phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Tavoosi N et al. Factor VII and protein C are phosphatidic acid-binding proteins. 2013 Biochemistry pmid:23879866
Huang Z et al. Regulation of type II phosphatidylinositol phosphate kinase by tyrosine phosphorylation in bovine rod outer segments. 2001 Biochemistry pmid:11294622
Tsutsui Y et al. Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src. 2015 Biochemistry pmid:25961473
Andersen JF and Ribeiro JM A secreted salivary inositol polyphosphate 5-phosphatase from a blood-feeding insect: allosteric activation by soluble phosphoinositides and phosphatidylserine. 2006 Biochemistry pmid:16634626
Hollenback D and Glomset JA On the relation between a stearoyl-specific transacylase from bovine testis membranes and a copurifying acyltransferase. 1998 Biochemistry pmid:9425058
Yoshida A et al. Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membrane. 2017 Biochim Biophys Acta Biomembr pmid:28648675
Mukherjee P et al. Lipid and membrane recognition by the oxysterol binding protein and its phosphomimetic mutant using dual polarization interferometry. 2018 Biochim Biophys Acta Biomembr pmid:29879417
Van Paridon PA et al. The effect of polyphosphoinositides and phosphatidic acid on the phosphatidylinositol transfer protein from bovine brain: a kinetic study. 1988 Biochim. Biophys. Acta pmid:2840959
Lo TN et al. Cardiotoxin from cobra venom increases the level of phosphatidylinositol 4-monophosphate and phosphatidylinositol kinase activity in two cell lines. 1988 Biochim. Biophys. Acta pmid:2453219
Lundberg GA et al. Activation of phosphatidylinositol-4-phosphate kinase in rat liver plasma membranes by polyamines. 1987 Biochim. Biophys. Acta pmid:2822135
Ochi S et al. Phosphoinositide turnover enhanced by angiotensin II in isolated rat glomeruli. 1987 Biochim. Biophys. Acta pmid:3024736
Tysnes OB et al. Phosphate turnover of phosphatidylinositol in resting and thrombin-stimulated platelets. 1986 Biochim. Biophys. Acta pmid:3022825
Giusto NM and Ilincheta de Boschero MG Synthesis of polyphosphoinositides in vertebrate photoreceptor membranes. 1986 Biochim. Biophys. Acta pmid:3015222
van Paridon PA et al. Polyphosphoinositides undergo charge neutralization in the physiological pH range: a 31P-NMR study. 1986 Biochim. Biophys. Acta pmid:3013316
Mesmin B and Antonny B The counterflow transport of sterols and PI4P. 2016 Biochim. Biophys. Acta pmid:26928592
Yoshida A et al. Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane. 2016 Biochim. Biophys. Acta pmid:26972044
Giraud F et al. Stimulation of polyphosphoinositide turnover upon activation of protein kinases in human erythrocytes. 1988 Biochim. Biophys. Acta pmid:2830906
Björk J and Backman L Sodium selenite as modulator of red cell shape. 1994 Biochim. Biophys. Acta pmid:8155668
Katakami Y et al. Isolation of the phosphatidylinositol 4-monophosphate dissociable high-affinity profilin-actin complex. 1992 Biochim. Biophys. Acta pmid:1322701
Gascard P et al. Asymmetric distribution of phosphoinositides and phosphatidic acid in the human erythrocyte membrane. 1991 Biochim. Biophys. Acta pmid:1657164