Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypercalcemia D006934 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lung Neoplasms D008175 171 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Per page 10 20 50 100 | Total 1061
Authors Title Published Journal PubMed Link
Centeno DC et al. Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. 2011 Plant Cell pmid:21239646
Walther J et al. Hot transcriptomics. 2011 Archaea pmid:21350598
Denton TT et al. Characterization of D-glucaric acid using NMR, X-ray crystal structure, and MM3 molecular modeling analyses. 2011 Carbohydr. Res. pmid:22015400
Bhattacharya S et al. D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway. 2011 Toxicol. Appl. Pharmacol. pmid:21982801
Aspuru K et al. Optimal management of iron deficiency anemia due to poor dietary intake. 2011 Int J Gen Med pmid:22114518
Toblli JE et al. Evaluation of toxicity and oxidative stress induced by intravenous iron isomaltoside 1000 in a nonclinical model. 2011 Arzneimittelforschung pmid:22164963
Menendez C et al. Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed? 2011 Mol Nutr Food Res pmid:22144045
Di Nocera PP et al. Genome organization of epidemic Acinetobacter baumannii strains. 2011 BMC Microbiol. pmid:21985032
Lv YK et al. Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-yttriate(III)] trihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21836844
Cheng D et al. A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. 2011 Curr Radiopharm pmid:22191610
Lv YK et al. Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-samarate(III)] trihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21836843
Toyokuni S Mysterious link between iron overload and CDKN2A/2B. 2011 J Clin Biochem Nutr pmid:21297911
Lawrence MC et al. Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cells. 2011 J. Biol. Chem. pmid:21059644
Kolodziejczyk J et al. In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. 2011 J. Physiol. Biochem. pmid:21086198
Vu'o'ng Lê B et al. New rat models of iron sucrose-induced iron overload. 2011 Exp. Biol. Med. (Maywood) pmid:21685238
Kowalczyk MC et al. Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors. 2011 Oncol. Rep. pmid:21687956
Evstatiev R et al. FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease. 2011 Gastroenterology pmid:21699794
Solak Y et al. Comparison of adverse-event profiles of intravenous low-molecular-weight iron dextran and iron sucrose in peritoneal dialysis patients. 2011 Ren Fail pmid:21401355
Gambini JP et al. Evaluation of 99mTc-glucarate as a breast cancer imaging agent in a xenograft animal model. 2011 Nucl. Med. Biol. pmid:21315281
Takeda Y et al. Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients. 2011 Am. J. Nephrol. pmid:21502756
Meier T et al. Physicochemical and toxicological characterization of a new generic iron sucrose preparation. 2011 Arzneimittelforschung pmid:21428246
Agarwal R et al. Proteinuria induced by parenteral iron in chronic kidney disease--a comparative randomized controlled trial. 2011 Clin J Am Soc Nephrol pmid:20876669
Auerbach M Should intravenous iron be upfront therapy for iron deficiency anemia? 2011 Pediatr Blood Cancer pmid:21298731
Krafft A and Breymann C Iron sucrose with and without recombinant erythropoietin for the treatment of severe postpartum anemia: a prospective, randomized, open-label study. 2011 J. Obstet. Gynaecol. Res. pmid:21159035
Stefánsson BV et al. Acute oxidative stress following intravenous iron injection in patients on chronic hemodialysis: a comparison of iron-sucrose and iron-dextran. 2011 Nephron Clin Pract pmid:21196770
Atalay H et al. Safety profiles of total dose infusion of low-molecular-weight iron dextran and high-dose iron sucrose in renal patients. 2011 Hemodial Int pmid:21564503
Serrano-Trenas JA et al. Role of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial. 2011 Transfusion pmid:20630042
Malovrh M et al. The influence of need-based, continuous, low-dose iron replacement on hemoglobin levels in hemodialysis patients treated with erythropoiesis-stimulating agents. 2011 Artif Organs pmid:20618233
Rottembourg J et al. Do two intravenous iron sucrose preparations have the same efficacy? 2011 Nephrol. Dial. Transplant. pmid:21355067
Kim Y et al. Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. 2011 Nutr Res pmid:22118754
Bailie GR et al. Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. 2011 Arzneimittelforschung pmid:21755809
Gomollón F and Gisbert JP IBD: Intravenous iron in IBD--what's the best preparation? 2011 Nat Rev Gastroenterol Hepatol pmid:21788975
Bisbe E et al. A multicentre comparative study on the efficacy of intravenous ferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery. 2011 Br J Anaesth pmid:21841061
Toblli JE et al. Assessment of the extent of oxidative stress induced by intravenous ferumoxytol, ferric carboxymaltose, iron sucrose and iron dextran in a nonclinical model. 2011 Arzneimittelforschung pmid:21899208
Goggin MM et al. Analysis of total and transferrin-bound iron in human serum for pharmacokinetic studies of iron-sucrose formulations. 2011 Bioanalysis pmid:21877893
Ruiz JC et al. Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. 2011 PLoS ONE pmid:21533164
Yetman AT and Everitt MD The role of iron deficiency in protein-losing enteropathy following the Fontan procedure. 2011 Jul-Aug Congenit Heart Dis pmid:21392262
Adhikary L and Acharya S Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. 2011 Jul-Sep JNMA J Nepal Med Assoc pmid:22922860
Moorani KN and Asim S Parenteral iron sucrose in iron deficiency anaemia of paediatric chronic kidney disease. 2011 Jul-Sep J Ayub Med Coll Abbottabad pmid:23272434
Kowalczyk M et al. Ferumoxytol: a new era of iron deficiency anemia treatment for patients with chronic kidney disease. 2011 Nov-Dec J. Nephrol. pmid:21956770
Bhattacharya S et al. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. 2011 Nov-Dec J. Biochem. Mol. Toxicol. pmid:21538728
Sricholpech M et al. Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. 2012 J. Biol. Chem. pmid:22573318
Wyffels L et al. Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate. 2012 Mol Imaging pmid:22554483
Smith AA et al. The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. 2012 PLoS Comput. Biol. pmid:22693442
De Sousa A and Kalra G Drug therapy of attention deficit hyperactivity disorder: current trends. 2012 Mens Sana Monogr pmid:22654382
Ceretta LB et al. Increased oxidative stress and imbalance in antioxidant enzymes in the brains of alloxan-induced diabetic rats. 2012 Exp Diabetes Res pmid:22645603
Pfenniger A et al. Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. 2012 J Perinat Med pmid:22752771
da Silva Krause M et al. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. 2012 J. Endocrinol. pmid:22761278
Galindo P et al. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. 2012 PLoS ONE pmid:22427863
Conner TA et al. Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. 2012 Biometals pmid:22706571