Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Horváth T et al. | Correlation between biochemical tests, parameters of drug elimination and hepatic enzyme induction in chronic liver diseases. | 1983 | Acta Med Hung | pmid:6674914 |
Vezekenyi Z et al. | Human tolerance of flumecinol (Zixoryn, RGH-3332), its regime and dosage in healthy volunteers. | 1983 | Int J Clin Pharmacol Res | pmid:6679516 |
Gachályi B et al. | m-Trifluoromethyl-alpha-ethylbenzhydrol: a new enzyme inducer. | 1978 | Eur. J. Clin. Pharmacol. | pmid:668788 |
Freundt KJ | Variable inhibition of human hepatic drug metabolizing enzymes by disulfiram. | 1978 | Int J Clin Pharmacol Biopharm | pmid:669879 |
Nakajima M et al. | Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase. | 1984 | J. Biol. Chem. | pmid:6698965 |
Loi AM et al. | [Urinary secretion of D-glucaric acid in subjects exposed to styrene]. | 1984 Mar-Apr | Med Lav | pmid:6749047 |
Gargan R et al. | A concise biotyping system for differentiating strains of Escherichia coli. | 1982 | J. Clin. Pathol. | pmid:6757274 |
Németh I et al. | Hyperbilirubinemia and urinary D-glucaric acid excretion in premature infants following antepartum dexamethasone treatment. | 1981 | J Perinat Med | pmid:6783743 |
Matsuoka S et al. | Correlation between the level of urinary D-glucaric acid and the degree of activation of masked compound (FT-207) in cancer patients. | 1981 | Tohoku J. Exp. Med. | pmid:6797104 |
Richens A et al. | Effects of sodium valproate on the serum protein binding of phenytoin, and on liver enzyme activity. | 1980 | Monogr Neural Sci | pmid:6798427 |
Ohnhaus EE et al. | The effect of antipyrine, phenobarbitol and rifampicin on thyroid hormone metabolism in man. | 1981 | Eur. J. Clin. Invest. | pmid:6800809 |
Tanaka H et al. | [A growth media of genus Legionella in containing saccharated ferric oxide (Fesin) replacing soluble ferric pyrophosphate (author's transl)]. | 1982 | Kansenshogaku Zasshi | pmid:6809855 |
Kriebel D et al. | Detection of occupational exposure to genotoxic agents with a urinary mutagen assay. | 1983 | Mutat. Res. | pmid:6835232 |
Okada M et al. | Hypophosphatemia induced by intravenous administration of Saccharated iron oxide. | 1983 | Klin. Wochenschr. | pmid:6843038 |
Colombi A et al. | Low-pH method for the enzymatic assay of D-glucaric acid in urine. | 1983 | Clin. Chim. Acta | pmid:6851142 |
Colombi A et al. | Influence of sex, age, and smoking habits on the urinary excretion of D-glucaric acid. | 1983 | Clin. Chim. Acta | pmid:6851143 |
Marselos M et al. | Responses of the D-glucuronic acid pathway in rat tissues to treatment with tetrachlorodibenzodioxin. | 1978 | Xenobiotica | pmid:685288 |
Layiwola PJ et al. | Hydrolysis of the biliary glucuronic acid conjugate of phenol by the intestinal mucus/flora of goldfish (Carassius auratus). | 1983 | Xenobiotica | pmid:6858197 |
Gachályi B et al. | Combined effect of alpha-methyldopa and a new enzyme inducer, Zixoryn, on the hepatic mixed-function monooxygenase system in humans. | 1983 | Int J Clin Pharmacol Ther Toxicol | pmid:6862721 |
Barot MH et al. | Individual variation in daily dosage requirements for phenytoin sodium in patients with epilepsy. | 1978 | Br J Clin Pharmacol | pmid:687505 |
Marre R et al. | Animal studies on the reduction of aminoglycoside-induced nephrotoxicity by D-glucaro-1,5-lactam. | 1983 May-Jun | Infection | pmid:6885175 |
Lai AA et al. | Time-course of interaction between carbamazepine and clonazepam in normal man. | 1978 | Clin. Pharmacol. Ther. | pmid:688725 |
Hartikka P et al. | Effect of iron-saccharin injections of Finnish horses. | 1983 May-Jun | Nord Vet Med | pmid:6889132 |
Bartels H et al. | [Relations between lipoprotein X and gamma glutamyltransferase in serum and D-saccharic acid in urine of mature, healthy newborn infants]. | 1976 | Monatsschr Kinderheilkd | pmid:6906 |
Micheletti C et al. | [Enzyme induction during treatment with isoniazid]. | 1978 Aug 26-Sep 2 | Nouv Presse Med | pmid:693296 |
Tesseromatis C et al. | Influence of liver enzyme induction caused by diphenylhydantoin and diazepam on bone mass of rats. | 1980 | Arch. Toxicol. Suppl. | pmid:6933970 |
Hotz P et al. | Study of some hepatic effects (induction and toxicity) caused by occupational exposure to styrene in the polyester industry. | 1980 | Scand J Work Environ Health | pmid:6937826 |
Keith DA et al. | Microsomal enzyme induction and gingival enlargement in subjects taking phenytoin. | 1981 | Arch. Oral Biol. | pmid:6951516 |
Budillon G et al. | Urinary excretion of D-glucaric acid, total glucuronic acid and total porphyrins in porphyria cutanea tarda. | 1978 | Acta Hepatogastroenterol (Stuttg) | pmid:696201 |
Herzberg M and Wiener MH | Increased D-glucaric acid excretion by jaundiced patients. | 1978 | Clin. Chem. | pmid:699285 |
Roberton AM et al. | Two genes affecting glucarate utilization in Escherichia coli K12. | 1980 | J. Gen. Microbiol. | pmid:6999115 |
Herd JK et al. | Synthesis of L-idaro-1,4-lactone, an inhibitor of alpha-L-idosiduronase. | 1982 | Carbohydr. Res. | pmid:7055824 |
Ideo G et al. | Increased urinary D-glucaric acid excretion by children living in an area polluted with tetrachlorodibenzoparadioxin (TCDD). | 1982 | Clin. Chim. Acta | pmid:7074964 |
Tanaka E et al. | Studies on the trimethadione metabolism as a tool for the assessment of drug-metabolizing capacity using plasma and urine of rats pretreated with phenobarbital and 3-methylcholanthrene. | 1982 | J. Pharmacobio-dyn. | pmid:7097483 |
Tanno Y and Takishima T | Enhancing effect of saccharated ferric oxide on human lymphocyte transformation in serum-free medium. | 1982 | Tohoku J. Exp. Med. | pmid:7101280 |
Lake BG et al. | The excretion of metabolites of the D-glucuronic acid pathway in human urine. Effect of phenobarbitone administration. | 1982 | Xenobiotica | pmid:7113260 |
Durlofsky L and Fruncillo RJ | Impaired drug-metabolizing ability in the burned rat. | 1982 | J Trauma | pmid:7143502 |
Okada M et al. | [2 cases of nonspecific multiple ulcers of the small intestine associated with osteomalacia caused by long-term intravenous administration of saccharated ferric oxide]. | 1982 | Nippon Naika Gakkai Zasshi | pmid:7166673 |
Horváth T et al. | Drug metabolism in alcoholic liver disease. | 1982 | Acta Med Acad Sci Hung | pmid:7185242 |
Chailleux E et al. | [Simultaneous study of the induction effect of rifampicin and the phenotype for acetylation of isoniazid in 21 patients with tuberculosis undergoing a combination treatment]. | 1980 | Rev Fr Mal Respir | pmid:7187065 |
Ho KJ and Ho LH | Determination of urinary beta-glucuronidase activity. Single-point versus enzyme kinetic measuring system. | 1980 | Enzyme | pmid:7202386 |
Németh I and Szeleczki T | Enhanced drug metabolism and renal dysfunction. | 1981 | Br J Clin Pharmacol | pmid:7213515 |
Marre R et al. | [Animal studies on ribostamycin (author's transl)]. | 1981 | Immun. Infekt. | pmid:7228116 |
Patel IH et al. | Induction effect of phenobarbital on the carbamazepine to carbamazepine-10, 11-epoxide pathway in rhesus monkeys. | 1981 | J. Pharmacol. Exp. Ther. | pmid:7229992 |
Jackson L et al. | The features of hepatic enzyme induction with glutethimide in man. | 1978 | Br J Clin Pharmacol | pmid:728322 |
Latham AN | Effect of data transformation on t-test sensitivity. | 1978 | Br J Clin Pharmacol | pmid:728324 |
Takemori N and Ito T | [Response of omental milk spots to colloidal saccharated ferric oxide in the mouse: light and electron microscopic study (author's transl)]. | 1981 | Hokkaido Igaku Zasshi | pmid:7327509 |
Affrime MB et al. | Failure of rifampin to induce the metabolism of clonidine in normal volunteers. | 1981 | Drug Intell Clin Pharm | pmid:7338192 |
Larousse C et al. | Tuberculosis therapy and enzyme induction in man. | 1980 | Int J Clin Pharmacol Ther Toxicol | pmid:7380590 |
Alsasua A et al. | [Urinary D-glucaric acid in portocaval shunt rats (author's transl)]. | 1980 | Arch Farmacol Toxicol | pmid:7387201 |