phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Yoshida A et al. Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membrane. 2017 Biochim Biophys Acta Biomembr pmid:28648675
Zhao K and Ridgway ND Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System. 2017 Cell Rep pmid:28564600
Hanes CM et al. Golgi-Associated Protein Kinase C-ε Is Delivered to Phagocytic Cups: Role of Phosphatidylinositol 4-Phosphate. 2017 J. Immunol. pmid:28539432
Smith CD and Snyderman R Modulation of inositol phospholipid metabolism by polyamines. 1988 Biochem. J. pmid:2851975
Yanagisawa K et al. Localization of phosphatidylinositol 4,5-diphosphate on the stereocilia of cochlear hair cells. 1988 Prog. Brain Res. pmid:2847238
Charman M et al. Oxysterol-binding protein recruitment and activity at the endoplasmic reticulum-Golgi interface are independent of Sac1. 2017 Traffic pmid:28471037
Fukui T et al. Purification of a phospholipase C from rat liver cytosol that acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate. 1988 J. Biol. Chem. pmid:2846577
Steen VM et al. Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism. 1988 Biochem. J. pmid:2845924
Acosta-Andrade C et al. Polyamine-RNA-membrane interactions: From the past to the future in biology. 2017 Colloids Surf B Biointerfaces pmid:28456048
Chauhan VP and Brockerhoff H Phosphatidylinositol-4,5-bisphosphate may antecede diacylglycerol as activator of protein kinase C. 1988 Biochem. Biophys. Res. Commun. pmid:2843176
Saha AK et al. Legionella micdadei phosphatase catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate in human neutrophils. 1988 Arch. Biochem. Biophys. pmid:2843104
Berti A et al. Effect of exogenously added acylphosphatases on inositol lipid metabolism in human platelets. 1988 FEBS Lett. pmid:2841154
Van Paridon PA et al. The effect of polyphosphoinositides and phosphatidic acid on the phosphatidylinositol transfer protein from bovine brain: a kinetic study. 1988 Biochim. Biophys. Acta pmid:2840959
Khadka B and Gupta RS Identification of a conserved 8 aa insert in the PIP5K protein in the Saccharomycetaceae family of fungi and the molecular dynamics simulations and structural analysis to investigate its potential functional role. 2017 Proteins pmid:28407364
Whitman M et al. Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. 1988 Nature pmid:2833705
Einspahr KJ et al. Rapid changes in polyphosphoinositide metabolism associated with the response of Dunaliella salina to hypoosmotic shock. 1988 J. Biol. Chem. pmid:2833516
Manik MK et al. Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction. 2017 Structure pmid:28319008
Pike MC and Arndt C Characterization of phosphatidylinositol and phosphatidylinositol-4-phosphate kinases in human neutrophils. 1988 J. Immunol. pmid:2831274
Giraud F et al. Stimulation of polyphosphoinositide turnover upon activation of protein kinases in human erythrocytes. 1988 Biochim. Biophys. Acta pmid:2830906
Azouaoui H et al. High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions. 2017 J. Biol. Chem. pmid:28302728