Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypercalcemia D006934 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lung Neoplasms D008175 171 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Carbon Tetrachloride Poisoning D002252 12 associated lipids
Femoral Neck Fractures D005265 3 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Galutira PJ and Del Rio M Understanding renal posttransplantation anemia in the pediatric population. 2012 Pediatr. Nephrol. pmid:22086345
Aspuru K et al. Optimal management of iron deficiency anemia due to poor dietary intake. 2011 Int J Gen Med pmid:22114518
Kim Y et al. Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. 2011 Nutr Res pmid:22118754
Menendez C et al. Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed? 2011 Mol Nutr Food Res pmid:22144045
Toblli JE et al. Evaluation of toxicity and oxidative stress induced by intravenous iron isomaltoside 1000 in a nonclinical model. 2011 Arzneimittelforschung pmid:22164963
Wada Y et al. [Case report; A case of FGF23-related hypophosphatemic osteomalacia caused by long-term administration of saccharated ferric oxide]. 2011 Nippon Naika Gakkai Zasshi pmid:22175146
Stein J et al. Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. 2012 Curr Med Res Opin pmid:22181342
Ernst MC et al. Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. 2012 Endocrinology pmid:22186410
Cheng D et al. A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. 2011 Curr Radiopharm pmid:22191610
Kamanna VS et al. Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. 2012 Am. J. Nephrol. pmid:22212390
Rashid K et al. Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. 2012 Free Radic. Res. pmid:22239106
Smith TN et al. Modifications in the nitric acid oxidation of D-glucose. 2012 Carbohydr. Res. pmid:22285512
Stachowska-Pietka J et al. Computer simulations of osmotic ultrafiltration and small-solute transport in peritoneal dialysis: a spatially distributed approach. 2012 Am. J. Physiol. Renal Physiol. pmid:22301624
Kumbasar A et al. The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. 2012 Sep-Oct J. Nephrol. pmid:22307439
Toblli JE et al. Comparison of oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model. 2012 Inflamm Allergy Drug Targets pmid:22309085
Muñoz M et al. Effects of postoperative intravenous iron on transfusion requirements after lower limb arthroplasty. 2012 Br J Anaesth pmid:22337966
Nasir A et al. Management of iron deficiency anaemia in gynaecological patients at Jinnah Postgraduate Medical Centre, Karachi. 2011 J Pak Med Assoc pmid:22356035
pmid:22364593
Galindo P et al. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. 2012 PLoS ONE pmid:22427863
Bidossi A et al. A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. 2012 PLoS ONE pmid:22428019
pmid:22530898
Wyffels L et al. Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate. 2012 Mol Imaging pmid:22554483
Sricholpech M et al. Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. 2012 J. Biol. Chem. pmid:22573318
Ceretta LB et al. Increased oxidative stress and imbalance in antioxidant enzymes in the brains of alloxan-induced diabetic rats. 2012 Exp Diabetes Res pmid:22645603
Nambara K [Clinical and experimental studies on the enzymes of liver, small intestinal mucosa and pancreas after chronic ethanol ingestion and anti-epileptic drugs (author's transl)]. 1979 Hokkaido Igaku Zasshi pmid:226466
De Sousa A and Kalra G Drug therapy of attention deficit hyperactivity disorder: current trends. 2012 Mens Sana Monogr pmid:22654382
Smith AA et al. The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. 2012 PLoS Comput. Biol. pmid:22693442
Conner TA et al. Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. 2012 Biometals pmid:22706571
Spencer-Peet J et al. Urinary d-glucaric acid excretion and serum gamma-glutamyl transpeptidase activity in alcoholism. 1975 Br J Addict Alcohol Other Drugs pmid:2272
Ichii H et al. Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. 2012 Am. J. Nephrol. pmid:22722756
Pfenniger A et al. Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. 2012 J Perinat Med pmid:22752771
da Silva Krause M et al. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. 2012 J. Endocrinol. pmid:22761278
pmid:22771376
pmid:22820017
Walters KR et al. Methamphetamine causes anorexia in Drosophila melanogaster, exhausting metabolic reserves and contributing to mortality. 2012 J Toxicol Sci pmid:22863857
Reinisch W et al. State of the iron: how to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease. 2013 J Crohns Colitis pmid:22917870
Adhikary L and Acharya S Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. 2011 Jul-Sep JNMA J Nepal Med Assoc pmid:22922860
Kochhar PK et al. Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial. 2013 J. Obstet. Gynaecol. Res. pmid:22925176
Freburger JK et al. Changing patterns of anemia management in US hemodialysis patients. 2012 Am. J. Med. pmid:22938926
pmid:22940889
Christoph P et al. Intravenous iron treatment in pregnancy: comparison of high-dose ferric carboxymaltose vs. iron sucrose. 2012 J Perinat Med pmid:22945271
Borchard G et al. Nanoparticle iron medicinal products - Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies. 2012 Regul. Toxicol. Pharmacol. pmid:22951348
pmid:22954919
Okam MM et al. Comparative rates of adverse events with different formulations of intravenous iron. 2012 Am. J. Hematol. pmid:22965928
Yamamoto S et al. Fibroblast growth factor 23-related osteomalacia caused by the prolonged administration of saccharated ferric oxide. 2012 Intern. Med. pmid:22975552
Pasquini R et al. Urine mutagenicity and biochemical parameters as markers of exposure to petroleum pitch using a rat model. 1990 Environ. Mol. Mutagen. pmid:2298199
Wilson PD et al. An analysis of the health service efficiency and patient experience with two different intravenous iron preparations in a UK anaemia clinic. 2013 J Med Econ pmid:22989163
Rostoker G et al. Hemodialysis-associated hemosiderosis in the era of erythropoiesis-stimulating agents: a MRI study. 2012 Am. J. Med. pmid:22998881
Walaszek Z et al. Antiproliferative effect of dietary glucarate on the Sprague-Dawley rat mammary gland. 1990 Cancer Lett. pmid:2302696
Xia B et al. A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. 2012 Mol. Pharm. pmid:23033922