Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Yoon J et al. | Postoperative high-dose intravenous iron sucrose with low dose erythropoietin therapy after total hip replacement. | 2010 | Korean J. Intern. Med. | pmid:21179286 |
Moon TS et al. | Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli. | 2010 | Metab. Eng. | pmid:20117231 |
Li LO et al. | Early hepatic insulin resistance in mice: a metabolomics analysis. | 2010 | Mol. Endocrinol. | pmid:20150186 |
Simpson JA et al. | Letter 2: Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery (Br J Surg 2009; 96: 1122-1128). | 2010 | Br J Surg | pmid:20069594 |
Ranganathan P and Pramesh CS | Letter 1: Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery (Br J Surg 2009; 96: 1122-1128). | 2010 | Br J Surg | pmid:20069595 |
Kowalczyk MC et al. | Synergistic effects of combined phytochemicals and skin cancer prevention in SENCAR mice. | 2010 | Cancer Prev Res (Phila) | pmid:20103723 |
Hu Q et al. | Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. | 2010 | Lab. Invest. | pmid:20065947 |
Hedenus M and Birgegård G | The role of iron supplementation during epoietin treatment for cancer-related anemia. | 2009 | Med. Oncol. | pmid:18473194 |
Costa S et al. | In vitro evaluation of the chemoprotective action mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenol-induced cell damage. | 2009 | J Appl Toxicol | pmid:18636399 |
Kell DB | Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. | 2009 | BMC Med Genomics | pmid:19133145 |
PERSOONIAL Reflections. | 2009 | Persoonia | pmid:20198167 | |
Ginsberg G and Rice DC | Does rapid metabolism ensure negligible risk from bisphenol A? | 2009 | Environ. Health Perspect. | pmid:20049111 |
Fior S and Gerola PD | Impact of ubiquitous inhibitors on the GUS gene reporter system: evidence from the model plants Arabidopsis, tobacco and rice and correction methods for quantitative assays of transgenic and endogenous GUS. | 2009 | Plant Methods | pmid:20042078 |
Dong T and Schellhorn HE | Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933. | 2009 | BMC Genomics | pmid:19650909 |
Barraclough KA et al. | Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial). | 2009 | BMC Nephrol | pmid:19635169 |
Haddad A et al. | Use of iron sucrose in dialysis patients sensitive to iron dextran. | 2009 | Saudi J Kidney Dis Transpl | pmid:19237805 |
Pollak VE et al. | The importance of iron in long-term survival of maintenance hemodialysis patients treated with epoetin-alfa and intravenous iron: analysis of 9.5 years of prospectively collected data. | 2009 | BMC Nephrol | pmid:19245700 |
Torres-Corzo JG et al. | Comparison of cerebrospinal fluid obtained by ventricular endoscopy and by lumbar puncture in patients with hydrocephalus secondary to neurocysticercosis. | 2009 | Surg Neurol | pmid:19249584 |
Clark SF | Iron deficiency anemia: diagnosis and management. | 2009 | Curr. Opin. Gastroenterol. | pmid:19262200 |
Muñoz M et al. | [Usefulness of the administration of intravenous iron sucrose for the correction of preoperative anemia in major surgery patients]. | 2009 | Med Clin (Barc) | pmid:19264195 |
Breborowicz A et al. | Intravenous iron sucrose changes the intraperitoneal homeostasis. | 2009 | Blood Purif. | pmid:19325240 |
Gorder V et al. | Treatment of restless legs syndrome with iron infusion therapy. | 2009 | JAAPA | pmid:19354112 |
De Saint-Hubert M et al. | Molecular imaging of cell death. | 2009 | Methods | pmid:19362149 |
Kim YH et al. | Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study. | 2009 | Acta Haematol. | pmid:19332985 |
Gehret TC et al. | Convenient large-scale synthesis of D-glucaro-1,4:6,3-dilactone. | 2009 | J. Org. Chem. | pmid:19777999 |
Edwards TJ et al. | Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery. | 2009 | Br J Surg | pmid:19731228 |
Yoon SH et al. | Cloning and characterization of uronate dehydrogenases from two pseudomonads and Agrobacterium tumefaciens strain C58. | 2009 | J. Bacteriol. | pmid:19060141 |
Moon TS et al. | Production of glucaric acid from a synthetic pathway in recombinant Escherichia coli. | 2009 | Appl. Environ. Microbiol. | pmid:19060162 |
Luo Z et al. | Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells. | 2009 | Endocrine | pmid:19440859 |
Grote L et al. | A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome. | 2009 | Mov. Disord. | pmid:19489063 |
Kulnigg S et al. | Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment. | 2009 | Am. J. Gastroenterol. | pmid:19491860 |
Krafft A et al. | Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone. | 2009 | Fetal. Diagn. Ther. | pmid:19506383 |
Asma S et al. | Safety, therapeutic effectiveness, and cost of parenteral iron therapy. | 2009 | Int. J. Hematol. | pmid:19495930 |
GarcÃa-Erce JA et al. | Efficacy of preoperative recombinant human erythropoietin administration for reducing transfusion requirements in patients undergoing surgery for hip fracture repair. An observational cohort study. | 2009 | Vox Sang. | pmid:19497085 |
Nguyen TV | Comparison of serum ferritin and transferrin saturation values associated with two i.v. iron formulations in hemodialysis patients. | 2009 | Am J Health Syst Pharm | pmid:19498125 |
Fontés G et al. | Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. | 2009 | Diabetes | pmid:19502418 |
Shimizu Y et al. | Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. | 2009 | Bone | pmid:19555782 |
Li H and Wang SX | [Intravenous iron sucrose in maintenance dialysis patients with renal anemia: a clinical study]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:19567093 |
Toblli JE et al. | Differences between original intravenous iron sucrose and iron sucrose similar preparations. | 2009 | Arzneimittelforschung | pmid:19517894 |
Yi CX et al. | A major role for perifornical orexin neurons in the control of glucose metabolism in rats. | 2009 | Diabetes | pmid:19592616 |
Dueber JE et al. | Synthetic protein scaffolds provide modular control over metabolic flux. | 2009 | Nat. Biotechnol. | pmid:19648908 |
Lindgren S et al. | Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluator-blind, multicentre study. | 2009 | Scand. J. Gastroenterol. | pmid:19330567 |
ComÃn-Colet J et al. | A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: influence on neurohormonal activation and clinical outcomes. | 2009 | J. Card. Fail. | pmid:19879457 |
Morimoto S et al. | Significance of urinary glucaric acid measurement and its application to paclitaxel therapy. | 2009 | Gan To Kagaku Ryoho | pmid:19920388 |
Gambini JP et al. | Evaluation of patients with head and neck cancer by means of 99mTc-glucarate. | 2009 | J Nucl Med Technol | pmid:19949020 |
Smith TG et al. | Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials. | 2009 | JAMA | pmid:19809026 |
Muñoz M et al. | Intravenous iron in inflammatory bowel disease. | 2009 | World J. Gastroenterol. | pmid:19787830 |
Zanor MI et al. | Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. | 2009 | J. Exp. Bot. | pmid:19346240 |
Gredilla E et al. | [Treating severe acute anemia due to vaginal bleeding in the Jehovah's Witness: a report of 2 cases]. | 2009 | Rev Esp Anestesiol Reanim | pmid:20151526 |
Earley CJ et al. | A randomized, double-blind, placebo-controlled trial of intravenous iron sucrose in restless legs syndrome. | 2009 | Sleep Med. | pmid:18280205 |