Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Centeno DC et al. | Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. | 2011 | Plant Cell | pmid:21239646 |
Walther J et al. | Hot transcriptomics. | 2011 | Archaea | pmid:21350598 |
Bhattacharya S et al. | D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21982801 |
Di Nocera PP et al. | Genome organization of epidemic Acinetobacter baumannii strains. | 2011 | BMC Microbiol. | pmid:21985032 |
Lv YK et al. | Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-yttriate(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836844 |
Lv YK et al. | Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-samarate(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836843 |
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Lawrence MC et al. | Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cells. | 2011 | J. Biol. Chem. | pmid:21059644 |
Kolodziejczyk J et al. | In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. | 2011 | J. Physiol. Biochem. | pmid:21086198 |
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Rottembourg J et al. | Do two intravenous iron sucrose preparations have the same efficacy? | 2011 | Nephrol. Dial. Transplant. | pmid:21355067 |
Kim Y et al. | Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. | 2011 | Nutr Res | pmid:22118754 |
Bailie GR et al. | Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. | 2011 | Arzneimittelforschung | pmid:21755809 |
Gomollón F and Gisbert JP | IBD: Intravenous iron in IBD--what's the best preparation? | 2011 | Nat Rev Gastroenterol Hepatol | pmid:21788975 |
Bisbe E et al. | A multicentre comparative study on the efficacy of intravenous ferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery. | 2011 | Br J Anaesth | pmid:21841061 |
Toblli JE et al. | Assessment of the extent of oxidative stress induced by intravenous ferumoxytol, ferric carboxymaltose, iron sucrose and iron dextran in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:21899208 |
Goggin MM et al. | Analysis of total and transferrin-bound iron in human serum for pharmacokinetic studies of iron-sucrose formulations. | 2011 | Bioanalysis | pmid:21877893 |
Ruiz JC et al. | Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. | 2011 | PLoS ONE | pmid:21533164 |
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Chaudhuri RR et al. | Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. | 2010 | PLoS ONE | pmid:20098708 |
Suzuki E et al. | Identification of valproic acid glucuronide hydrolase as a key enzyme for the interaction of valproic acid with carbapenem antibiotics. | 2010 | Drug Metab. Dispos. | pmid:20551238 |
Hoffman K et al. | Exposure to polyfluoroalkyl chemicals and attention deficit/hyperactivity disorder in U.S. children 12-15 years of age. | 2010 | Environ. Health Perspect. | pmid:20551004 |
Sienkiewicz-Porzucek A et al. | Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth. | 2010 | Mol Plant | pmid:20035036 |
Sturm B et al. | In vitro study on the effects of iron sucrose, ferric gluconate and iron dextran on redox-active iron and oxidative stress. | 2010 | Arzneimittelforschung | pmid:20712137 |
Swarnalatha G et al. | Oxidative stress in hemodialysis patients receiving intravenous iron therapy and the role of N-acetylcysteine in preventing oxidative stress. | 2010 | Saudi J Kidney Dis Transpl | pmid:20814119 |
Froessler B and Papendorf D | Intravenous iron sucrose--an effective and attractive modality for perioperative anaemia management. | 2010 | Anaesth Intensive Care | pmid:20865896 |
Saluk-Juszczak J | A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. | 2010 | Platelets | pmid:20873960 |
Yoon J et al. | Postoperative high-dose intravenous iron sucrose with low dose erythropoietin therapy after total hip replacement. | 2010 | Korean J. Intern. Med. | pmid:21179286 |
Dangsuwan P and Manchana T | Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy. | 2010 | Gynecol. Oncol. | pmid:20051288 |
Lajolo C et al. | Calcium glucarate inhibits DMBA-induced oral carcinogenesis in the hamster: histomorphometric evaluation. | 2010 | Anticancer Res. | pmid:20393005 |
Wu CJ et al. | Comparison of parenteral iron sucrose and ferric chloride during erythropoietin therapy of haemodialysis patients. | 2010 | Nephrology (Carlton) | pmid:20377770 |
McMahon LP et al. | Maintenance of elevated versus physiological iron indices in non-anaemic patients with chronic kidney disease: a randomized controlled trial. | 2010 | Nephrol. Dial. Transplant. | pmid:19906658 |
Rombouts K and Marra F | Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis. | 2010 | Dig Dis | pmid:20460917 |
Rangel EB et al. | Labile plasma iron generation after intravenous iron is time-dependent and transitory in patients undergoing chronic hemodialysis. | 2010 | Ther Apher Dial | pmid:20438541 |
Tampi R | Delayed adverse reactions to iron polymaltose and iron sucrose. | 2010 | Intern Med J | pmid:20446963 |
Garcia-Fernandez N et al. | Randomized clinical trial on acute effects of i.v. iron sucrose during haemodialysis. | 2010 | Nephrology (Carlton) | pmid:20470276 |
Firoz BF et al. | Eosinophilic fasciitis secondary to intravenous iron infusions. | 2010 | Dermatol. Online J. | pmid:20492822 |
Gupta A et al. | Response to iron sucrose in dialysis patients sensitive to iron dextran. | 2010 | Saudi J Kidney Dis Transpl | pmid:20587886 |
Zhang ZW et al. | The plastid hexokinase pHXK: a node of convergence for sugar and plastid signals in Arabidopsis. | 2010 | FEBS Lett. | pmid:20650273 |
Okada DR et al. | 99mTc-glucarate kinetics differentiate normal, stunned, hibernating, and nonviable myocardium in a perfused rat heart model. | 2010 | Eur. J. Nucl. Med. Mol. Imaging | pmid:20652807 |
Chinnappa S and Bhandari S | Influence of intravenous iron therapy on novel markers of iron deficiency. | 2010 | Int J Artif Organs | pmid:20593351 |
Birgegård G et al. | High incidence of iron depletion and restless leg syndrome (RLS) in regular blood donors: intravenous iron sucrose substitution more effective than oral iron. | 2010 | Vox Sang. | pmid:20598107 |
Johnson AC et al. | Parenteral iron formulations differentially affect MCP-1, HO-1, and NGAL gene expression and renal responses to injury. | 2010 | Am. J. Physiol. Renal Physiol. | pmid:20504881 |
Fernández-Gallego J et al. | [Treatment with intravenous iron and ferritin level]. | 2010 | Nefrologia | pmid:20514109 |
Moon TS et al. | Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli. | 2010 | Metab. Eng. | pmid:20117231 |
Li LO et al. | Early hepatic insulin resistance in mice: a metabolomics analysis. | 2010 | Mol. Endocrinol. | pmid:20150186 |
Simpson JA et al. | Letter 2: Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery (Br J Surg 2009; 96: 1122-1128). | 2010 | Br J Surg | pmid:20069594 |
Ranganathan P and Pramesh CS | Letter 1: Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery (Br J Surg 2009; 96: 1122-1128). | 2010 | Br J Surg | pmid:20069595 |
Kowalczyk MC et al. | Synergistic effects of combined phytochemicals and skin cancer prevention in SENCAR mice. | 2010 | Cancer Prev Res (Phila) | pmid:20103723 |
Hu Q et al. | Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. | 2010 | Lab. Invest. | pmid:20065947 |