| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Foti M et al. | Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. | 2001 | Mol. Biol. Cell | pmid:11514624 |
| Monks DE et al. | Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol transfer protein homolog through activation of the protein kinases SPK1 and SPK2. | 2001 | Plant Cell | pmid:11340192 |
| Hsu FF and Turk J | Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study. | 2000 | J. Am. Soc. Mass Spectrom. | pmid:11073262 |
| Arcaro A et al. | Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors. | 2000 | Mol. Cell. Biol. | pmid:10805725 |
| Frohman MA et al. | Regulation of phospholipase D1 activity by Rho GTPases. | 2000 | Meth. Enzymol. | pmid:11036603 |
| Tharmapathy P et al. | The stimulatory effects of cationic amphiphilic drugs on human platelets treated with thrombin. | 2000 | Biochem. Pharmacol. | pmid:11008120 |
| Baukrowitz T and Fakler B | K(ATP) channels: linker between phospholipid metabolism and excitability. | 2000 | Biochem. Pharmacol. | pmid:10930527 |
| Gonzalez-Agosti C et al. | Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF. | 1999 | J. Biol. Chem. | pmid:10567424 |
| Hama H et al. | Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. | 1999 | J. Biol. Chem. | pmid:10567405 |
| Sorensen SD et al. | Inhibition of beta(2)-adrenergic and muscarinic cholinergic receptor endocytosis after depletion of phosphatidylinositol bisphosphate. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10411568 |
| Rivas MP et al. | Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. | 1999 | Mol. Biol. Cell | pmid:10397762 |
| Kim D and Bang H | Modulation of rat atrial G protein-coupled K+ channel function by phospholipids. | 1999 | J. Physiol. (Lond.) | pmid:10226149 |
| Stock SD et al. | SEC14-dependent secretion in Saccharomyces cerevisiae. Nondependence on sphingolipid synthesis-coupled diacylglycerol production. | 1999 | J. Biol. Chem. | pmid:10224046 |
| Basu SS et al. | A phosphotransferase that generates phosphatidylinositol 4-phosphate (PtdIns-4-P) from phosphatidylinositol and lipid A in Rhizobium leguminosarum. A membrane-bound enzyme linking lipid a and ptdins-4-p biosynthesis. | 1999 | J. Biol. Chem. | pmid:10196199 |
| Zhainazarov AB and Ache BW | Effects of phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate on a Na+-gated nonselective cation channel. | 1999 | J. Neurosci. | pmid:10191310 |
| Nagano K et al. | A novel phospholipase C delta4 (PLCdelta4) splice variant as a negative regulator of PLC. | 1999 | J. Biol. Chem. | pmid:9915823 |
| RÃpová D et al. | Phosphoinositide signalling system in platelets of schizophrenic patients and the effect of neuroleptic therapy. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10509868 |
| Neri LM et al. | Monocytic differentiation of HL-60 cells is characterized by the nuclear translocation of phosphatidylinositol 3-kinase and of definite phosphatidylinositol-specific phospholipase C isoforms. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10362505 |
| Cooke FT et al. | The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. | 1998 | Curr. Biol. | pmid:9811604 |
| Hinchliffe KA et al. | PIPkins1, their substrates and their products: new functions for old enzymes. | 1998 | Biochim. Biophys. Acta | pmid:9838059 |
| Baukrowitz T et al. | PIP2 and PIP as determinants for ATP inhibition of KATP channels. | 1998 | Science | pmid:9804555 |
| Shyng SL and Nichols CG | Membrane phospholipid control of nucleotide sensitivity of KATP channels. | 1998 | Science | pmid:9804554 |
| Wang PY et al. | Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide. | 1998 | J. Biol. Chem. | pmid:9733716 |
| Stevenson JM et al. | A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. | 1998 | J. Biol. Chem. | pmid:9712908 |
| Waugh MG et al. | Phosphatidylinositol 4-phosphate synthesis in immunoisolated caveolae-like vesicles and low buoyant density non-caveolar membranes. | 1998 | J. Biol. Chem. | pmid:9642278 |
| Willars GB et al. | Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells. | 1998 | J. Biol. Chem. | pmid:9478953 |
| Linseman DA et al. | Cytoskeletal and phosphoinositide requirements for muscarinic receptor signaling to focal adhesion kinase and paxillin. | 1998 | J. Neurochem. | pmid:9489713 |
| Ryningen A et al. | Elevation of cyclic AMP decreases phosphoinositide turnover and inhibits thrombin-induced secretion in human platelets. | 1998 | Biochim. Biophys. Acta | pmid:9795233 |
| Guilherme A et al. | A novel phosphorylated lipid counteracts activation of the renal plasma membrane (Ca2+ + Mg2+)ATPase by endogenous phosphatidylinositol-4-phosphate. | 1998 | Biosci. Rep. | pmid:9743476 |
| Lukowski S et al. | Fodrin inhibits phospholipases A2, C, and D by decreasing polyphosphoinositide cell content. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9675127 |
| Hollenback D and Glomset JA | On the relation between a stearoyl-specific transacylase from bovine testis membranes and a copurifying acyltransferase. | 1998 | Biochemistry | pmid:9425058 |
| Cheng CH | In vitro and in vivo inhibitory actions of morin on rat brain phosphatidylinositolphosphate kinase activity. | 1997 | Life Sci. | pmid:9366511 |
| Sun SH et al. | Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells. | 1997 | Lipids | pmid:9076664 |
| Rameh LE et al. | A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. | 1997 | Nature | pmid:9367159 |
| Müller E et al. | Dependence on intracellular Ca2+ on mass and turnover of phosphoinositides and phosphatidate in human erythrocytes. | 1997 | Biol. Chem. | pmid:9348118 |
| Mani I et al. | Increased formation of phosphatidylinositol-4-phosphate in human platelets stimulated with lysophosphatidic acid. | 1996 | Lipids | pmid:8972459 |
| Filtz TM et al. | Purification and G protein subunit regulation of a phospholipase C-beta from Xenopus laevis oocytes. | 1996 | J. Biol. Chem. | pmid:8940109 |
| Isenberg G et al. | Probing phosphatidylinositolphosphates and adenosinenucleotides on talin nucleated actin polymerization. | 1996 | FEBS Lett. | pmid:8955371 |
| Salim K et al. | Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. | 1996 | EMBO J. | pmid:8947047 |
| DebBurman SK et al. | G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. | 1996 | J. Biol. Chem. | pmid:8798423 |
| Molz L et al. | Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain. | 1996 | J. Biol. Chem. | pmid:8662856 |
| Tong W and Sun GY | Effects of ethanol on phosphorylation of lipids in rat synaptic plasma membranes. | 1996 | Alcohol. Clin. Exp. Res. | pmid:8947307 |
| Santavenere E et al. | Sensitivity of Daudi cells to tumor necrosis factor alpha: early changes in polyphosphoinositide metabolism. | 1996 | Cell Biol. Int. | pmid:8948126 |
| Ivanenkov VV et al. | Interaction of S100a0 protein with the actin capping protein, CapZ: characterization of a putative S100a0 binding site in CapZ alpha-subunit. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8660341 |
| Loijens JC et al. | The phosphatidylinositol 4-phosphate 5-kinase family. | 1996 | Adv. Enzyme Regul. | pmid:8869744 |
| Starling AP et al. | Phosphatidylinositol 4-phosphate increases the rate of dephosphorylation of the phosphorylated Ca(2+)-ATPase. | 1995 | J. Biol. Chem. | pmid:7782308 |
| Ding KH and Liang NC | Inhibition of 5'-chloro-5'-deoxyadenosine on phosphoinositide and protein phosphorylation in swine platelets. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7660821 |
| Stack JH et al. | Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. | 1995 | J. Cell Biol. | pmid:7721937 |
| Martelli AM et al. | Inositides in nuclei of Friend cells: changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation. | 1995 | Cell. Signal. | pmid:7756111 |
| Vickers JD | Extraction of polyphosphoinositides from platelets: comparison of a two-step procedure with a common single-step extraction procedure. | 1995 | Anal. Biochem. | pmid:7710110 |
phosphatidylinositol-4-phosphate
phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phosphatidylinositol-4-phosphate?
phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phosphatidylinositol-4-phosphate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phosphatidylinositol-4-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phosphatidylinositol-4-phosphate?
There are no associated biomedical information in the current reference collection.