phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Yavari A et al. Role of lipid metabolism in smoothened derepression in hedgehog signaling. 2010 Dev. Cell pmid:20643350
Schoebel S et al. High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA. 2010 EMBO Rep. pmid:20616805
Cheong FY et al. Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity. 2010 Traffic pmid:20573065
Dumaresq-Doiron K et al. The phosphatidylinositol 4-kinase PI4KIIIalpha is required for the recruitment of GBF1 to Golgi membranes. 2010 J. Cell. Sci. pmid:20530568
Moorhead AM et al. Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion. 2010 Infect. Immun. pmid:20231409
Gloor Y et al. Interaction between Sec7p and Pik1p: the first clue for the regulation of a coincidence detection signal. 2010 Eur. J. Cell Biol. pmid:20434792
Gonorazky G et al. Involvement of phospholipase C in the responses triggered by extracellular phosphatidylinositol 4-phosphate. 2010 J. Plant Physiol. pmid:19889473
Wood CS et al. PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. 2009 J. Cell Biol. pmid:20026658
Yui N et al. FAPP2 is required for aquaporin-2 apical sorting at trans-Golgi network in polarized MDCK cells. 2009 Am. J. Physiol., Cell Physiol. pmid:19794145
Pantazopoulou A and Peñalva MA Organization and dynamics of the Aspergillus nidulans Golgi during apical extension and mitosis. 2009 Mol. Biol. Cell pmid:19692566
Chan MW et al. FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin. 2009 J. Cell. Sci. pmid:19596799
Qin Y et al. Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. 2009 J. Biol. Chem. pmid:19561074
Schill NJ and Anderson RA Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting. 2009 Biochem. J. pmid:19548880
Hammond GR et al. Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2). 2009 Biochem. J. pmid:19508231
Korzeniowski MK et al. Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides. 2009 J. Biol. Chem. pmid:19483082
Jović M et al. Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling. 2009 Mol. Biol. Cell pmid:19369419
Luo R et al. Arf GAP2 is positively regulated by coatomer and cargo. 2009 Cell. Signal. pmid:19296914
Brice SE et al. Modulation of sphingolipid metabolism by the phosphatidylinositol-4-phosphate phosphatase Sac1p through regulation of phosphatidylinositol in Saccharomyces cerevisiae. 2009 J. Biol. Chem. pmid:19139096
Brombacher E et al. Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. 2009 J. Biol. Chem. pmid:19095644
Vermeer JE et al. Imaging phosphatidylinositol 4-phosphate dynamics in living plant cells. 2009 Plant J. pmid:18785997
Matyas GR et al. Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid epitopes. 2009 AIDS pmid:19710597
Saavedra L et al. Characterization of phosphatidylinositol phosphate kinases from the moss Physcomitrella patens: PpPIPK1 and PpPIPK2. 2009 Plant Cell Physiol. pmid:19188261
Leber W et al. A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum. 2009 Int. J. Parasitol. pmid:19171150
Kuehnel MP et al. Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen. 2009 J. Cell. Sci. pmid:19174471
Baird D et al. Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. 2008 J. Cell Biol. pmid:19075114
Farhan H et al. Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load. 2008 EMBO J. pmid:18650939
D'Angelo G et al. The multiple roles of PtdIns(4)P -- not just the precursor of PtdIns(4,5)P2. 2008 J. Cell. Sci. pmid:18525025
Nakamura T et al. PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex. 2008 Genes Dev. pmid:18451111
Gonorazky G et al. Phosphatidylinositol 4-phosphate accumulates extracellularly upon xylanase treatment in tomato cell suspensions. 2008 Plant Cell Environ. pmid:18419735
Blagoveshchenskaya A et al. Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1. 2008 J. Cell Biol. pmid:18299350
Demmel L et al. The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit. 2008 Mol. Biol. Cell pmid:18287542
Stenzel I et al. The type B phosphatidylinositol-4-phosphate 5-kinase 3 is essential for root hair formation in Arabidopsis thaliana. 2008 Plant Cell pmid:18178770
Choi Y et al. Phosphatidylinositol 3- and 4-phosphate modulate actin filament reorganization in guard cells of day flower. 2008 Plant Cell Environ. pmid:18088331
Balla A et al. Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha. 2008 Mol. Biol. Cell pmid:18077555
Szymańska E et al. Expression of PI(4,5)P2-binding proteins lowers the PI(4,5)P2level and inhibits FcgammaRIIA-mediated cell spreading and phagocytosis. 2008 Eur. J. Immunol. pmid:18050271
Baughman C et al. Nucleoside diphosphate kinase B (NDKB) scaffolds endoplasmic reticulum membranes in vitro. 2008 Exp. Cell Res. pmid:18601920
Zhai C et al. Ypp1/YGR198w plays an essential role in phosphoinositide signalling at the plasma membrane. 2008 Biochem. J. pmid:18601652
Alving CR and Rao M Lipid A and liposomes containing lipid A as antigens and adjuvants. 2008 Vaccine pmid:18226433
Fairn GD et al. The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17881569
Vorwerk S et al. EDR2 negatively regulates salicylic acid-based defenses and cell death during powdery mildew infections of Arabidopsis thaliana. 2007 BMC Plant Biol. pmid:17612410
Stahelin RV et al. Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity. 2007 J. Biol. Chem. pmid:17581820
Wang J et al. PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. 2007 Mol. Biol. Cell pmid:17494868
Jeganathan S and Lee JM Binding of elongation factor eEF1A2 to phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation. 2007 J. Biol. Chem. pmid:17088255
D'Angelo G et al. Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. 2007 Nature pmid:17687330
Posada V et al. Maximal Ca2+i stimulation of cardiac Na+/Ca2+ exchange requires simultaneous alkalinization and binding of PtdIns-4,5-P2 to the exchanger. 2007 Biol. Chem. pmid:17338635
König S et al. Stress-inducible and constitutive phosphoinositide pools have distinctive fatty acid patterns in Arabidopsis thaliana. 2007 FASEB J. pmid:17327357
Beck Z et al. Calcium modulation of monoclonal antibody binding to phosphatidylinositol phosphate. 2007 Biochem. Biophys. Res. Commun. pmid:17257584
Jarquin-Pardo M et al. Phosphatidic acid regulates the affinity of the murine phosphatidylinositol 4-phosphate 5-kinase-Ibeta for phosphatidylinositol-4-phosphate. 2007 J. Cell. Biochem. pmid:16888807
Blumental-Perry A et al. Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER export. 2006 Dev. Cell pmid:17084359
Baust T et al. Proteomic analysis of adaptor protein 1A coats selectively assembled on liposomes. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16492770