| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
Aminoadipic acid
Aminoadipic acid is a lipid of Fatty Acyls (FA) class. Aminoadipic acid is associated with abnormalities such as Diabetes and Proliferative retinopathy NOS. The involved functions are known as Uptake, Process, lysine catabolism, Pressure- physical agent and Proteolysis. Aminoadipic acid often locates in Protoplasm, Chromosomes, Astrocytic, Basal lamina and Cytoplasmic matrix. The associated genes with Aminoadipic acid are Homologous Gene, Excitatory Amino Acids, allysine, Diaminopimelic Acid and Gene Clusters.
Cross Reference
Introduction
To understand associated biological information of Aminoadipic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Aminoadipic acid?
Aminoadipic acid is suspected in Diabetes, Proliferative retinopathy NOS and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Aminoadipic acid
PubChem Associated disorders and diseases
What pathways are associated with Aminoadipic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Aminoadipic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Aminoadipic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Aminoadipic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Aminoadipic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Aminoadipic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Aminoadipic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Aminoadipic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Waghorn PA et al. | High sensitivity HPLC method for determination of the allysine concentration in tissue by use of a naphthol derivative. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28886479 |
| Wang X et al. | α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension. | 2016 | Drug Des Devel Ther | pmid:27799744 |
| Choi M et al. | Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus. | 2016 | Mol Brain | pmid:27460927 |
| Yu WQ et al. | Reshaping the Cone-Mosaic in a Rat Model of Retinitis Pigmentosa: Modulatory Role of ZO-1 Expression in DL-Alpha-Aminoadipic Acid Reshaping. | 2016 | PLoS ONE | pmid:26977812 |
| Li WW et al. | Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture. | 2015 | Neuroscience | pmid:26386297 |
| Yoshida A et al. | Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ·LysW complex from Thermus thermophilus. | 2015 | J. Biol. Chem. | pmid:25392000 |
| Ross AB et al. | Herring and Beef Meals Lead to Differences in Plasma 2-Aminoadipic Acid, β-Alanine, 4-Hydroxyproline, Cetoleic Acid, and Docosahexaenoic Acid Concentrations in Overweight Men. | 2015 | J. Nutr. | pmid:26400963 |
| Gabriel I et al. | Phenotypic consequences of LYS4 gene disruption in Candida albicans. | 2014 | Yeast | pmid:24898203 |
| Sherpa AD et al. | Gliotoxin-induced swelling of astrocytes hinders diffusion in brain extracellular space via formation of dead-space microdomains. | 2014 | Glia | pmid:24687699 |
| Utrera M et al. | Protein oxidation during frozen storage and subsequent processing of different beef muscles. | 2014 | Meat Sci. | pmid:24200575 |
| Arora P | Metabolomics yield a novel biomarker for predicting diabetes mellitus risk in humans. | 2014 | Circ Cardiovasc Genet | pmid:24550433 |
| Ohmichi M et al. | Activated spinal astrocytes are involved in the maintenance of chronic widespread mechanical hyperalgesia after cast immobilization. | 2014 | Mol Pain | pmid:24456903 |
| Sehanobish E et al. | Steady-state kinetic mechanism of LodA, a novel cysteine tryptophylquinone-dependent oxidase. | 2014 | FEBS Lett. | pmid:24462691 |
| Ferrer-López I et al. | Determination of urinary alpha-aminoadipic semialdehyde by LC-MS/MS in patients with congenital metabolic diseases. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24316525 |
| Utrera M et al. | Temperature of frozen storage affects the nature and consequences of protein oxidation in beef patties. | 2014 | Meat Sci. | pmid:24334047 |
| Vogel-Adghough D et al. | Pipecolic acid enhances resistance to bacterial infection and primes salicylic acid and nicotine accumulation in tobacco. | 2013 | Plant Signal Behav | pmid:24025239 |
| Ouchi T et al. | Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus. | 2013 | Nat. Chem. Biol. | pmid:23434852 |
| Villaverde A and Estévez M | Carbonylation of myofibrillar proteins through the maillard pathway: effect of reducing sugars and reaction temperature. | 2013 | J. Agric. Food Chem. | pmid:23438261 |
| Lee Y et al. | Glutamine deficiency in the prefrontal cortex increases depressive-like behaviours in male mice. | 2013 | J Psychiatry Neurosci | pmid:23031251 |
| Ji XT et al. | Spinal astrocytic activation contributes to mechanical allodynia in a rat chemotherapy-induced neuropathic pain model. | 2013 | PLoS ONE | pmid:23585846 |
| Sadiq A and Sewald N | 6-Alkynyl- and 6-aryl-substituted (R)-pipecolic acid derivatives. | 2013 | Org. Lett. | pmid:23718275 |
| Jung S et al. | Preliminary investigation of the use of newborn dried blood spots for screening pyridoxine-dependent epilepsy by LC-MS/MS. | 2013 | Mol. Genet. Metab. | pmid:23953072 |
| Wang TJ et al. | 2-Aminoadipic acid is a biomarker for diabetes risk. | 2013 | J. Clin. Invest. | pmid:24091325 |
| Cao YX et al. | Comparison of the secondary metabolites in two scales of cephalosporin C (CPC) fermentation and two different post-treatment processes. | 2013 | J. Ind. Microbiol. Biotechnol. | pmid:23053347 |
| Leite CA et al. | Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus. | 2013 | BMC Microbiol. | pmid:24359569 |
| Sun ML et al. | Glial modulation of vibrissal sensory processing in rats. | 2013 | Chin J Physiol | pmid:24495177 |
| Yang ZX and Qin J | [Advances in clinical and molecular genetic research on pyridoxine dependent epilepsy]. | 2013 | Zhonghua Er Ke Za Zhi | pmid:24484566 |
| Lorber B et al. | Activated retinal glia mediated axon regeneration in experimental glaucoma. | 2012 | Neurobiol. Dis. | pmid:21867754 |
| Shibata M et al. | Involvement of glial cells in the autoregulation of optic nerve head blood flow in rabbits. | 2012 | Invest. Ophthalmol. Vis. Sci. | pmid:22589427 |
| Mercimek-Mahmutoglu S et al. | Profound neonatal hypoglycemia and lactic acidosis caused by pyridoxine-dependent epilepsy. | 2012 | Pediatrics | pmid:22529283 |
| Struys EA et al. | The measurement of urinary Δ¹-piperideine-6-carboxylate, the alter ego of α-aminoadipic semialdehyde, in Antiquitin deficiency. | 2012 | J. Inherit. Metab. Dis. | pmid:22249334 |
| Nishiyama M | [Regulatory mechanisms of novel lysine biosynthesis in thermophile]. | 2012 | Seikagaku | pmid:22712232 |
| Alfadhel M et al. | Variability of phenotype in two sisters with pyridoxine dependent epilepsy. | 2012 | Can J Neurol Sci | pmid:22728861 |
| Utrera M et al. | Pre-freezing raw hams affects quality traits in cooked hams: potential influence of protein oxidation. | 2012 | Meat Sci. | pmid:22748310 |
| Boniello C et al. | Dual-lifetime referencing (DLR): a powerful method for on-line measurement of internal pH in carrier-bound immobilized biocatalysts. | 2012 | BMC Biotechnol. | pmid:22455624 |
| Vossen E et al. | Dog rose (Rosa canina L.) as a functional ingredient in porcine frankfurters without added sodium ascorbate and sodium nitrite. | 2012 | Meat Sci. | pmid:22698996 |
| Mills PB et al. | Urinary AASA excretion is elevated in patients with molybdenum cofactor deficiency and isolated sulphite oxidase deficiency. | 2012 | J. Inherit. Metab. Dis. | pmid:22403017 |
| Bellance N et al. | Oncosecretomics coupled to bioenergetics identifies α-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1 and KLF4 coordinates metabolic changes. | 2012 | Biochim. Biophys. Acta | pmid:22842522 |
| Struys EA et al. | Pyridoxine-dependent epilepsy with elevated urinary α-amino adipic semialdehyde in molybdenum cofactor deficiency. | 2012 | Pediatrics | pmid:23147983 |
| Fazius F et al. | The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate. | 2012 | Mol. Microbiol. | pmid:23106124 |
| Zhu W et al. | Reactive astrocytes contribute to increased epileptic susceptibility induced by subthreshold dose of pilocarpine. | 2012 | Epilepsy Behav | pmid:23123923 |
| van Karnebeek CD et al. | Lysine restricted diet for pyridoxine-dependent epilepsy: first evidence and future trials. | 2012 | Mol. Genet. Metab. | pmid:23022070 |
| Danhauser K et al. | DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. | 2012 | Am. J. Hum. Genet. | pmid:23141293 |
| Al-Saman AS and Rizk TM | A case of extreme prematurity and delayed diagnosis of pyridoxine-dependent epilepsy. | 2012 | Neurosciences (Riyadh) | pmid:23022904 |
| Machné R and Murray DB | The yin and yang of yeast transcription: elements of a global feedback system between metabolism and chromatin. | 2012 | PLoS ONE | pmid:22685547 |
| Seminoff JA et al. | Stable isotope tracking of endangered sea turtles: validation with satellite telemetry and δ15N analysis of amino acids. | 2012 | PLoS ONE | pmid:22666354 |
| Nishida H and Nishiyama M | Evolution of lysine biosynthesis in the phylum deinococcus-thermus. | 2012 | Int J Evol Biol | pmid:22645699 |
| Nishida H | Comparative analyses of homocitrate synthase genes of ascomycetous yeasts. | 2012 | Int J Evol Biol | pmid:22518332 |
| Bartoszewska M et al. | The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi. | 2011 | Biotechnol. Lett. | pmid:21660569 |
| Shen W et al. | Submacular DL-alpha-aminoadipic acid eradicates primate photoreceptors but does not affect luteal pigment or the retinal vasculature. | 2011 | Invest. Ophthalmol. Vis. Sci. | pmid:20720223 |
| Utrera M et al. | Fluorescent HPLC for the detection of specific protein oxidation carbonyls - α-aminoadipic and γ-glutamic semialdehydes - in meat systems. | 2011 | Meat Sci. | pmid:21641732 |
| Brocker C et al. | Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. | 2011 | Chem. Biol. Interact. | pmid:21338592 |
| Ganesh BS and Chintala SK | Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells. | 2011 | PLoS ONE | pmid:21483783 |
| Sauer SW et al. | Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I. | 2011 | Brain | pmid:20923787 |
| Liao YH et al. | Spinal astrocytic activation contributes to mechanical allodynia in a mouse model of type 2 diabetes. | 2011 | Brain Res. | pmid:20971097 |
| Chan CL et al. | Human antiquitin: structural and functional studies. | 2011 | Chem. Biol. Interact. | pmid:21185811 |
| Lee EJ et al. | Role of Müller cells in cone mosaic rearrangement in a rat model of retinitis pigmentosa. | 2011 | Glia | pmid:21547953 |
| Afiuni-Zadeh S et al. | Optimization and application of microwave-assisted acid hydrolysis for rapid quantification of protein oxidation markers using LC-MS. | 2011 | Talanta | pmid:21872027 |
| Almasi JN et al. | A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase. | 2011 | Molecules | pmid:21993247 |
| Moussawi K et al. | Extracellular glutamate: functional compartments operate in different concentration ranges. | 2011 | Front Syst Neurosci | pmid:22275885 |
| Watanabe M et al. | Molecular phylogeny of the higher and lower taxonomy of the Fusarium genus and differences in the evolutionary histories of multiple genes. | 2011 | BMC Evol. Biol. | pmid:22047111 |
| Siebers B et al. | The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota. | 2011 | PLoS ONE | pmid:22003381 |
| ErdemoÄŸlu M et al. | Amniotic fluid amino acid levels in non-immune hydrops fetalis: a case-control study. | 2011 | Braz. J. Med. Biol. Res. | pmid:21833460 |
| Okuno A et al. | High tryptophan diet reduces extracellular dopamine release via kynurenic acid production in rat striatum. | 2011 | J. Neurochem. | pmid:21711351 |
| El-Sayyad HI et al. | Protective effects of Morus alba leaves extract on ocular functions of pups from diabetic and hypercholesterolemic mother rats. | 2011 | Int. J. Biol. Sci. | pmid:21697998 |
| Zhang H et al. | Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies. | 2011 | PLoS ONE | pmid:21677784 |
| Pampliega O et al. | Increased expression of cystine/glutamate antiporter in multiple sclerosis. | 2011 | J Neuroinflammation | pmid:21639880 |
| Metwally NS et al. | Levels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients. | 2011 | Cancer Cell Int. | pmid:21473769 |
| Zhao Z et al. | Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol. | 2011 | Appl. Microbiol. Biotechnol. | pmid:20809073 |
| Lykidis A et al. | The complete multipartite genome sequence of Cupriavidus necator JMP134, a versatile pollutant degrader. | 2010 | PLoS ONE | pmid:20339589 |
| Mei XP et al. | Combining ketamine with astrocytic inhibitor as a potential analgesic strategy for neuropathic pain ketamine, astrocytic inhibitor and pain. | 2010 | Mol Pain | pmid:20815929 |
| Gao YJ and Ji RR | Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia. | 2010 | J. Neurochem. | pmid:20722971 |
| Johnson TV et al. | Identification of barriers to retinal engraftment of transplanted stem cells. | 2010 | Invest. Ophthalmol. Vis. Sci. | pmid:19850833 |
| Isobe K | Enzymes responsible for metabolism of Nα-benzyloxycarbonyl-L-lysine in microorganisms. | 2010 | N Biotechnol | pmid:20460177 |
| Mills PB et al. | Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency). | 2010 | Brain | pmid:20554659 |
| Isobe K et al. | Enzymes responsible for the conversion of N alpha-[(Benzyloxy)carbonyl]-D-lysine to N alpha-[(Benzyloxy)carbonyl]-D-aminoadipic acid by Rhodococcus sp. AIU Z-35-1. | 2010 | Chem. Biodivers. | pmid:20564569 |
| Feng QX et al. | Astrocytic activation in thoracic spinal cord contributes to persistent pain in rat model of chronic pancreatitis. | 2010 | Neuroscience | pmid:20149842 |
| Kandil S et al. | Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-gamma-lyase and upregulation of the transsulfuration pathway in C6 glioma cells. | 2010 | Neurochem. Int. | pmid:20060865 |
| Shen W et al. | Retinal vascular changes after glial disruption in rats. | 2010 | J. Neurosci. Res. | pmid:20029988 |
| Chavez JD et al. | A targeted mass spectrometry-based approach for the identification and characterization of proteins containing α-aminoadipic and γ-glutamic semialdehyde residues. | 2010 | Anal Bioanal Chem | pmid:20957471 |
| Rellán-Alvarez R et al. | Changes in the proteomic and metabolic profiles of Beta vulgaris root tips in response to iron deficiency and resupply. | 2010 | BMC Plant Biol. | pmid:20565974 |
| Sunnam SK et al. | Bicyclic sigma receptor ligands by stereoselective Dieckmann analogous cyclization of piperazinebutyrate. | 2010 | Org. Biomol. Chem. | pmid:20556273 |
| Khakpay R et al. | Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors. | 2010 | Purinergic Signal. | pmid:21103218 |
| Jaleel A et al. | Identification of de novo synthesized and relatively older proteins: accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetes. | 2010 | Diabetes | pmid:20622162 |
| Han Q et al. | Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases. | 2010 | BMC Biochem. | pmid:20482848 |
| Wang YF and Hatton GI | Astrocytic plasticity and patterned oxytocin neuronal activity: dynamic interactions. | 2009 | J. Neurosci. | pmid:19211881 |
| Kanu A and Leffler CW | Roles of glia limitans astrocytes and carbon monoxide in adenosine diphosphate-induced pial arteriolar dilation in newborn pigs. | 2009 | Stroke | pmid:19164779 |
| Tomita T et al. | Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus. | 2009 | Proteins | pmid:18831049 |
| Estévez M et al. | Analysis of protein oxidation markers alpha-aminoadipic and gamma-glutamic semialdehydes in food proteins using liquid chromatography (LC)-electrospray ionization (ESI)-multistage tandem mass spectrometry (MS). | 2009 | J. Agric. Food Chem. | pmid:19326863 |
| Wang W et al. | Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain. | 2009 | PLoS ONE | pmid:19759893 |
| Akagawa M et al. | Fluorescent detection of alpha-aminoadipic and gamma-glutamic semialdehydes in oxidized proteins. | 2009 | Free Radic. Biol. Med. | pmid:19135526 |
| Park JB et al. | Regulation of tonic GABA inhibitory function, presympathetic neuronal activity and sympathetic outflow from the paraventricular nucleus by astroglial GABA transporters. | 2009 | J. Physiol. (Lond.) | pmid:19703969 |
| Sadilkova K et al. | Simultaneous determination of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate and pipecolic acid by LC-MS/MS for pyridoxine-dependent seizures and folinic acid-responsive seizures. | 2009 | J. Neurosci. Methods | pmid:19631689 |
| Ouchi T et al. | Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19632206 |
| Fan X et al. | Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes. | 2009 | J. Biol. Chem. | pmid:19854833 |
| Wang Y et al. | Systems metabolic effects of a necator americanus infection in Syrian hamster. | 2009 | J. Proteome Res. | pmid:19810771 |
| Miguel-Hidalgo J et al. | Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats. | 2009 | J. Psychopharmacol. (Oxford) | pmid:18562436 |
| Battur B et al. | LKR/SDH plays important roles throughout the tick life cycle including a long starvation period. | 2009 | PLoS ONE | pmid:19774086 |
| Zivanovic Y et al. | Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea. | 2009 | Genome Biol. | pmid:19558674 |
| Bloomgarden ZT | Cardiovascular disease, neuropathy, and retinopathy. | 2009 | Diabetes Care | pmid:19460904 |