phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Wuttke A et al. Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P2 dynamics in secretagogue-stimulated beta-cells. 2010 J. Cell. Sci. pmid:20375060
Minogue S et al. Relationship between phosphatidylinositol 4-phosphate synthesis, membrane organization, and lateral diffusion of PI4KIIalpha at the trans-Golgi network. 2010 J. Lipid Res. pmid:20388919
Szentpetery Z et al. Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20404150
Gloor Y et al. Interaction between Sec7p and Pik1p: the first clue for the regulation of a coincidence detection signal. 2010 Eur. J. Cell Biol. pmid:20434792
Mizuno-Yamasaki E et al. Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p. 2010 Dev. Cell pmid:20493815
Dumaresq-Doiron K et al. The phosphatidylinositol 4-kinase PI4KIIIalpha is required for the recruitment of GBF1 to Golgi membranes. 2010 J. Cell. Sci. pmid:20530568
Cheong FY et al. Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity. 2010 Traffic pmid:20573065
Schoebel S et al. High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA. 2010 EMBO Rep. pmid:20616805
Yavari A et al. Role of lipid metabolism in smoothened derepression in hedgehog signaling. 2010 Dev. Cell pmid:20643350
Lorente-Rodríguez A and Barlowe C Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments. 2011 Mol. Biol. Cell pmid:21119004
Waugh MG et al. Detergent-free isolation and characterization of cholesterol-rich membrane domains from trans-Golgi network vesicles. 2011 J. Lipid Res. pmid:21191144
Santiago-Tirado FH et al. PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast. 2011 Dev. Cell pmid:21238924
Reiss S et al. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. 2011 Cell Host Microbe pmid:21238945
Lenoir M et al. Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1. 2011 Biomol NMR Assign pmid:21298564
Shen B et al. Protein targeting to exosomes/microvesicles by plasma membrane anchors. 2011 J. Biol. Chem. pmid:21300796
Malhotra V and Campelo F PKD regulates membrane fission to generate TGN to cell surface transport carriers. 2011 Cold Spring Harb Perspect Biol pmid:21421913
He J et al. Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. 2011 J. Biol. Chem. pmid:21454700
Eng SP and Lo CS Mastoparan increases membrane bound phosphatidylinositol kinase and phosphatidylinositol 4-monophosphate kinase activities in Madin-Darby canine kidney cells. 1990 Life Sci. pmid:2154653
Morris SJ et al. Phosphoinositide metabolism in cultured glioma and neuroblastoma cells: subcellular distribution of enzymes indicate incomplete turnover at the plasma membrane. 1990 Biochim. Biophys. Acta pmid:2156558
Matyas GR and Alving CR Antigen-specific enhancement of natural human IgG antibodies to phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol-4-phosphate, cholesterol, and lipid A by a liposomal vaccine containing lipid A. 2011 Vaccine pmid:21624414