phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

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Introduction

To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phosphatidylinositol-4-phosphate?

phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phosphatidylinositol-4-phosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:

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What functions are associated with phosphatidylinositol-4-phosphate?


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What lipids are associated with phosphatidylinositol-4-phosphate?

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What genes are associated with phosphatidylinositol-4-phosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phosphatidylinositol-4-phosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with phosphatidylinositol-4-phosphate

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Authors Title Published Journal PubMed Link
Tu L et al. A conserved N-terminal arginine-motif in GOLPH3-family proteins mediates binding to coatomer. 2012 Traffic pmid:22889169
Piao H et al. Metabolic activation of the HOG MAP kinase pathway by Snf1/AMPK regulates lipid signaling at the Golgi. 2012 Traffic pmid:22882253
Baird NL et al. Arenavirus infection induces discrete cytosolic structures for RNA replication. 2012 J. Virol. pmid:22875974
Bishé B et al. Role of phosphatidylinositol 4-phosphate (PI4P) and its binding protein GOLPH3 in hepatitis C virus secretion. 2012 J. Biol. Chem. pmid:22745132
Hammond GR et al. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. 2012 Science pmid:22722250
Jobe O et al. An anti-phosphoinositide-specific monoclonal antibody that neutralizes HIV-1 infection of human monocyte-derived macrophages. 2012 Virology pmid:22633000
Wood CS et al. Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase. 2012 Mol. Biol. Cell pmid:22553352
Boggs JM et al. Effect of phosphorylation of phosphatidylinositol on myelin basic protein-mediated binding of actin filaments to lipid bilayers in vitro. 2012 Biochim. Biophys. Acta pmid:22538354
Lefèbvre F et al. Secretory pathway-dependent localization of the Saccharomyces cerevisiae Rho GTPase-activating protein Rgd1p at growth sites. 2012 Eukaryotic Cell pmid:22447923
Bianco A et al. Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity. 2012 PLoS Pathog. pmid:22412376
Mousley CJ et al. Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate Golgi functionality. 2012 Subcell. Biochem. pmid:22374094
Zhang L et al. ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication. 2012 PLoS ONE pmid:22359663
Jacquot A et al. Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate. 2012 J. Biol. Chem. pmid:22351780
Han WQ et al. Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells. 2012 J. Cell. Sci. pmid:22349696
Daboussi L et al. Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network. 2012 Nat. Cell Biol. pmid:22344030
Saxena V et al. Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft. 2012 J. Virol. pmid:22301157
Levine TP Lipid traffic: Osh4p makes an unexpected exchange. 2011 J. Cell Biol. pmid:22162132
Tai AW and Salloum S The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement. 2011 PLoS ONE pmid:22022594
Martín-Acebes MA et al. West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipids. 2011 PLoS ONE pmid:21949814
He J et al. Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications. 2011 Chem. Biol. pmid:22035800