic drugs on human platelets treated with thrombin. | 2000 | Biochem. Pharmacol. | pmid:11008120 |
| Baukrowitz T and Fakler B | K(ATP) channels: linker between phospholipid metabolism and excitability. | 2000 | Biochem. Pharmacol. | pmid:10930527 |
| Gonzalez-Agosti C et al. | Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF. | 1999 | J. Biol. Chem. | pmid:10567424 |
| Hama H et al. | Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. | 1999 | J. Biol. Chem. | pmid:10567405 |
| Sorensen SD et al. | Inhibition of beta(2)-adrenergic and muscarinic cholinergic receptor endocytosis after depletion of phosphatidylinositol bisphosphate. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10411568 |
| Rivas MP et al. | Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. | 1999 | Mol. Biol. Cell | pmid:10397762 |
| Kim D and Bang H | Modulation of rat atrial G protein-coupled K+ channel function by phospholipids. | 1999 | J. Physiol. (Lond.) | pmid:10226149 |
| Stock SD et al. | SEC14-dependent secretion in Saccharomyces cerevisiae. Nondependence on sphingolipid synthesis-coupled diacylglycerol production. | 1999 | J. Biol. Chem. | pmid:10224046 |
| Basu SS et al. | A phosphotransferase that generates phosphatidylinositol 4-phosphate (PtdIns-4-P) from phosphatidylinositol and lipid A in Rhizobium leguminosarum. A membrane-bound enzyme linking lipid a and ptdins-4-p biosynthesis. | 1999 | J. Biol. Chem. | pmid:10196199 |
| Zhainazarov AB and Ache BW | Effects of phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate on a Na+-gated nonselective cation channel. | 1999 | J. Neurosci. | pmid:10191310 |
| Nagano K et al. | A novel phospholipase C delta4 (PLCdelta4) splice variant as a negative regulator of PLC. | 1999 | J. Biol. Chem. | pmid:9915823 |
| RÃpová D et al. | Phosphoinositide signalling system in platelets of schizophrenic patients and the effect of neuroleptic therapy. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10509868 |
| Neri LM et al. | Monocytic differentiation of HL-60 cells is characterized by the nuclear translocation of phosphatidylinositol 3-kinase and of definite phosphatidylinositol-specific phospholipase C isoforms. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10362505 |
| Cooke FT et al. | The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. | 1998 | Curr. Biol. | pmid:9811604 |
| Hinchliffe KA et al. | PIPkins1, their substrates and their products: new functions for old enzymes. | 1998 | Biochim. Biophys. Acta | pmid:9838059 |
| Baukrowitz T et al. | PIP2 and PIP as determinants for ATP inhibition of KATP channels. | 1998 | Science | pmid:9804555 |
| Shyng SL and Nichols CG | Membrane phospholipid control of nucleotide sensitivity of KATP channels. | 1998 | Science | pmid:9804554 |
| Wang PY et al. | Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide. | 1998 | J. Biol. Chem. | pmid:9733716 |
| Stevenson JM et al. | A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. | 1998 | J. Biol. Chem. | pmid:9712908 |
| Waugh MG et al. | Phosphatidylinositol 4-phosphate synthesis in immunoisolated caveolae-like vesicles and low buoyant density non-caveolar membranes. | 1998 | J. Biol. Chem. | pmid:9642278 |
| Willars GB et al. | Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells. | 1998 | J. Biol. Chem. | pmid:9478953 |
| Linseman DA et al. | Cytoskeletal and phosphoinositide requirements for muscarinic receptor signaling to focal adhesion kinase and paxillin. | 1998 | J. Neurochem. | pmid:9489713 |
| Ryningen A et al. | Elevation of cyclic AMP decreases phosphoinositide turnover and inhibits thrombin-induced secretion in human platelets. | 1998 | Biochim. Biophys. Acta | pmid:9795233 |
| Guilherme A et al. | A novel phosphorylated lipid counteracts activation of the renal plasma membrane (Ca2+ + Mg2+)ATPase by endogenous phosphatidylinositol-4-phosphate. | 1998 | Biosci. Rep. | pmid:9743476 |
| Lukowski S et al. | Fodrin inhibits phospholipases A2, C, and D by decreasing polyphosphoinositide cell content. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9675127 |
| Hollenback D and Glomset JA | On the relation between a stearoyl-specific transacylase from bovine testis membranes and a copurifying acyltransferase. | 1998 | Biochemistry | pmid:9425058 |
| Cheng CH | In vitro and in vivo inhibitory actions of morin on rat brain phosphatidylinositolphosphate kinase activity. | 1997 | Life Sci. | pmid:9366511 |
| Sun SH et al. | Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells. | 1997 | Lipids | pmid:9076664 |
| Rameh LE et al. | A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. | 1997 | Nature | pmid:9367159 |
| Müller E et al. | Dependence on intracellular Ca2+ on mass and turnover of phosphoinositides and phosphatidate in human erythrocytes. | 1997 | Biol. Chem. | pmid:9348118 |
| Mani I et al. | Increased formation of phosphatidylinositol-4-phosphate in human platelets stimulated with lysophosphatidic acid. | 1996 | Lipids | pmid:8972459 |
| Filtz TM et al. | Purification and G protein subunit regulation of a phospholipase C-beta from Xenopus laevis oocytes. | 1996 | J. Biol. Chem. | pmid:8940109 |
| Isenberg G et al. | Probing phosphatidylinositolphosphates and adenosinenucleotides on talin nucleated actin polymerization. | 1996 | FEBS Lett. | pmid:8955371 |
| Salim K et al. | Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. | 1996 | EMBO J. | pmid:8947047 |
| DebBurman SK et al. | G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. | 1996 | J. Biol. Chem. | pmid:8798423 |
| Molz L et al. | Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain. | 1996 | J. Biol. Chem. | pmid:8662856 |
| Tong W and Sun GY | Effects of ethanol on phosphorylation of lipids in rat synaptic plasma membranes. | 1996 | Alcohol. Clin. Exp. Res. | pmid:8947307 |
| Santavenere E et al. | Sensitivity of Daudi cells to tumor necrosis factor alpha: early changes in polyphosphoinositide metabolism. | 1996 | Cell Biol. Int. | pmid:8948126 |
| Ivanenkov VV et al. | Interaction of S100a0 protein with the actin capping protein, CapZ: characterization of a putative S100a0 binding site in CapZ alpha-subunit. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8660341 |
| Loijens JC et al. | The phosphatidylinositol 4-phosphate 5-kinase family. | 1996 | Adv. Enzyme Regul. | pmid:8869744 |
| Apgar JR | Activation of protein kinase C in rat basophilic leukemia cells stimulates increased production of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: correlation with actin polymerization. | 1995 | Mol. Biol. Cell | pmid:7749199 |
| Starling AP et al. | Phosphatidylinositol 4-phosphate increases the rate of dephosphorylation of the phosphorylated Ca(2+)-ATPase. | 1995 | J. Biol. Chem. | pmid:7782308 |
| Ding KH and Liang NC | Inhibition of 5'-chloro-5'-deoxyadenosine on phosphoinositide and protein phosphorylation in swine platelets. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7660821 |
| Stack JH et al. | Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. | 1995 | J. Cell Biol. | pmid:7721937 |
| Martelli AM et al. | Inositides in nuclei of Friend cells: changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation. | 1995 | Cell. Signal. | pmid:7756111 |
| Vickers JD | Extraction of polyphosphoinositides from platelets: comparison of a two-step procedure with a common single-step extraction procedure. | 1995 | Anal. Biochem. | pmid:7710110 |
| Roldan ER et al. | Exocytosis in spermatozoa in response to progesterone and zona pellucida. | 1994 | Science | pmid:7985030 |
| Tong W and Sun GY | Phosphorylation of lipids in rat primary glial cells and immortalized astrocytes (DITNC). | 1994 | Lipids | pmid:8090058 |
| James SR et al. | Interfacial hydrolysis of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate by turkey erythrocyte phospholipase C. | 1994 | Biochem. J. | pmid:8135761 |
| Pacini L et al. | Effects of perphenazine on the metabolism of inositol phospholipids in SK-N-BE(2) human neuroblastoma cells. | 1994 | Biochem. Pharmacol. | pmid:7980631 |
| Girton RA et al. | 15-HETE: selective incorporation into inositol phospholipids of MDCK cells. | 1994 | Kidney Int. | pmid:8007600 |
| Björk J and Backman L | Sodium selenite as modulator of red cell shape. | 1994 | Biochim. Biophys. Acta | pmid:8155668 |
| Zeng XT et al. | Electrogenic and phosphatidylinositol-4-monophosphate-stimulated Cl- transport by Cl- pump in the rat brain. | 1994 | Brain Res. | pmid:8019845 |
| Ohnuma M and Mabuchi I | 45K actin filament-severing protein from sea urchin eggs: interaction with phosphatidylinositol-4,5-bisphosphate. | 1993 | J. Biochem. | pmid:8113226 |
| Brearley CA and Hanke DE | Pathway of synthesis of 3,4- and 4,5-phosphorylated phosphatidylinositols in the duckweed Spirodela polyrhiza L. | 1993 | Biochem. J. | pmid:8382475 |
| Miyazawa A et al. | Immunohistochemical analysis of signal transduction system in developing rat Purkinje cell by using antibodies for signaling molecules. | 1993 | Ann. N. Y. Acad. Sci. | pmid:9137614 |
| Flanagan CA et al. | Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. | 1993 | Science | pmid:8248783 |
| Kurosawa M et al. | Formation of phosphatidylinositol-4-phosphate in human peripheral blood eosinophils. | 1993 | Clin. Exp. Allergy | pmid:10779308 |
| Tran D et al. | Cellular distribution of polyphosphoinositides in rat hepatocytes. | 1993 | Cell. Signal. | pmid:8312134 |
| Santi P et al. | Changes in polyphosphoinositide levels in rat liver nuclei in response to prolactin, a known hepatic mitogen. | 1992 | Cell. Signal. | pmid:1329898 |
| Divecha N et al. | Purification and characterization of phosphatidylinositol 4-phosphate 5-kinases. | 1992 | Biochem. J. | pmid:1334412 |
| Janmey PA et al. | Phosphoinositide-binding peptides derived from the sequences of gelsolin and villin. | 1992 | J. Biol. Chem. | pmid:1318302 |
| Roldan ER and Harrison RA | The role of diacylglycerol in the exocytosis of the sperm acrosome. Studies using diacylglycerol lipase and diacylglycerol kinase inhibitors and exogenous diacylglycerols. | 1992 | Biochem. J. | pmid:1311174 |
| Bordin L et al. | Tyrosine-protein kinase inhibition in human erythrocytes by polyphosphoinositides (PIP and PIP2). | 1992 | Biochem. Biophys. Res. Commun. | pmid:1382423 |
| Fukami K et al. | Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function. | 1992 | Nature | pmid:1326084 |
| Katakami Y et al. | Isolation of the phosphatidylinositol 4-monophosphate dissociable high-affinity profilin-actin complex. | 1992 | Biochim. Biophys. Acta | pmid:1322701 |
| Furuhashi K et al. | Inositol phospholipid-induced suppression of F-actin-gelating activity of smooth muscle filamin. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1317169 |
| Khalaf LJ and Laychock SG | Phosphatidylinositol availability and polyphosphoinositide synthesis in pancreatic islet cell membranes. | 1992 | Biochem. Pharmacol. | pmid:1314058 |
| Walsh JP et al. | Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1656463 |
| Martelli AM et al. | Mitogen-stimulated events in nuclei of Swiss 3T3 cells. Evidence for a direct link between changes of inositol lipids, protein kinase C requirement and the onset of DNA synthesis. | 1991 | FEBS Lett. | pmid:1646120 |
| Lee CH and Hajra AK | Molecular species of diacylglycerols and phosphoglycerides and the postmortem changes in the molecular species of diacylglycerols in rat brains. | 1991 | J. Neurochem. | pmid:1846396 |
| Chauhan A et al. | Interaction of protein kinase C with phosphoinositides. | 1991 | Arch. Biochem. Biophys. | pmid:1654811 |
| de Wolf FA et al. | Characterization of the interaction of doxorubicin with (poly)phosphoinositides in model systems. Evidence for specific interaction with phosphatidylinositol-monophosphate and -diphosphate. | 1991 | FEBS Lett. | pmid:1652476 |
| Kellerer M et al. | Stimulation of phospholipase C activity by insulin is mediated by both isotypes of the human insulin receptor. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1661583 |
| Gascard P et al. | Asymmetric distribution of phosphoinositides and phosphatidic acid in the human erythrocyte membrane. | 1991 | Biochim. Biophys. Acta | pmid:1657164 |
| Conway BR et al. | Comparative effects of epidermal growth factor and carbachol on phosphoinositide synthesis and breakdown in pancreatic acinar cells. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1650199 |
| Tusupov OK et al. | Proteolytic fragment of protein kinase C (kinase M) phosphorylates in vitro phosphatidylinositol-4-phosphate. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1645534 |
| von Euler G and von Euler A | Dopamine D2 receptors attenuate phosphatidylinositol 4,5-bisphosphate in synaptosomal membranes from rat neostriatum. | 1991 | J. Neurochem. | pmid:1846171 |
| Ferchmin PA | Are polyamines modulators of the CNS? | 1991 | Ann. N. Y. Acad. Sci. | pmid:1679312 |
| Cowen DS et al. | P2-purinergic receptors activate a guanine nucleotide-dependent phospholipase C in membranes from HL-60 cells. | 1990 | Biochim. Biophys. Acta | pmid:2166587 |
| Morris SJ et al. | Phosphoinositide metabolism in cultured glioma and neuroblastoma cells: subcellular distribution of enzymes indicate incomplete turnover at the plasma membrane. | 1990 | Biochim. Biophys. Acta | pmid:2156558 |
| Kellerer M et al. | TPA inhibits insulin stimulated PIP hydrolysis in fat cell membranes: evidence for modulation of insulin dependent phospholipase C by proteinkinase C. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2173567 |
| Vickers JD et al. | Inositol phospholipid metabolism in human platelets stimulated by ADP. | 1990 | Eur. J. Biochem. | pmid:2171937 |
| Eng SP and Lo CS | Mastoparan increases membrane bound phosphatidylinositol kinase and phosphatidylinositol 4-monophosphate kinase activities in Madin-Darby canine kidney cells. | 1990 | Life Sci. | pmid:2154653 |
| Machesky LM et al. | The affinities of human platelet and Acanthamoeba profilin isoforms for polyphosphoinositides account for their relative abilities to inhibit phospholipase C. | 1990 | Cell Regul. | pmid:1966040 |
| Bazenet CE et al. | The human erythrocyte contains two forms of phosphatidylinositol-4-phosphate 5-kinase which are differentially active toward membranes. | 1990 | J. Biol. Chem. | pmid:2170402 |
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phosphatidylinositol-4-phosphate
phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phosphatidylinositol-4-phosphate?
phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phosphatidylinositol-4-phosphate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phosphatidylinositol-4-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phosphatidylinositol-4-phosphate?
There are no associated biomedical information in the current reference collection.