| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tokola O et al. | Hepatic drug-oxidizing enzyme systems and urinary D-glucaric acid excretion in patients with congestive heart failure. | 1975 | Br J Clin Pharmacol | pmid:786355 |
| Street JC and Chadwick RW | Ascorbic acid requirements and metabolism in relation to organochlorine pesticides. | 1975 | Ann. N. Y. Acad. Sci. | pmid:54013 |
| Spencer-Peet J et al. | Urinary d-glucaric acid excretion and serum gamma-glutamyl transpeptidase activity in alcoholism. | 1975 | Br J Addict Alcohol Other Drugs | pmid:2272 |
| Malaka-Zafiriu K et al. | D-Glucaric acid excretion in newborns with severe jaundice of unknown etiology and due to glucose-6-phosphate dehydrogenase deficiency in Greece. | 1975 | Helv Paediatr Acta | pmid:807541 |
| Marselos M et al. | Aldehyde dehydrogenase inducibility and ethanol preference in rats. | 1975 | Med. Biol. | pmid:810629 |
| Marselos M and Laitinen M | Starvation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa. | 1975 | Biochem. Pharmacol. | pmid:811226 |
| Latham AN | Effect of in vitro changes in urinary pH on the enzymatic measurement and daily variation in excretion of D-glucaric acid. | 1975 | J. Pharm. Pharmacol. | pmid:239180 |
| Roots I et al. | Comparison of methods to study enzyme induction in man. | 1975 | Adv. Exp. Med. Biol. | pmid:239546 |
| Smirne S et al. | [Serum gamma-glutamyl-transpeptidase and urinary excretion of D-glucaric acid in epileptic patients treated with anticonvulsants]. | 1974 Jul-Aug | Riv Neurol | pmid:4155805 |
| Simmons CJ et al. | Urinary D-glucaric acid assay by an improved enzymatic procedure. | 1974 | Clin. Chim. Acta | pmid:4856673 |
| Cassimos C et al. | Urinary D-glucaric acid excretion in normal and G-6-PD-deficient children with favism. | 1974 | J. Pediatr. | pmid:4826626 |
| Furuno K et al. | Effect of D-glucaric acid derivatives on stability of rat liver lysosomes and erythrocytes. | 1974 | Jpn. J. Pharmacol. | pmid:4463271 |
| Hinohara Y et al. | Glucuronic acid pathway in alloxan diabetic rabbits. (I). Urinary excretion of metabolites related to the glucuronic acid pathway. | 1974 | Jpn. J. Pharmacol. | pmid:4463273 |
| March J et al. | Values for urinary excretion of D-glucaric acid by normal individuals. | 1974 | Clin. Chem. | pmid:4416840 |
| Cunningham JL and Evans DA | Urinary D-glucaric acid excretion and acetanilide pharmacokinetics before and during diphenylhydantoin administration. | 1974 | Eur. J. Clin. Pharmacol. | pmid:4417891 |
| Hunter J et al. | Changes in D-glucaric acid excretion in relationship to alterations in the rate of antipyrine metabolism in man. | 1974 | Biochem. Pharmacol. | pmid:4429583 |
| Del Ninno E et al. | [The d-glucaric acid test in the evaluation of the inductive properties of phenobarbital and spironalactone]. | 1974 | Acta Vitaminol. Enzymol. | pmid:4480343 |
| Sotaniemi EA et al. | Glucaric acid as an indicator of use of enzyme-inducing drugs. | 1974 | Clin. Pharmacol. Ther. | pmid:4150733 |
| Latham AN | D-Glucaric acid as an index of hepatic enzyme induction by anticonvulsant drugs in man. | 1974 | J. Pharm. Pharmacol. | pmid:4151390 |
| Smith SE and Rawlins MD | Prediction of drug oxidation rates in man: lack of correlation with serum gamma-glutamyl transpeptidase and urinary excretion of D-glucaric acid and 6 beta-hydroxycortisol. | 1974 | Eur. J. Clin. Pharmacol. | pmid:4153008 |
| Davidson DC et al. | Assessment of plasma glutamyl transpeptidase activity and urinary D-glucaric acid excretion as indices of enzyme induction. | 1974 | Clin Sci Mol Med | pmid:4154014 |
| Edwards OM et al. | Changes in cortisol metabolism following rifampicin therapy. | 1974 | Lancet | pmid:4140269 |
| Sartor P and Cohere G | [Iron saccharate capture by rat uterus epithelium. Experimental study with respect to hormonal status]. | 1973 | C. R. Seances Soc. Biol. Fil. | pmid:4794498 |
| Notten WR and Henderson PT | Effect of disulfiram on the urinary D-glucaric acid excretion and activity of some enzymes involved in drug metabolism in guinea-pig. | 1973 | Arch Int Pharmacodyn Ther | pmid:4357069 |
| Young RS | Determination of calcium oxide in calcined phosphate ores. | 1973 | Talanta | pmid:18961359 |
| Hunter J et al. | Urinary D-glucaric acid excretion and total liver content of cytochrome P-450 in guinea-pigs: relationship during enzyme induction and following inhibition of protein synthesis. | 1973 | Biochem. Pharmacol. | pmid:4693495 |
| Matsui M et al. | Studies on the glucaric acid pathway in the metabolism of D-glucuronic acid in mammals. IV. Fluorometric method for the determination of D-glucaric acid in serum. | 1972 | Chem. Pharm. Bull. | pmid:5065229 |
| Maxwell JD et al. | Folate deficiency after anticonvulsant drugs: an effect of hepatic enzyme induction? | 1972 | Br Med J | pmid:5008482 |
| Masaki H | [Metabolic pathway of D-glucaric acid synthesis from D-glucuronolactone in the skin. II. Identification of the intermediates in D-glucuronolactone D-glucaric acid metabolism]. | 1972 | Nihon Hifuka Gakkai Zasshi | pmid:4540858 |
| Nasaki H | [Metabolic pathway of D-glucaric acid synthesis from D-glucuronolactone in the skin. 1. D-glucaric acid and D-glucuronolactone dehydrogenase activities in the human skin--feedback mechanism of beta-glucuronidase]. | 1972 | Nihon Hifuka Gakkai Zasshi | pmid:4540880 |
| Hunter J et al. | Altered calcium metabolism in epileptic children on anticonvulsants. | 1971 | Br Med J | pmid:5115570 |
| Hunter J et al. | Urinary d-glucaric acid excretion as a measure of hepatic enzyme induction in man. | 1971 | Clin Sci | pmid:5550888 |
| Hunter J et al. | Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man. | 1971 | Lancet | pmid:4100904 |
| Aarts EM | D-glucaric-acid excretion as a test for hepatic enzyme induction. | 1971 | Lancet | pmid:4102545 |
| Hunter J et al. | D-glucaric-acid excretion as a test for hepatic enzyme induction. | 1971 | Lancet | pmid:4103690 |
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| RICHTER GW | Intranuclear aggregates of ferritin in liver cells of mice treated with saccharated iron oxide. Their possible relation to nuclear protein synthesis. | 1961 | J Biophys Biochem Cytol | pmid:13741388 |
| RICHTER GW | The cellular transformation of injected colloidal iron complexes into ferritin and hemosiderin in experimental animals; a study with the aid of electron microscopy. | 1959 | J. Exp. Med. | pmid:13620849 |
| BOYLAND E et al. | Enzyme activity in relation to cancer: inhibition of urinary beta-glucuronidase of patients with cancer of the bladder by oral administration of 1:4-saccharolactone and related compounds. | 1957 | Br. J. Cancer | pmid:13510516 |
| ELLIS JT | Glomerular lesions and the nephrotic syndrome in rabbits given saccharated iron oxide intravenously; with special reference to the part played by intracapillary precipitates in the pathogenesis of the lesions. | 1956 | J. Exp. Med. | pmid:13278460 |
| DEVOE RW and MOSES LE | Iron therapy in pregnancy; a comparative study of various modes. | 1954 | Calif Med | pmid:13209356 |
| NISSIM JA | Toxic reactions after intravenous saccharated iron oxide in man; suggestions for improved preparations. | 1954 | Br Med J | pmid:13115719 |
| WHITE LP et al. | The immediate hematologic effects of intravenous saccharated iron oxide. | 1952 | Blood | pmid:14953947 |
| DESHMUKH PL | Intravenous iron therapy with saccharated iron oxide. | 1952 | Ind Med Gaz | pmid:12990194 |
| LEVVY GA | The inhibition of beta-glucuronidase by derivatives of saccharic acid. | 1952 | Biochem. J. | pmid:14915974 |
| HOLLY RG | Intravenous iron: evaluation of the use of saccharated iron oxide in iron deficiency states in obstetrics and gynecology. | 1951 | Blood | pmid:14869375 |
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