Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypercalcemia D006934 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lung Neoplasms D008175 171 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Carbon Tetrachloride Poisoning D002252 12 associated lipids
Femoral Neck Fractures D005265 3 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Bologa M et al. Pregnancy-induced changes in drug metabolism in epileptic women. 1991 J. Pharmacol. Exp. Ther. pmid:2033516
PERSOONIAL Reflections. 2009 Persoonia pmid:20198167
pmid:20162193
Gredilla E et al. [Treating severe acute anemia due to vaginal bleeding in the Jehovah's Witness: a report of 2 cases]. 2009 Rev Esp Anestesiol Reanim pmid:20151526
Li LO et al. Early hepatic insulin resistance in mice: a metabolomics analysis. 2010 Mol. Endocrinol. pmid:20150186
Moon TS et al. Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli. 2010 Metab. Eng. pmid:20117231
Kowalczyk MC et al. Synergistic effects of combined phytochemicals and skin cancer prevention in SENCAR mice. 2010 Cancer Prev Res (Phila) pmid:20103723
Chaudhuri RR et al. Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. 2010 PLoS ONE pmid:20098708
Ranganathan P and Pramesh CS Letter 1: Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery (Br J Surg 2009; 96: 1122-1128). 2010 Br J Surg pmid:20069595
Simpson JA et al. Letter 2: Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery (Br J Surg 2009; 96: 1122-1128). 2010 Br J Surg pmid:20069594
Hu Q et al. Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. 2010 Lab. Invest. pmid:20065947
Dangsuwan P and Manchana T Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy. 2010 Gynecol. Oncol. pmid:20051288
Ginsberg G and Rice DC Does rapid metabolism ensure negligible risk from bisphenol A? 2009 Environ. Health Perspect. pmid:20049111
Fior S and Gerola PD Impact of ubiquitous inhibitors on the GUS gene reporter system: evidence from the model plants Arabidopsis, tobacco and rice and correction methods for quantitative assays of transgenic and endogenous GUS. 2009 Plant Methods pmid:20042078
Sienkiewicz-Porzucek A et al. Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth. 2010 Mol Plant pmid:20035036
Stancu S et al. Can the response to iron therapy be predicted in anemic nondialysis patients with chronic kidney disease? 2010 Clin J Am Soc Nephrol pmid:20019121
Gambini JP et al. Evaluation of patients with head and neck cancer by means of 99mTc-glucarate. 2009 J Nucl Med Technol pmid:19949020
Morimoto S et al. Significance of urinary glucaric acid measurement and its application to paclitaxel therapy. 2009 Gan To Kagaku Ryoho pmid:19920388
Orlandi C et al. Early scintigraphic detection of experimental myocardial infarction in dogs with technetium-99m-glucaric acid. 1991 J. Nucl. Med. pmid:1992031
McMahon LP et al. Maintenance of elevated versus physiological iron indices in non-anaemic patients with chronic kidney disease: a randomized controlled trial. 2010 Nephrol. Dial. Transplant. pmid:19906658
Ball LM et al. Formation of mutagenic urinary metabolites from 1-nitropyrene in germ-free and conventional rats: role of the gut flora. 1991 Carcinogenesis pmid:1988167
Comín-Colet J et al. A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: influence on neurohormonal activation and clinical outcomes. 2009 J. Card. Fail. pmid:19879457
Smith TG et al. Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials. 2009 JAMA pmid:19809026
Muñoz M et al. Intravenous iron in inflammatory bowel disease. 2009 World J. Gastroenterol. pmid:19787830
Gehret TC et al. Convenient large-scale synthesis of D-glucaro-1,4:6,3-dilactone. 2009 J. Org. Chem. pmid:19777999
Edwards TJ et al. Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery. 2009 Br J Surg pmid:19731228
pmid:19717754
DeLisa MP and Conrado RJ Synthetic metabolic pipelines. 2009 Nat. Biotechnol. pmid:19668178
Dong T and Schellhorn HE Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933. 2009 BMC Genomics pmid:19650909
Dueber JE et al. Synthetic protein scaffolds provide modular control over metabolic flux. 2009 Nat. Biotechnol. pmid:19648908
Barraclough KA et al. Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial). 2009 BMC Nephrol pmid:19635169
Yi CX et al. A major role for perifornical orexin neurons in the control of glucose metabolism in rats. 2009 Diabetes pmid:19592616
Li H and Wang SX [Intravenous iron sucrose in maintenance dialysis patients with renal anemia: a clinical study]. 2009 Zhonghua Yi Xue Za Zhi pmid:19567093
Shimizu Y et al. Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. 2009 Bone pmid:19555782
Toblli JE et al. Differences between original intravenous iron sucrose and iron sucrose similar preparations. 2009 Arzneimittelforschung pmid:19517894
Krafft A et al. Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone. 2009 Fetal. Diagn. Ther. pmid:19506383
Fontés G et al. Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. 2009 Diabetes pmid:19502418
Nguyen TV Comparison of serum ferritin and transferrin saturation values associated with two i.v. iron formulations in hemodialysis patients. 2009 Am J Health Syst Pharm pmid:19498125
García-Erce JA et al. Efficacy of preoperative recombinant human erythropoietin administration for reducing transfusion requirements in patients undergoing surgery for hip fracture repair. An observational cohort study. 2009 Vox Sang. pmid:19497085
Asma S et al. Safety, therapeutic effectiveness, and cost of parenteral iron therapy. 2009 Int. J. Hematol. pmid:19495930
Kulnigg S et al. Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment. 2009 Am. J. Gastroenterol. pmid:19491860
Grote L et al. A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome. 2009 Mov. Disord. pmid:19489063
pmid:19481054
Luo Z et al. Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells. 2009 Endocrine pmid:19440859
pmid:19432851
Bencaiova G et al. Iron prophylaxis in pregnancy: intravenous route versus oral route. 2009 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:19406557
pmid:19379368
De Saint-Hubert M et al. Molecular imaging of cell death. 2009 Methods pmid:19362149
Nakamura Y et al. Decreased valproate level caused by VPA-glucuronidase inhibition by carbapenem antibiotics. 2008 Drug Metab Lett pmid:19356106
Gorder V et al. Treatment of restless legs syndrome with iron infusion therapy. 2009 JAAPA pmid:19354112