phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Marquer C et al. Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. 2016 Nat Commun pmid:27336679
Tabaei SR et al. Multistep Compositional Remodeling of Supported Lipid Membranes by Interfacially Active Phosphatidylinositol Kinases. 2016 Anal. Chem. pmid:27118725
Anderson KE et al. Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells. 2016 Adv Biol Regul pmid:26639089
Moser von Filseck J and Drin G Running up that hill: How to create cellular lipid gradients by lipid counter-flows. 2016 Biochimie pmid:27519300
Mesmin B and Antonny B The counterflow transport of sterols and PI4P. 2016 Biochim. Biophys. Acta pmid:26928592
Kentala H et al. OSBP-Related Protein Family: Mediators of Lipid Transport and Signaling at Membrane Contact Sites. 2016 Int Rev Cell Mol Biol pmid:26811291
Ketel K et al. A phosphoinositide conversion mechanism for exit from endosomes. 2016 Nature pmid:26760201
Kim E et al. IPMK: A versatile regulator of nuclear signaling events. 2016 Adv Biol Regul pmid:26682649
Domingues L et al. The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells. 2016 Cell. Microbiol. pmid:26676327
Dong N et al. Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector. 2016 Nat Microbiol pmid:27941800
Zhang J et al. Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy. 2016 Int. J. Biochem. Cell Biol. pmid:26589722
Simon ML et al. A PtdIns(4)P-driven electrostatic field controls cell membrane identity and signalling in plants. 2016 Nat Plants pmid:27322096
Yin P et al. A role for retromer in hepatitis C virus replication. 2016 Cell. Mol. Life Sci. pmid:26298293
Alli-Balogun GO et al. Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype. 2016 Mol. Biol. Cell pmid:27798239
Xing M et al. GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. 2016 Mol. Biol. Cell pmid:27708138
Tsutsui Y et al. Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src. 2015 Biochemistry pmid:25961473
Stalder D and Novick PJ Assaying the interaction of the Rab guanine nucleotide exchange protein Sec2 with the upstream Rab, a downstream effector, and a phosphoinositide. 2015 Methods Mol. Biol. pmid:25800834
Moser von Filseck J et al. A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes. 2015 Nat Commun pmid:25849868
Okazaki K et al. Phosphatidylinositol 4-phosphate negatively regulates chloroplast division in Arabidopsis. 2015 Plant Cell pmid:25736058
Adhikari H and Cullen PJ Role of phosphatidylinositol phosphate signaling in the regulation of the filamentous-growth mitogen-activated protein kinase pathway. 2015 Eukaryotic Cell pmid:25724886