Dioctanoylphosphatidic acid

Dioctanoylphosphatidic acid is a lipid of Glycerophospholipids (GP) class. The involved functions are known as vesicle-mediated transport, Anabolism, Binding (Molecular Function), Regulation and Stimulus. Dioctanoylphosphatidic acid often locates in Endoplasmic Reticulum, Secretory Vesicles, trans-Golgi Network, Organelles and Membrane. The associated genes with Dioctanoylphosphatidic acid are NCF1 gene, FPR1 gene, neutrophil cytosol factor 67K, neutrophil cytosol factor 40K and THOC4 gene. The related lipids are lysophosphatidic acid, Phosphatidic Acid, dioctanoylphosphatidic acid, phosphatidylpropanol and Phosphatidic Acids.

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Introduction

To understand associated biological information of Dioctanoylphosphatidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dioctanoylphosphatidic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Dioctanoylphosphatidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Dioctanoylphosphatidic acid?

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What functions are associated with Dioctanoylphosphatidic acid?


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What lipids are associated with Dioctanoylphosphatidic acid?

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What genes are associated with Dioctanoylphosphatidic acid?

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What common seen animal models are associated with Dioctanoylphosphatidic acid?

There are no associated biomedical information in the current reference collection.

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All references with Dioctanoylphosphatidic acid

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Authors Title Published Journal PubMed Link
pmid:
Tool AT et al. Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils. 1999 Biochem. J. pmid:10229663
Nobe K et al. Activation of diacylglycerol kinase by carbachol in guinea pig taenia coli. 1994 Biochem. Pharmacol. pmid:7802689
Wang G Determination of solution structure and lipid micelle location of an engineered membrane peptide by using one NMR experiment and one sample. 2007 Biochim. Biophys. Acta pmid:17905196
Violet PC et al. Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK(1/2) MAP kinases. 2012 Biochim. Biophys. Acta pmid:22820196
Gradziel CS et al. d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway. 2016 Biochim. Biophys. Acta pmid:27600289
Durgam GG et al. Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands. 2006 Bioorg. Med. Chem. Lett. pmid:16263282
Nobe K et al. Alternations of diacylglycerol kinase in streptozotocin-induced diabetic rats. 1998 Cell. Signal. pmid:9754714
Berti D et al. Amphiphilic self-assemblies decorated by nucleobases. 2007 J Phys Chem B pmid:17880129
Perry DK et al. A novel ecto-phosphatidic acid phosphohydrolase activity mediates activation of neutrophil superoxide generation by exogenous phosphatidic acid. 1993 J. Biol. Chem. pmid:8244961