Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sricholpech M et al. | Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. | 2012 | J. Biol. Chem. | pmid:22573318 |
Wyffels L et al. | Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate. | 2012 | Mol Imaging | pmid:22554483 |
Muñoz M et al. | Effects of postoperative intravenous iron on transfusion requirements after lower limb arthroplasty. | 2012 | Br J Anaesth | pmid:22337966 |
Freburger JK et al. | Changing patterns of anemia management in US hemodialysis patients. | 2012 | Am. J. Med. | pmid:22938926 |
Christoph P et al. | Intravenous iron treatment in pregnancy: comparison of high-dose ferric carboxymaltose vs. iron sucrose. | 2012 | J Perinat Med | pmid:22945271 |
Rostoker G et al. | Hemodialysis-associated hemosiderosis in the era of erythropoiesis-stimulating agents: a MRI study. | 2012 | Am. J. Med. | pmid:22998881 |
Okam MM et al. | Comparative rates of adverse events with different formulations of intravenous iron. | 2012 | Am. J. Hematol. | pmid:22965928 |
Borchard G et al. | Nanoparticle iron medicinal products - Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies. | 2012 | Regul. Toxicol. Pharmacol. | pmid:22951348 |
Smith AA et al. | The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. | 2012 | PLoS Comput. Biol. | pmid:22693442 |
De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
Ceretta LB et al. | Increased oxidative stress and imbalance in antioxidant enzymes in the brains of alloxan-induced diabetic rats. | 2012 | Exp Diabetes Res | pmid:22645603 |
Yamamoto S et al. | Fibroblast growth factor 23-related osteomalacia caused by the prolonged administration of saccharated ferric oxide. | 2012 | Intern. Med. | pmid:22975552 |
Ernst MC et al. | Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. | 2012 | Endocrinology | pmid:22186410 |
Kamanna VS et al. | Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. | 2012 | Am. J. Nephrol. | pmid:22212390 |
Stein J et al. | Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. | 2012 | Curr Med Res Opin | pmid:22181342 |
Rashid K et al. | Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. | 2012 | Free Radic. Res. | pmid:22239106 |
Ichii H et al. | Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. | 2012 | Am. J. Nephrol. | pmid:22722756 |
Pfenniger A et al. | Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. | 2012 | J Perinat Med | pmid:22752771 |
da Silva Krause M et al. | Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. | 2012 | J. Endocrinol. | pmid:22761278 |
Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
Conner TA et al. | Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. | 2012 | Biometals | pmid:22706571 |
Araki T et al. | Clinical efficacy of two forms of intravenous iron--saccharated ferric oxide and cideferron--for iron deficiency anemia. | 2012 | Pharmazie | pmid:23346769 |
Isnardi V et al. | Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? | 2012 | Nucl. Med. Biol. | pmid:23084044 |
Xia B et al. | A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. | 2012 | Mol. Pharm. | pmid:23033922 |
Smith TN et al. | Modifications in the nitric acid oxidation of D-glucose. | 2012 | Carbohydr. Res. | pmid:22285512 |
Kumbasar A et al. | The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. | 2012 Sep-Oct | J. Nephrol. | pmid:22307439 |
Reinisch W et al. | State of the iron: how to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease. | 2013 | J Crohns Colitis | pmid:22917870 |
Basora M et al. | Optimizing preoperative haemoglobin with intravenous iron. | 2013 | Br J Anaesth | pmid:23404979 |
Yamamoto S et al. | Iatrogenic osteomalacia: report of two cases. | 2013 | J. UOEH | pmid:23475021 |
GarcÃa Erce JA et al. | [Thoughts about the usefulness of the preoperatory administration of intravenous iron in hip fracture surgery]. | 2013 | Med Clin (Barc) | pmid:23790583 |
Kowalczyk MC et al. | Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice. | 2013 | Int. J. Oncol. | pmid:23835587 |
Beguin Y et al. | Darbepoetin-alfa and intravenous iron administration after autologous hematopoietic stem cell transplantation: a prospective multicenter randomized trial. | 2013 | Am. J. Hematol. | pmid:23873823 |
Munoz C et al. | Klotho sensitivity of the hERG channel. | 2013 | FEBS Lett. | pmid:23603386 |
Lynn S and McDaniel J | Managing severe anemia when the patient is a Jehovah's Witness. | 2013 | JAAPA | pmid:23610833 |
Biggar P and Hahn KM | [Importance of the different i.v. iron generations for everyday medical practice]. | 2013 | MMW Fortschr Med | pmid:23678667 |
Beck-da-Silva L et al. | IRON-HF study: a randomized trial to assess the effects of iron in heart failure patients with anemia. | 2013 | Int. J. Cardiol. | pmid:23680589 |
Goldstein SL et al. | Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial. | 2013 | Am. J. Kidney Dis. | pmid:23245582 |
Blanco Rubio N et al. | [Preoperative intravenous iron as a strategy for blood saving in surgery for hip fracture]. | 2013 | Med Clin (Barc) | pmid:23246172 |
Lee ES et al. | Comparison of adverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. | 2013 | Curr Med Res Opin | pmid:23252876 |
Giger M and Achermann R | [Iron substitution in outpatients in Switzerland: Increase of costs associated with intravenous administration]. | 2013 | Z Evid Fortbild Qual Gesundhwes | pmid:23916272 |
Beck-da-Silva L et al. | Iron therapy in patients with heart failure. A straight shot. | 2013 | Int. J. Cardiol. | pmid:23931974 |
Vadasz D et al. | Intravenous iron sucrose for restless legs syndrome in pregnant women with low serum ferritin. | 2013 | Sleep Med. | pmid:24012019 |
Tian B et al. | Predicting enzyme-substrate specificity with QM/MM methods: a case study of the stereospecificity of (D)-glucarate dehydratase. | 2013 | Biochemistry | pmid:23901785 |
Abdel-Razeq H et al. | Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study. | 2013 | Drug Des Devel Ther | pmid:24039403 |
Kalaivani K | Use of intravenous iron sucrose for treatment of anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056552 |
Kriplani A et al. | Intravenous iron sucrose therapy for moderate to severe anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056559 |
Michigami T | [Updates on rickets and osteomalacia: FGF23-mediated hypophosphatemic rickets/osteomalacia]. | 2013 | Clin Calcium | pmid:24076640 |
Italia K et al. | Hydroxyurea could be a good clinically relevant iron chelator. | 2013 | PLoS ONE | pmid:24349400 |
Grim K et al. | Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. | 2013 | Sleep Med. | pmid:23993871 |
Athibovonsuk P et al. | Prevention of blood transfusion with intravenous iron in gynecologic cancer patients receiving platinum-based chemotherapy. | 2013 | Gynecol. Oncol. | pmid:24099839 |