phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with phosphatidylinositol-4-phosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

Download all related citations
Per page 10 20 50 100 | Total 500
Authors Title Published Journal PubMed Link
Missiaen L et al. Role of arginine residues in the stimulation of the smooth-muscle plasma-membrane Ca2+ pump by negatively charged phospholipids. 1989 Biochem. J. pmid:2557845
Bryckaert MC et al. Collagen-induced binding to human platelets of platelet-derived growth factor leading to inhibition of P43 and P20 phosphorylation. 1989 J. Biol. Chem. pmid:2538439
Smith CD and Chang KJ Regulation of brain phosphatidylinositol-4-phosphate kinase by GTP analogues. A potential role for guanine nucleotide regulatory proteins. 1989 J. Biol. Chem. pmid:2536738
Kato H et al. Activation of phosphatidylinositol kinase and phosphatidylinositol-4-phosphate kinase by cAMP in Saccharomyces cerevisiae. 1989 J. Biol. Chem. pmid:2536734
Sahyoun NE et al. A synaptosomal protein kinase is regulated by phosphatidylinositol 4-phosphate and Mg2+. 1989 J. Biol. Chem. pmid:2536015
Subramoniam A et al. Influence of trichloroethylene treatment on phosphoinositides in rat brain. 1989 Toxicol. Lett. pmid:2554538
Jarvis WD et al. Attenuation of anterior pituitary phosphoinositide phosphorylase activity by the D2 dopamine receptor. 1988 Endocrinology pmid:2904359
Chauhan VP and Brockerhoff H Phosphatidylinositol-4,5-bisphosphate may antecede diacylglycerol as activator of protein kinase C. 1988 Biochem. Biophys. Res. Commun. pmid:2843176
Saha AK et al. Legionella micdadei phosphatase catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate in human neutrophils. 1988 Arch. Biochem. Biophys. pmid:2843104
Van Paridon PA et al. The effect of polyphosphoinositides and phosphatidic acid on the phosphatidylinositol transfer protein from bovine brain: a kinetic study. 1988 Biochim. Biophys. Acta pmid:2840959
Lo TN et al. Cardiotoxin from cobra venom increases the level of phosphatidylinositol 4-monophosphate and phosphatidylinositol kinase activity in two cell lines. 1988 Biochim. Biophys. Acta pmid:2453219
Whitman M et al. Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. 1988 Nature pmid:2833705
Pike MC and Arndt C Characterization of phosphatidylinositol and phosphatidylinositol-4-phosphate kinases in human neutrophils. 1988 J. Immunol. pmid:2831274
Jímenez B et al. Regulation of diacylglycerol kinase in the transition from quiescence to proliferation in Dictyostelium discoideum. 1988 Biochem. Biophys. Res. Commun. pmid:2827662
Yanagisawa K et al. Localization of phosphatidylinositol 4,5-diphosphate on the stereocilia of cochlear hair cells. 1988 Prog. Brain Res. pmid:2847238
Fukui T et al. Purification of a phospholipase C from rat liver cytosol that acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate. 1988 J. Biol. Chem. pmid:2846577
Smith CD and Snyderman R Modulation of inositol phospholipid metabolism by polyamines. 1988 Biochem. J. pmid:2851975
Berti A et al. Effect of exogenously added acylphosphatases on inositol lipid metabolism in human platelets. 1988 FEBS Lett. pmid:2841154
Steen VM et al. Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism. 1988 Biochem. J. pmid:2845924
Einspahr KJ et al. Rapid changes in polyphosphoinositide metabolism associated with the response of Dunaliella salina to hypoosmotic shock. 1988 J. Biol. Chem. pmid:2833516
Giraud F et al. Stimulation of polyphosphoinositide turnover upon activation of protein kinases in human erythrocytes. 1988 Biochim. Biophys. Acta pmid:2830906
Natarajan V and Schmid HH Inositol phospholipid hydrolysis by rat sciatic nerve phospholipase C. 1987 J. Neurochem. pmid:2824695
Lundberg GA et al. Activation of phosphatidylinositol-4-phosphate kinase in rat liver plasma membranes by polyamines. 1987 Biochim. Biophys. Acta pmid:2822135
Riozzi A et al. Erythrocyte phosphoinositide metabolism in essential hypertensive patients and their normotensive offspring. 1987 Clin. Sci. pmid:3038455
Stokes CE and Hawthorne JN Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains. 1987 J. Neurochem. pmid:3029323
Ochi S et al. Phosphoinositide turnover enhanced by angiotensin II in isolated rat glomeruli. 1987 Biochim. Biophys. Acta pmid:3024736
O'Brian CA et al. The activation of protein kinase C by the polyphosphoinositides phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-monophosphate. 1987 FEBS Lett. pmid:3032687
Schäfer M et al. Ca2+ regulation of 1-(3-sn-phosphatidyl)-1D-myo-inositol 4-phosphate formation and hydrolysis on sarcoplasmic-reticular Ca2+-transport ATPase. A new principle of phospholipid turnover regulation. 1987 Biochem. J. pmid:2827632
Alving BM et al. Lupus anticoagulant activities of murine monoclonal antibodies to liposomal phosphatidylinositol phosphate. 1987 Clin. Exp. Immunol. pmid:2820640
English D et al. Relationship of phosphatidylinositol bisphosphate hydrolysis to calcium mobilization and functional activation in fluoride-treated neutrophils. 1987 J. Clin. Invest. pmid:3036911
Verhoeven AJ et al. Turnover of the phosphomonoester groups of polyphosphoinositol lipids in unstimulated human platelets. 1987 Eur. J. Biochem. pmid:3036523
Verhoeven AJ et al. Stimulation of phosphate uptake in human platelets by thrombin and collagen. Changes in specific 32P labeling of metabolic ATP and polyphosphoinositides. 1987 J. Biol. Chem. pmid:3034877
Hegewald H et al. Influence of Ca2+ and Mg2+ on the turnover of the phosphomonoester group of phosphatidylinositol 4-phosphate in human erythrocyte membranes. 1987 Biochem. J. pmid:2821996
Enyedi A et al. The maximal velocity and the calcium affinity of the red cell calcium pump may be regulated independently. 1987 J. Biol. Chem. pmid:3032968
Bonvini E et al. Interleukin 2 rapidly stimulates synthesis and breakdown of polyphosphoinositides in interleukin 2-dependent, murine T-cell lines. 1987 J. Biol. Chem. pmid:3031064
Whipps DE et al. Effects of glucagon and Ca2+ on the metabolism of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in isolated rat hepatocytes and plasma membranes. 1987 Biochem. J. pmid:3036077
MacDonald ML et al. Regulation of phosphoinositide phosphorylation in Swiss 3T3 cells stimulated by platelet-derived growth factor. 1987 J. Biol. Chem. pmid:3027078
Pike LJ and Eakes AT Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and the breakdown of polyphosphoinositides in A431 cells. 1987 J. Biol. Chem. pmid:2433285
Berti-Mattera LN et al. Insulin reverses enhanced incorporation of 32P into polyphosphoinositides in peripheral nerve of the streptozotocin diabetic rat. 1986 J. Neurochem. pmid:3021909
Tysnes OB et al. Phosphate turnover of phosphatidylinositol in resting and thrombin-stimulated platelets. 1986 Biochim. Biophys. Acta pmid:3022825
Gallo-Payet N et al. Vasopressin induces breakdown of membrane phosphoinositides in adrenal glomerulosa and fasciculata cells. 1986 Endocrinology pmid:3015563
O'Shea JJ et al. Identification and characterization of the phosphatidylinositol kinase in membranes of murine T lymphocytes. 1986 J. Immunol. pmid:3014004
Giusto NM and Ilincheta de Boschero MG Synthesis of polyphosphoinositides in vertebrate photoreceptor membranes. 1986 Biochim. Biophys. Acta pmid:3015222
van Paridon PA et al. Polyphosphoinositides undergo charge neutralization in the physiological pH range: a 31P-NMR study. 1986 Biochim. Biophys. Acta pmid:3013316
Chauhan VP and Brockerhoff H Phosphorylation of erythrocyte membrane liberates calcium. 1986 Biochem. Biophys. Res. Commun. pmid:3010966
Plantavid M et al. Studies of endogenous polyphosphoinositide hydrolysis in human platelet membranes. Evidence that polyphosphoinositides remain inaccessible to phosphodiesterase in the native membrane. 1986 Biochim. Biophys. Acta pmid:3002480
Van Rooijen LA and Bazan NG Cationic amphiphilic drugs perturb the metabolism of inosititides and phosphatidic acid in photoreceptor membranes. 1986 Biochem. Biophys. Res. Commun. pmid:3004440
Gershengorn MC Mechanism of thyrotropin releasing hormone stimulation of pituitary hormone secretion. 1986 Annu. Rev. Physiol. pmid:3010825
de Chaffoy de Courcelles D et al. Agents that elevate platelet cAMP stimulate the formation of phosphatidylinositol 4-phosphate in intact human platelets. 1986 FEBS Lett. pmid:2417883
Kurosawa M and Parker CW A phosphatidylinositol kinase in rat mast cell granules. 1986 J. Immunol. pmid:3001180
Brenner-Gati L and Gershengorn MC Effects of thyrotropin-releasing hormone on phosphoinositides and cytoplasmic free calcium in thyrotropic pituitary cells. 1986 Endocrinology pmid:3000732
Holian A Leukotriene B4 stimulation of phosphatidylinositol turnover in macrophages and inhibition by pertussis toxin. 1986 FEBS Lett. pmid:3011502
Imai A et al. Differential regulation by phosphatidylinositol 4,5-bisphosphate of pituitary plasma-membrane and cytosolic phosphoinositide kinases. 1986 Biochem. J. pmid:3028374
Urumow T and Wieland OH Stimulation of phosphatidylinositol 4-phosphate phosphorylation in human placenta membranes by GTP gamma S. 1986 FEBS Lett. pmid:3021533
Palmer S et al. The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytes. 1986 Biochem. J. pmid:3026353
Vickers JD and Mustard JF The phosphoinositides exist in multiple metabolic pools in rabbit platelets. 1986 Biochem. J. pmid:3026351
Philp NJ and Grollman EF Thyrotropin and norepinephrine stimulate the metabolism of phosphoinositides in FRTL-5 thyroid cells. 1986 FEBS Lett. pmid:3013684
Hidalgo C et al. Phosphorylation of phosphatidylinositol by transverse tubule vesicles and its possible role in excitation-contraction coupling. 1986 FEBS Lett. pmid:3013681
Sale GJ et al. Characterization of phosphatidylinositol kinase activity associated with the insulin receptor. 1986 Eur. J. Biochem. pmid:3007126
Vogel S and Hoppe J Polyamines stimulate the phosphorylation of phosphatidylinositol in membranes from A431 cells. 1986 Eur. J. Biochem. pmid:3002795
Hashimoto T et al. Inositol 1,4,5-trisphosphate activates pharmacomechanical coupling in smooth muscle of the rabbit mesenteric artery. 1986 J. Physiol. (Lond.) pmid:3007748
Okano Y et al. Inhibitory action of phorbol myristate acetate on histamine secretion and polyphosphoinositide turnover induced by compound 48/80 in mast cells. 1985 Biochem. Biophys. Res. Commun. pmid:2415122
Raben DM and Cunningham DD Effects of EGF and thrombin on inositol-containing phospholipids of cultured fibroblasts: stimulation of phosphatidylinositol synthesis by thrombin but not EGF. 1985 J. Cell. Physiol. pmid:2999166
Carney DH et al. Phosphoinositides in mitogenesis: neomycin inhibits thrombin-stimulated phosphoinositide turnover and initiation of cell proliferation. 1985 Cell pmid:2992800
Tallant EA and Wallace RW Calmodulin antagonists elevate the levels of 32P-labeled polyphosphoinositides in human platelets. 1985 Biochem. Biophys. Res. Commun. pmid:2994657
Knowles AF and Lawrence CM Enzymatic synthesis and hydrolysis of [32P]phosphatidylinositol phosphate. 1985 Biochem. Biophys. Res. Commun. pmid:2988548
Holian A and Stickle DF Calcium regulation of phosphatidyl inositol turnover in macrophage activation by formyl peptides. 1985 J. Cell. Physiol. pmid:2982888
van Dongen CJ et al. Microdetermination of phosphoinositides in a single extract. 1985 Anal. Biochem. pmid:2984954
Quist E Ca2+-stimulated phospholipid phosphoesterase activities in rabbit erythrocyte membranes. 1985 Arch. Biochem. Biophys. pmid:2981504
Van Rooijen LA and Agranoff BW Inhibition of polyphosphoinositide phosphodiesterase by aminoglycoside antibiotics. 1985 Neurochem. Res. pmid:2997640
Smith CD et al. Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes. Requirement for a guanine nucleotide regulatory protein. 1985 J. Biol. Chem. pmid:2987206
Watson SP and Lapetina EG 1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:2986126
Taylor D et al. Insulin and epidermal growth factor do not affect phosphoinositide metabolism in rat liver plasma membranes and hepatocytes. 1985 J. Biol. Chem. pmid:2982801
Van Rooijen LA et al. Tetraenoic species are conserved in muscarinically enhanced inositide turnover. 1985 J. Neurochem. pmid:2981288
Wilson DB et al. Phosphoinositide interconversion in thrombin-stimulated human platelets. 1985 J. Biol. Chem. pmid:2981829
Volpi M et al. Phorbol 12-myristate, 13-acetate potentiates the action of the calcium ionophore in stimulating arachidonic acid release and production of phosphatidic acid in rabbit neutrophils. 1985 Biochem. Biophys. Res. Commun. pmid:2986620
Cockcroft S et al. Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils. 1985 FEBS Lett. pmid:2982660
Le Peuch Cj et al. Parthenogenetic activation decreases the polyphosphoinositide content of frog eggs. 1985 FEBS Lett. pmid:2991011
Farkas G et al. Cyclic AMP-dependent protein kinase stimulates the phosphorylation of phosphatidylinositol to phosphatidylinositol-4-monophosphate in a plasma membrane preparation from pig granulocytes. 1984 Biochem. Biophys. Res. Commun. pmid:6095827
de Chaffoy de Courcelles D et al. 1-Oleoyl-2-acetyl-glycerol (OAG) stimulates the formation of phosphatidylinositol 4-phosphate in intact human platelets. 1984 Biochem. Biophys. Res. Commun. pmid:6091634
Graff G et al. Possible regulation of phospholipase C activity in human platelets by phosphatidylinositol 4',5'-bisphosphate. 1984 Arch. Biochem. Biophys. pmid:6320736
Deshmukh DS et al. Mutual stimulation by phosphatidylinositol-4-phosphate and myelin basic protein of their phosphorylation by the kinases solubilized from rat brain myelin. 1984 Life Sci. pmid:6198580
Kolesnick RN and Gershengorn MC Ca2+ ionophores affect phosphoinositide metabolism differently than thyrotropin-releasing hormone in GH3 pituitary cells. 1984 J. Biol. Chem. pmid:6086636
Smith CD and Wells WW Characterization of a phosphatidylinositol 4-phosphate-specific phosphomonoesterase in rat liver nuclear envelopes. 1984 Arch. Biochem. Biophys. pmid:6097190
Enyedi A et al. Cyclic AMP-dependent protein kinase and Ca2+-calmodulin stimulate the formation of polyphosphoinositides in a sarcoplasmic reticulum preparation of rabbit heart. 1984 FEBS Lett. pmid:6092135
Seyfred MA and Wells WW Subcellular incorporation of 32P into phosphoinositides and other phospholipids in isolated hepatocytes. 1984 J. Biol. Chem. pmid:6330069
Wassef NM et al. Suppression of phagocytic function and phospholipid metabolism in macrophages by phosphatidylinositol liposomes. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6326135
Tooke NE et al. Ca2+-sensitive phosphatidylinositol 4-phosphate metabolism in a rat beta-cell tumour. 1984 Biochem. J. pmid:6331389
Vickers JD et al. Changes in the platelet phosphoinositides during the first minute after stimulation of washed rabbit platelets with thrombin. 1984 Biochem. J. pmid:6326756
Hawkins PT et al. Analysis of the metabolic turnover of the individual phosphate groups of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate. Validation of novel analytical techniques by using 32P-labelled lipids from erythrocytes. 1984 Biochem. J. pmid:6326746
Halenda SP and Feinstein MB Phorbol myristate acetate stimulates formation of phosphatidyl inositol 4-phosphate and phosphatidyl inositol 4,5-bisphosphate in human platelets. 1984 Biochem. Biophys. Res. Commun. pmid:6093804
Ishizuka Y et al. Polyphosphoinositide turnover in rat mast cells stimulated by antigen: rapid and preferential breakdown of phosphatidylinositol 4-phosphate (DPI). 1984 Biochem. Biophys. Res. Commun. pmid:6091652
Volpi M et al. Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils. 1983 Biochem. Biophys. Res. Commun. pmid:6303343
Creba JA et al. Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones. 1983 Biochem. J. pmid:6309153
Downes P and Michell RH Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: lipids in search of a function. 1982 Cell Calcium pmid:6297743
pmid:
Kirk CJ et al. Hormone-mediated inositol lipid breakdown in hepatocytes and WRK1 cells: relationship to receptor function. Biochimie pmid:2866800
Tan J and Brill JA Cinderella story: PI4P goes from precursor to key signaling molecule. Crit. Rev. Biochem. Mol. Biol. pmid:24219382
Deli D et al. Deficiency in lysosomal enzyme secretion is associated with upregulation of phosphatidylinositol 4-phosphate in tetrahymena. J. Eukaryot. Microbiol. pmid:18681848
Celadon M et al. Influence of chronic ethanol consumption on the inositol phospholipid fatty acid composition of human peripheral blood lymphocytes. Immunol. Lett. pmid:1336764