Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Brunelle FM and Verbeeck RK | Glucuronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity. | 1993 | Biochem. Pharmacol. | pmid:8267644 |
Hoffmann D | [Role of phagocytosis and soluble antibacterial factors in experimental immunization of Locusta migratoria]. | 1976 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:821627 |
Marselos M | Genetic variation of drug-metabolizing enzymes in the wistar rat. | 1976 | Acta Pharmacol Toxicol (Copenh) | pmid:821309 |
Curley RW et al. | Activity of D-glucarate analogues: synergistic antiproliferative effects with retinoid in cultured human mammary tumor cells appear to specifically require the D-glucarate structure. | 1994 | Life Sci. | pmid:8190001 |
Webb TE et al. | Pharmacokinetics relevant to the anti-carcinogenic and anti-tumor activities of glucarate and the synergistic combination of glucarate:retinoid in the rat. | 1994 | Biochem. Pharmacol. | pmid:8185680 |
Newman MA et al. | Urinary biological monitoring markers of anticancer drug exposure in oncology nurses. | 1994 | Am J Public Health | pmid:8179062 |
Ferreira M et al. | Determinants of urinary thioethers, D-glucaric acid and mutagenicity after exposure to polycyclic aromatic hydrocarbons assessed by air monitoring and measurement of 1-hydroxypyrene in urine: a cross-sectional study in workers of coke and graphite-electrode-producing plants. | 1994 | Int Arch Occup Environ Health | pmid:8175189 |
Franco G and Fonte R | Advances in evaluating liver response to operating theatre work: urinary D-glucaric acid as an index of effect. | 1994 | Occup Med (Lond) | pmid:8167312 |
Marselos M and Laitinen M | Starvation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa. | 1975 | Biochem. Pharmacol. | pmid:811226 |
Marselos M et al. | Aldehyde dehydrogenase inducibility and ethanol preference in rats. | 1975 | Med. Biol. | pmid:810629 |