Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Smith AA et al. | The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. | 2012 | PLoS Comput. Biol. | pmid:22693442 |
Kamanna VS et al. | Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. | 2012 | Am. J. Nephrol. | pmid:22212390 |
Stein J et al. | Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. | 2012 | Curr Med Res Opin | pmid:22181342 |
Rashid K et al. | Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. | 2012 | Free Radic. Res. | pmid:22239106 |
Ichii H et al. | Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. | 2012 | Am. J. Nephrol. | pmid:22722756 |
Pfenniger A et al. | Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. | 2012 | J Perinat Med | pmid:22752771 |
da Silva Krause M et al. | Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. | 2012 | J. Endocrinol. | pmid:22761278 |
Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
Isnardi V et al. | Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? | 2012 | Nucl. Med. Biol. | pmid:23084044 |
Xia B et al. | A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. | 2012 | Mol. Pharm. | pmid:23033922 |