Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Grzegorzewska AE | [Administration of iron-containing drugs in non-dialyzed patients with chronic kidney disease]. | 2007 | Pol. Arch. Med. Wewn. | pmid:17722476 |
Drzewiecki J | Excretion of D-glucaric acid and metabolism of salicylamide in man: the effect of phenobarbital-produced enzymatic induction. | 1977 Jul-Aug | Pol J Pharmacol Pharm | pmid:905203 |
Horváth T et al. | Investigation of biotransformation capacity in patients with chronic liver diseases by pharmacokinetic methods: experimental trials. | 1984 Jul-Aug | Pol J Pharmacol Pharm | pmid:6396596 |
Chaudhuri RR et al. | Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. | 2010 | PLoS ONE | pmid:20098708 |
Bidossi A et al. | A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. | 2012 | PLoS ONE | pmid:22428019 |
Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
Barbieri C et al. | Performance of a Predictive Model for Long-Term Hemoglobin Response to Darbepoetin and Iron Administration in a Large Cohort of Hemodialysis Patients. | 2016 | PLoS ONE | pmid:26939055 |
Connor JR et al. | Comparative evaluation of nephrotoxicity and management by macrophages of intravenous pharmaceutical iron formulations. | 2015 | PLoS ONE | pmid:25973894 |
Italia K et al. | Hydroxyurea could be a good clinically relevant iron chelator. | 2013 | PLoS ONE | pmid:24349400 |
Ruiz JC et al. | Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. | 2011 | PLoS ONE | pmid:21533164 |