Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Addison Disease D000224 3 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alcoholism D000437 27 associated lipids
Anemia D000740 21 associated lipids
Anemia, Neonatal D000751 1 associated lipids
Anemia, Refractory D000753 3 associated lipids
Arthritis, Rheumatoid D001172 3 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Biliary Tract Diseases D001660 3 associated lipids
Body Weight D001835 333 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Carbon Tetrachloride Poisoning D002252 12 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Brain Ischemia D002545 89 associated lipids
Dehydration D003681 11 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Edema D004487 152 associated lipids
Epilepsy D004827 35 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Fasciitis D005208 2 associated lipids
Femoral Neck Fractures D005265 3 associated lipids
Gilbert Disease D005878 2 associated lipids
Glucosephosphate Dehydrogenase Deficiency D005955 5 associated lipids
Hearing Disorders D006311 10 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heart Failure D006333 36 associated lipids
Hemolysis D006461 131 associated lipids
Hemosiderosis D006486 1 associated lipids
Hepatitis D006505 11 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperbilirubinemia, Hereditary D006933 3 associated lipids
Hypercalcemia D006934 13 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperplasia D006965 34 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypocalcemia D006996 12 associated lipids
Hypotension D007022 41 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Leprosy D007918 8 associated lipids
Leukemia P388 D007941 43 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Lung Neoplasms D008175 171 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Myocardial Infarction D009203 21 associated lipids
Occupational Diseases D009784 42 associated lipids
Osteomalacia D010018 5 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease D010300 53 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
Precancerous Conditions D011230 48 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
Testicular Neoplasms D013736 5 associated lipids
Thrombophlebitis D013924 6 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
von Willebrand Diseases D014842 2 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Blood Loss, Surgical D016063 6 associated lipids
Critical Illness D016638 13 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Myocardial Stunning D017682 10 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Iron Overload D019190 11 associated lipids
Neurocysticercosis D020019 1 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Atherosclerosis D050197 85 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Carcinogenesis D063646 3 associated lipids
Rickets, Hypophosphatemic D063730 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Per page 10 20 50 100 | Total 1061
Authors Title Published Journal PubMed Link
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Gehret TC et al. Convenient large-scale synthesis of D-glucaro-1,4:6,3-dilactone. 2009 J. Org. Chem. pmid:19777999
Edwards TJ et al. Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery. 2009 Br J Surg pmid:19731228
Yoon SH et al. Cloning and characterization of uronate dehydrogenases from two pseudomonads and Agrobacterium tumefaciens strain C58. 2009 J. Bacteriol. pmid:19060141
Moon TS et al. Production of glucaric acid from a synthetic pathway in recombinant Escherichia coli. 2009 Appl. Environ. Microbiol. pmid:19060162
Luo Z et al. Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells. 2009 Endocrine pmid:19440859
Grote L et al. A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome. 2009 Mov. Disord. pmid:19489063
Kulnigg S et al. Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment. 2009 Am. J. Gastroenterol. pmid:19491860
Krafft A et al. Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone. 2009 Fetal. Diagn. Ther. pmid:19506383
Asma S et al. Safety, therapeutic effectiveness, and cost of parenteral iron therapy. 2009 Int. J. Hematol. pmid:19495930
García-Erce JA et al. Efficacy of preoperative recombinant human erythropoietin administration for reducing transfusion requirements in patients undergoing surgery for hip fracture repair. An observational cohort study. 2009 Vox Sang. pmid:19497085
Nguyen TV Comparison of serum ferritin and transferrin saturation values associated with two i.v. iron formulations in hemodialysis patients. 2009 Am J Health Syst Pharm pmid:19498125
Fontés G et al. Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. 2009 Diabetes pmid:19502418
Shimizu Y et al. Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. 2009 Bone pmid:19555782
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Dueber JE et al. Synthetic protein scaffolds provide modular control over metabolic flux. 2009 Nat. Biotechnol. pmid:19648908
Lindgren S et al. Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluator-blind, multicentre study. 2009 Scand. J. Gastroenterol. pmid:19330567
Comín-Colet J et al. A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: influence on neurohormonal activation and clinical outcomes. 2009 J. Card. Fail. pmid:19879457
Morimoto S et al. Significance of urinary glucaric acid measurement and its application to paclitaxel therapy. 2009 Gan To Kagaku Ryoho pmid:19920388
Gambini JP et al. Evaluation of patients with head and neck cancer by means of 99mTc-glucarate. 2009 J Nucl Med Technol pmid:19949020
Smith TG et al. Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials. 2009 JAMA pmid:19809026
Muñoz M et al. Intravenous iron in inflammatory bowel disease. 2009 World J. Gastroenterol. pmid:19787830
Zanor MI et al. Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. 2009 J. Exp. Bot. pmid:19346240
Gredilla E et al. [Treating severe acute anemia due to vaginal bleeding in the Jehovah's Witness: a report of 2 cases]. 2009 Rev Esp Anestesiol Reanim pmid:20151526
Earley CJ et al. A randomized, double-blind, placebo-controlled trial of intravenous iron sucrose in restless legs syndrome. 2009 Sleep Med. pmid:18280205