Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sricholpech M et al. | Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. | 2012 | J. Biol. Chem. | pmid:22573318 |
Wyffels L et al. | Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate. | 2012 | Mol Imaging | pmid:22554483 |
Monsénégo J et al. | Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. | 2012 | J. Hepatol. | pmid:22037024 |
Ozkurt S et al. | Acute and subacute effects of EV iron sucrose on endothelial functions in hemodialysis patients. | 2012 | Ren Fail | pmid:22017464 |
Toblli JE et al. | Comparison of oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model. | 2012 | Inflamm Allergy Drug Targets | pmid:22309085 |
Stachowska-Pietka J et al. | Computer simulations of osmotic ultrafiltration and small-solute transport in peritoneal dialysis: a spatially distributed approach. | 2012 | Am. J. Physiol. Renal Physiol. | pmid:22301624 |
Smith AA et al. | The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. | 2012 | PLoS Comput. Biol. | pmid:22693442 |
De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
Ceretta LB et al. | Increased oxidative stress and imbalance in antioxidant enzymes in the brains of alloxan-induced diabetic rats. | 2012 | Exp Diabetes Res | pmid:22645603 |
Bidossi A et al. | A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. | 2012 | PLoS ONE | pmid:22428019 |
Galutira PJ and Del Rio M | Understanding renal posttransplantation anemia in the pediatric population. | 2012 | Pediatr. Nephrol. | pmid:22086345 |
Rashid K et al. | Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. | 2012 | Free Radic. Res. | pmid:22239106 |
Ichii H et al. | Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. | 2012 | Am. J. Nephrol. | pmid:22722756 |
Pfenniger A et al. | Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. | 2012 | J Perinat Med | pmid:22752771 |
da Silva Krause M et al. | Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. | 2012 | J. Endocrinol. | pmid:22761278 |
Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
Conner TA et al. | Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. | 2012 | Biometals | pmid:22706571 |
Walters KR et al. | Methamphetamine causes anorexia in Drosophila melanogaster, exhausting metabolic reserves and contributing to mortality. | 2012 | J Toxicol Sci | pmid:22863857 |
Bespalov VG and Aleksandrov VA | [Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors]. | 2012 | Vopr Onkol | pmid:23607211 |
Xia B et al. | A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. | 2012 | Mol. Pharm. | pmid:23033922 |
Kowalczyk M et al. | Ferumoxytol: a new era of iron deficiency anemia treatment for patients with chronic kidney disease. | 2011 Nov-Dec | J. Nephrol. | pmid:21956770 |
Bhattacharya S et al. | Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. | 2011 Nov-Dec | J. Biochem. Mol. Toxicol. | pmid:21538728 |
Adhikary L and Acharya S | Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. | 2011 Jul-Sep | JNMA J Nepal Med Assoc | pmid:22922860 |
Moorani KN and Asim S | Parenteral iron sucrose in iron deficiency anaemia of paediatric chronic kidney disease. | 2011 Jul-Sep | J Ayub Med Coll Abbottabad | pmid:23272434 |
Yetman AT and Everitt MD | The role of iron deficiency in protein-losing enteropathy following the Fontan procedure. | 2011 Jul-Aug | Congenit Heart Dis | pmid:21392262 |
Centeno DC et al. | Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. | 2011 | Plant Cell | pmid:21239646 |
Toblli JE et al. | Evaluation of toxicity and oxidative stress induced by intravenous iron isomaltoside 1000 in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:22164963 |
Menendez C et al. | Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed? | 2011 | Mol Nutr Food Res | pmid:22144045 |
Cheng D et al. | A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. | 2011 | Curr Radiopharm | pmid:22191610 |
Toyokuni S | Mysterious link between iron overload and CDKN2A/2B. | 2011 | J Clin Biochem Nutr | pmid:21297911 |
Lawrence MC et al. | Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cells. | 2011 | J. Biol. Chem. | pmid:21059644 |
Kolodziejczyk J et al. | In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. | 2011 | J. Physiol. Biochem. | pmid:21086198 |
Vu'o'ng Lê B et al. | New rat models of iron sucrose-induced iron overload. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21685238 |
Kowalczyk MC et al. | Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors. | 2011 | Oncol. Rep. | pmid:21687956 |
Evstatiev R et al. | FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease. | 2011 | Gastroenterology | pmid:21699794 |
Solak Y et al. | Comparison of adverse-event profiles of intravenous low-molecular-weight iron dextran and iron sucrose in peritoneal dialysis patients. | 2011 | Ren Fail | pmid:21401355 |
Gambini JP et al. | Evaluation of 99mTc-glucarate as a breast cancer imaging agent in a xenograft animal model. | 2011 | Nucl. Med. Biol. | pmid:21315281 |
Takeda Y et al. | Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients. | 2011 | Am. J. Nephrol. | pmid:21502756 |
Meier T et al. | Physicochemical and toxicological characterization of a new generic iron sucrose preparation. | 2011 | Arzneimittelforschung | pmid:21428246 |
Agarwal R et al. | Proteinuria induced by parenteral iron in chronic kidney disease--a comparative randomized controlled trial. | 2011 | Clin J Am Soc Nephrol | pmid:20876669 |
Auerbach M | Should intravenous iron be upfront therapy for iron deficiency anemia? | 2011 | Pediatr Blood Cancer | pmid:21298731 |
Crary SE et al. | Intravenous iron sucrose for children with iron deficiency failing to respond to oral iron therapy. | 2011 | Pediatr Blood Cancer | pmid:21298748 |
Ibert M et al. | Evidence of benzilic rearrangement during the electrochemical oxidation of D-glucose to D-glucaric acid. | 2011 | Carbohydr. Res. | pmid:21269605 |
Serrano-Trenas JA et al. | Role of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial. | 2011 | Transfusion | pmid:20630042 |
Malovrh M et al. | The influence of need-based, continuous, low-dose iron replacement on hemoglobin levels in hemodialysis patients treated with erythropoiesis-stimulating agents. | 2011 | Artif Organs | pmid:20618233 |
Bailie GR et al. | Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. | 2011 | Arzneimittelforschung | pmid:21755809 |
Gomollón F and Gisbert JP | IBD: Intravenous iron in IBD--what's the best preparation? | 2011 | Nat Rev Gastroenterol Hepatol | pmid:21788975 |
Bisbe E et al. | A multicentre comparative study on the efficacy of intravenous ferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery. | 2011 | Br J Anaesth | pmid:21841061 |
Toblli JE et al. | Assessment of the extent of oxidative stress induced by intravenous ferumoxytol, ferric carboxymaltose, iron sucrose and iron dextran in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:21899208 |
Goggin MM et al. | Analysis of total and transferrin-bound iron in human serum for pharmacokinetic studies of iron-sucrose formulations. | 2011 | Bioanalysis | pmid:21877893 |