phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Weber S et al. -Containing Vacuoles Capture PtdIns(4)-Rich Vesicles Derived from the Golgi Apparatus. 2018 MBio pmid:30538188
Melia CE et al. The Origin, Dynamic Morphology, and PI4P-Independent Formation of Encephalomyocarditis Virus Replication Organelles. 2018 MBio pmid:29666283
Sampaio LS et al. Bioactive lipids are altered in the kidney of chronic undernourished rats: is there any correlation with the progression of prevalent nephropathies? 2017 Lipids Health Dis pmid:29246161
Sun SH et al. Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells. 1997 Lipids pmid:9076664
Tong W and Sun GY Phosphorylation of lipids in rat primary glial cells and immortalized astrocytes (DITNC). 1994 Lipids pmid:8090058
Mani I et al. Increased formation of phosphatidylinositol-4-phosphate in human platelets stimulated with lysophosphatidic acid. 1996 Lipids pmid:8972459
Cheng CH In vitro and in vivo inhibitory actions of morin on rat brain phosphatidylinositolphosphate kinase activity. 1997 Life Sci. pmid:9366511
Eng SP and Lo CS Mastoparan increases membrane bound phosphatidylinositol kinase and phosphatidylinositol 4-monophosphate kinase activities in Madin-Darby canine kidney cells. 1990 Life Sci. pmid:2154653
Deshmukh DS et al. Mutual stimulation by phosphatidylinositol-4-phosphate and myelin basic protein of their phosphorylation by the kinases solubilized from rat brain myelin. 1984 Life Sci. pmid:6198580
Wu B et al. Phosphatidylinositol and PI-4-monophosphate recover amyloid beta protein-induced inhibition of Cl- -ATPase activity. 2002 Life Sci. pmid:12467886
Sayyed SG et al. The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins. 2017 Kidney Int. pmid:28302370
Girton RA et al. 15-HETE: selective incorporation into inositol phospholipids of MDCK cells. 1994 Kidney Int. pmid:8007600
Ishikawa-Sasaki K et al. A complex comprising phosphatidylinositol 4-kinase IIIβ, ACBD3, and Aichi virus proteins enhances phosphatidylinositol 4-phosphate synthesis and is critical for formation of the viral replication complex. 2014 J. Virol. pmid:24672044
Li H et al. Hepatitis C virus NS5A hijacks ARFGAP1 to maintain a phosphatidylinositol 4-phosphate-enriched microenvironment. 2014 J. Virol. pmid:24623438
Baird NL et al. Arenavirus infection induces discrete cytosolic structures for RNA replication. 2012 J. Virol. pmid:22875974
Saxena V et al. Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft. 2012 J. Virol. pmid:22301157
Berger KL et al. Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication. 2011 J. Virol. pmid:21697487
Khan I et al. Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2. 2014 J. Virol. pmid:25122779
Ishiyama N et al. The effects of deimination of myelin basic protein on structures formed by its interaction with phosphoinositide-containing lipid monolayers. 2001 J. Struct. Biol. pmid:11858705
Gonorazky G et al. Involvement of phospholipase C in the responses triggered by extracellular phosphatidylinositol 4-phosphate. 2010 J. Plant Physiol. pmid:19889473