| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Daboussi L et al. | Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network. | 2012 | Nat. Cell Biol. | pmid:22344030 |
| Sun Y and Drubin DG | Pik1-ing clathrin adaptors. | 2012 | Nat. Cell Biol. | pmid:22344031 |
| Roth M | New candidates for vesicle coat proteins. | 2004 | Nat. Cell Biol. | pmid:15122263 |
| Godi A et al. | FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. | 2004 | Nat. Cell Biol. | pmid:15107860 |
| McNamara CW et al. | Targeting Plasmodium PI(4)K to eliminate malaria. | 2013 | Nature | pmid:24284631 |
| Whitman M et al. | Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. | 1988 | Nature | pmid:2833705 |
| He K et al. | Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic. | 2017 | Nature | pmid:29236694 |
| Ketel K et al. | A phosphoinositide conversion mechanism for exit from endosomes. | 2016 | Nature | pmid:26760201 |
| D'Angelo G et al. | Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. | 2013 | Nature | pmid:23913272 |
| D'Angelo G et al. | Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. | 2007 | Nature | pmid:17687330 |
| Rameh LE et al. | A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. | 1997 | Nature | pmid:9367159 |
| Hanada K et al. | Molecular machinery for non-vesicular trafficking of ceramide. | 2003 | Nature | pmid:14685229 |
| Fukami K et al. | Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function. | 1992 | Nature | pmid:1326084 |
| Park J et al. | Deleterious effects of soluble amyloid-β oligomers on multiple steps of synaptic vesicle trafficking. | 2013 | Neurobiol. Dis. | pmid:23523634 |
| Van Rooijen LA and Agranoff BW | Inhibition of polyphosphoinositide phosphodiesterase by aminoglycoside antibiotics. | 1985 | Neurochem. Res. | pmid:2997640 |
| Li L et al. | A phosphoinositide-specific phospholipase C pathway elicits stress-induced Ca signals and confers salt tolerance to rice. | 2017 | New Phytol. | pmid:28157263 |
| Carloni V et al. | Tetraspanin CD81 is linked to ERK/MAPKinase signaling by Shc in liver tumor cells. | 2004 | Oncogene | pmid:14676841 |
| Furse S et al. | Synthesis of unsaturated phosphatidylinositol 4-phosphates and the effects of substrate unsaturation on SopB phosphatase activity. | 2015 | Org. Biomol. Chem. | pmid:25515724 |
| Baumlova A et al. | The structural basis for calcium inhibition of lipid kinase PI4K IIalpha and comparison with the apo state. | 2016 | Physiol Res | pmid:27539108 |
| Gonorazky G et al. | Phosphatidylinositol 4-phosphate is associated to extracellular lipoproteic fractions and is detected in tomato apoplastic fluids. | 2012 | Plant Biol (Stuttg) | pmid:21972816 |
| Gagne JM and Clark SE | The Arabidopsis stem cell factor POLTERGEIST is membrane localized and phospholipid stimulated. | 2010 | Plant Cell | pmid:20348433 |
| Stenzel I et al. | The type B phosphatidylinositol-4-phosphate 5-kinase 3 is essential for root hair formation in Arabidopsis thaliana. | 2008 | Plant Cell | pmid:18178770 |
| Jung JY et al. | Phosphatidylinositol 3- and 4-phosphate are required for normal stomatal movements. | 2002 | Plant Cell | pmid:12368494 |
| Monks DE et al. | Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol transfer protein homolog through activation of the protein kinases SPK1 and SPK2. | 2001 | Plant Cell | pmid:11340192 |
| Okazaki K et al. | Phosphatidylinositol 4-phosphate negatively regulates chloroplast division in Arabidopsis. | 2015 | Plant Cell | pmid:25736058 |
| Gonorazky G et al. | Phosphatidylinositol 4-phosphate accumulates extracellularly upon xylanase treatment in tomato cell suspensions. | 2008 | Plant Cell Environ. | pmid:18419735 |
| Choi Y et al. | Phosphatidylinositol 3- and 4-phosphate modulate actin filament reorganization in guard cells of day flower. | 2008 | Plant Cell Environ. | pmid:18088331 |
| Zhang Q et al. | Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth. | 2018 | Plant Cell Physiol. | pmid:30107538 |
| Saavedra L et al. | Characterization of phosphatidylinositol phosphate kinases from the moss Physcomitrella patens: PpPIPK1 and PpPIPK2. | 2009 | Plant Cell Physiol. | pmid:19188261 |
| Vermeer JE et al. | Imaging phosphatidylinositol 4-phosphate dynamics in living plant cells. | 2009 | Plant J. | pmid:18785997 |
| Kim YW et al. | Arabidopsis dynamin-like 2 that binds specifically to phosphatidylinositol 4-phosphate assembles into a high-molecular weight complex in vivo and in vitro. | 2001 | Plant Physiol. | pmid:11706203 |
| Jiang K et al. | PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail. | 2016 | PLoS Biol. | pmid:26863604 |
| Zhang L et al. | ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication. | 2012 | PLoS ONE | pmid:22359663 |
| Tai AW and Salloum S | The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement. | 2011 | PLoS ONE | pmid:22022594 |
| MartÃn-Acebes MA et al. | West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipids. | 2011 | PLoS ONE | pmid:21949814 |
| Moriwaki Y et al. | SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes. | 2018 | PLoS ONE | pmid:29953492 |
| Tenorio MJ et al. | Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2016 | PLoS ONE | pmid:27123979 |
| Azouaoui H et al. | A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate. | 2014 | PLoS ONE | pmid:25393116 |
| Liu X and Ridgway ND | Characterization of the sterol and phosphatidylinositol 4-phosphate binding properties of Golgi-associated OSBP-related protein 9 (ORP9). | 2014 | PLoS ONE | pmid:25255026 |
| Bianco A et al. | Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity. | 2012 | PLoS Pathog. | pmid:22412376 |
| Banerjee S et al. | Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. | 2018 | PLoS Pathog. | pmid:29782554 |
| Oh HS et al. | Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides. | 2018 | PLoS Pathog. | pmid:29702686 |
| Weber SS et al. | Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole. | 2006 | PLoS Pathog. | pmid:16710455 |
| Dorobantu CM et al. | Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus. | 2015 | PLoS Pathog. | pmid:26406250 |
| Baust T et al. | Proteomic analysis of adaptor protein 1A coats selectively assembled on liposomes. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16492770 |
| Ungewickell A et al. | The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16365287 |
| Walsh JP et al. | Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1656463 |
| Watson SP and Lapetina EG | 1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis. | 1985 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2986126 |
| Sohn M et al. | Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27044099 |
| Jeschke A et al. | Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25825728 |
phosphatidylinositol-4-phosphate
phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of phosphatidylinositol-4-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phosphatidylinositol-4-phosphate?
phosphatidylinositol-4-phosphate is suspected in Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection, Rhinovirus infection, Enterovirus Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phosphatidylinositol-4-phosphate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phosphatidylinositol-4-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phosphatidylinositol-4-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phosphatidylinositol-4-phosphate?
There are no associated biomedical information in the current reference collection.