| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mycobacterium Infections | D009164 | 7 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Carbon Tetrachloride Poisoning | D002252 | 12 associated lipids |
| Femoral Neck Fractures | D005265 | 3 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hanaue H et al. | Estimation of the functional reserve of the human liver by urinary D-glucaric acid excretion after vitamin C administration. | 1993 | Tokai J. Exp. Clin. Med. | pmid:7940601 |
| Sacco C et al. | Selective inhibition of gastrointestinal beta-glucuronidase by polyvinylbenzyl D-glucaro(1,4)lactonate: attachment of D-glucaro(1,4)lactone to polyvinylbenzyl chloride. | 1993 | Hum Exp Toxicol | pmid:8096720 |
| Okuyama T et al. | [Measurement and its fluctuation of urinary glucaric acid in newborns]. | 1993 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:8340644 |
| Abou-Issa H et al. | Basis for the anti-tumor and chemopreventive activities of glucarate and the glucarate:retinoid combination. | 1993 Mar-Apr | Anticancer Res. | pmid:8517653 |
| Poon R et al. | HPLC determination of D-glucaric acid in human urine. | 1993 May-Jun | J Anal Toxicol | pmid:8336488 |
| Webb TE et al. | Mechanism of growth inhibition of mammary carcinomas by glucarate and the glucarate: retinoid combination. | 1993 Nov-Dec | Anticancer Res. | pmid:8297119 |
| Konjiki O et al. | [A case of hypophosphatemia induced by intravenous administration of saccharated iron oxide]. | 1994 | Nihon Ronen Igakkai Zasshi | pmid:7853746 |
| Sacco C and Calabrese EJ | Selective inhibition of gastrointestinal beta-glucuronidase by poly(vinylbenzyl D-glucaro(1,4)lactonate). Part 2. Poly(vinylbenzyl D-glucaro(1,4) lactonate) in vitro inhibition studies. | 1994 | Hum Exp Toxicol | pmid:7857695 |
| Nakamura T et al. | A novel oligosaccharide, GlcA beta 1-4Xyl beta 1-(4-methylumbelliferone), synthesized by human cultured skin fibroblasts. | 1994 | Biochem. J. | pmid:7818474 |
| Fuchs W et al. | Lansoprazole does not affect the bioavailability of oral contraceptives. | 1994 | Br J Clin Pharmacol | pmid:7833230 |
| Ciuffi M et al. | Effect of 21-aminosteroid U74500A (pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(5,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl-, HCl (16 alpha)) on rat brain cortex lipid peroxidation induced "in vivo" by iron-carbohydrate. | 1994 | Biochem. Pharmacol. | pmid:8031311 |
| Previs SF et al. | Use of [6,6-2H2]glucose and of low-enrichment [U-13C6]-glucose for sequential or simultaneous measurements of glucose turnover by gas chromatography-mass spectrometry. | 1994 | Anal. Biochem. | pmid:8053553 |
| Fujimoto T et al. | A new clinical prognostic predictor for patients with biliary atresia. | 1994 | J. Pediatr. Surg. | pmid:8078014 |
| Ferreira M et al. | Determinants of urinary thioethers, D-glucaric acid and mutagenicity after exposure to polycyclic aromatic hydrocarbons assessed by air monitoring and measurement of 1-hydroxypyrene in urine: a cross-sectional study in workers of coke and graphite-electrode-producing plants. | 1994 | Int Arch Occup Environ Health | pmid:8175189 |
| Newman MA et al. | Urinary biological monitoring markers of anticancer drug exposure in oncology nurses. | 1994 | Am J Public Health | pmid:8179062 |
| Wiśniewska-Knypl JM and Wrońska-Nofer T | Biological markers of oxidative stress induced by ethanol and iron overload in rat. | 1994 | Int J Occup Med Environ Health | pmid:7719662 |
| Ageeva TA and ShkurupiÄ VA | [Protective effect of the lysosomotrophic preparation rheopolyglucin in treating iron-deficient anemia with iron saccharate]. | 1994 | Biull Eksp Biol Med | pmid:7522618 |
| Webb TE et al. | Pharmacokinetics relevant to the anti-carcinogenic and anti-tumor activities of glucarate and the synergistic combination of glucarate:retinoid in the rat. | 1994 | Biochem. Pharmacol. | pmid:8185680 |
| Curley RW et al. | Activity of D-glucarate analogues: synergistic antiproliferative effects with retinoid in cultured human mammary tumor cells appear to specifically require the D-glucarate structure. | 1994 | Life Sci. | pmid:8190001 |
| Mizumoto Y et al. | [Measurement and fluctuation of urinary glucaric acid in pregnant women]. | 1994 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:8089594 |
| Franco G and Fonte R | Advances in evaluating liver response to operating theatre work: urinary D-glucaric acid as an index of effect. | 1994 | Occup Med (Lond) | pmid:8167312 |
| Edwards JW and Priestly BG | Effect of occupational exposure to aldrin on urinary D-glucaric acid, plasma dieldrin, and lymphocyte sister chromatid exchange. | 1994 | Int Arch Occup Environ Health | pmid:7843832 |
| Tsuruoka T et al. | Inhibition of pulmonary metastases and tumor cell invasion in experimental tumors by sodium D-glucaro-delta-lactam (ND2001). | 1995 | Jpn. J. Cancer Res. | pmid:7737908 |
| Tsuruoka T et al. | Inhibition of tumor cell haptotaxis by sodium D-glucaro-delta-lactam (ND2001). | 1995 | Jpn. J. Cancer Res. | pmid:8567400 |
| Reidenberg P et al. | Effects of felbamate on the pharmacokinetics of phenobarbital. | 1995 | Clin. Pharmacol. Ther. | pmid:7554701 |
| Heerdt AS et al. | Calcium glucarate as a chemopreventive agent in breast cancer. | 1995 Feb-Mar | Isr. J. Med. Sci. | pmid:7744577 |
| Bisio S and Franco G | Drinking habits and occupational exposure to xenobiotics: a review. | 1995 Jan-Nov | G Ital Med Lav | pmid:8940655 |
| Abou-Issa H et al. | Relative efficacy of glucarate on the initiation and promotion phases of rat mammary carcinogenesis. | 1995 May-Jun | Anticancer Res. | pmid:7645962 |
| Addyman R et al. | Urinary glucaric acid excretion in rheumatoid arthritis: influence of disease activity and disease modifying drugs. | 1996 | Ann. Rheum. Dis. | pmid:8774168 |
| Moretti M et al. | Biological monitoring of genotoxic hazard in workers of the rubber industry. | 1996 | Environ. Health Perspect. | pmid:8781380 |
| Sung RY et al. | Urinary D-glucaric acid excretion in idiopathic neonatal jaundice. | 1996 | Chin. Med. J. | pmid:8758309 |
| Monarca S et al. | Biological monitoring of workers exposed to N-nitrosodiethanolamine in the metal industry. | 1996 | Environ. Health Perspect. | pmid:8834865 |
| Meyer MP et al. | A comparison of oral and intravenous iron supplementation in preterm infants receiving recombinant erythropoietin. | 1996 | J. Pediatr. | pmid:8765624 |
| Meier JR et al. | Urine mutagenicity and biochemical effects of the drinking water mutagen, 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX), following repeated oral administration to mice and rats. | 1996 | Toxicology | pmid:8658560 |
| Silverberg DS et al. | Intravenous iron supplementation for the treatment of the anemia of moderate to severe chronic renal failure patients not receiving dialysis. | 1996 | Am. J. Kidney Dis. | pmid:8659499 |
| Mercuriali F | Epoetin alfa increases the volume of autologous blood donated by patients scheduled to undergo orthopedic surgery. | 1996 | Semin. Hematol. | pmid:8723574 |
| Mercuriali F | Epoetin alfa for autologous blood donation in patients with rheumatoid arthritis and concomitant anemia. | 1996 | Semin. Hematol. | pmid:8723576 |
| Tryba M | Epoetin alfa plus autologous blood donation in patients with a low hematocrit scheduled to undergo orthopedic surgery. | 1996 | Semin. Hematol. | pmid:8723577 |
| Collinot JP et al. | Evaluation of urinary D-glucaric acid excretion in workers exposed to butyl glycol. | 1996 | J Toxicol Environ Health | pmid:8691506 |
| Sunder-Plassmann G and Hörl WH | Safety of intravenous injection of iron saccharate in haemodialysis patients. | 1996 | Nephrol. Dial. Transplant. | pmid:8918625 |
| Lorincz M et al. | Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase. | 1996 | Cytometry | pmid:8866216 |
| Brunelle FM and Verbeeck RK | Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. | 1996 | Xenobiotica | pmid:8867997 |
| Silverberg DS et al. | Intravenous ferric saccharate as an iron supplement in dialysis patients. | 1996 | Nephron | pmid:8852489 |
| Sunder-Plassmann G and Hörl WH | Safety aspects of parenteral iron in patients with end-stage renal disease. | 1997 | Drug Saf | pmid:9352960 |
| Cynke E | [Parenteral iron replacement]. | 1997 | Praxis (Bern 1994) | pmid:9312810 |
| al-Hawas F et al. | Use of i.v. iron saccharate in haemodialysis patients not responding to oral iron and erythropoietin. | 1997 | Nephrol. Dial. Transplant. | pmid:9430909 |
| Sandle LN et al. | Indirect evidence for hepatic induction in patients with cholesterol gallstones. | 1997 | Biochem. Soc. Trans. | pmid:9388642 |
| Miguel JC et al. | Effects of iron salts in sucrose on dental caries and plaque in rats. | 1997 | Arch. Oral Biol. | pmid:9233847 |
| Brunelle FM and Verbeeck RK | Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat. | 1997 | Life Sci. | pmid:9180355 |
| Scassellati-Sforzolini G et al. | In vivo studies on genotoxicity of pure and commercial linuron. | 1997 | Mutat. Res. | pmid:9186570 |